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| Author(s): |
Romualdo Maffra Júnior
Total Authors: 1
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| Document type: | Doctoral Thesis |
| Press: | São Paulo. |
| Institution: | Universidade de São Paulo (USP). Faculdade de Medicina (FM/SBD) |
| Defense date: | 2003-12-17 |
| Examining board members: |
Jose Guilherme Mendes Pereira Caldas;
Nitamar Abdala;
Francisco Cesar Carnevale;
Claudio Campi de Castro;
Ilka Regina Souza de Oliveira
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| Advisor: | Jose Guilherme Mendes Pereira Caldas |
| Abstract | |
Twelve mongrel dogs were used in this study to create abdominal aortic aneurysm (AAA) with endoleak after endovascular treatment. The next step was seal this endoleak with an embolic material called Onyx(R) The presence or occlusion of the endoleaks was proved by computer tomography and angiography. Succeed in the creation of the experimental model was observed in 9/12 dogs. OnyxÒ was capable to seal endoleaks in all nine dogs that survived from AAA creation. The occlusion was stable until the end of the study and the histological analysis showed minimal inflammatory response to Onyx(R). (AU) | |