Infrastructure support for Embrapa Instrumentation’s laboratories
Infrastructure support for the laboratories of EMBRAPA Instrumentation
Mathematical modeling of the biological effects of ionizing radiation in cancer ce...
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Author(s): |
Erika Cavalcante Silva
Total Authors: 1
|
Document type: | Doctoral Thesis |
Press: | São Paulo. |
Institution: | Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB/SDI) |
Defense date: | 2011-08-26 |
Examining board members: |
Joao Dias de Toledo Arruda Neto;
José Gregorio Cabrera Gomez;
Alessandro Minillo;
Irma Nelly Gutierrez Rivera;
Odete Rocha
|
Advisor: | Joao Dias de Toledo Arruda Neto; Maria do Carmo Bittencourt de Oliveira |
Abstract | |
Microcystis are cyanobacteria exhibiting blooms formation and production of microcystin, a hepathotoxin responsible for poisoning and consequent development of hepathic tumors. The goals of this work are the study of the combined effect between gamma radiation with other exogenous physical agents in cells of Microcystis panniformis, as well to investigate the attenuation of microcystin by neutron and electron beams and gamma radiation. It was found out that combined treatments, as radiation with another physical agent, caused lowering of the cellular viability and that had attenuation of microcystin after your exposition at three kind of ionizing radiation. The results showed that with the association of physical agents it is possible to reduce the doses needed for the population control of Microcystis panniformis and that exposition of electron beams have proved to be the most indicated radiation type for attenuation of microcystin. (AU) |