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| Author(s): |
Carolina de Castro Castrighini
Total Authors: 1
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| Document type: | Master's Dissertation |
| Press: | Ribeirão Preto. |
| Institution: | Universidade de São Paulo (USP). Escola de Enfermagem de Ribeirão Preto (PCARP/BC) |
| Defense date: | 2014-01-28 |
| Examining board members: |
Elucir Gir;
Lis Aparecida de Souza Neves;
Renata Karina Reis
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| Advisor: | Elucir Gir |
| Abstract | |
Introduction: HIV infection associated with tuberculosis affects the dynamics of both pathologies. Objective: To assess the prevalence and factors associated with HIV/tuberculosis co-infection in individuals with tuberculosis between 2003 and 2011, registered in the municipality of Ribeirão Preto - SP. Methodology: This is a descriptive, cross-sectional, retrospective study; the subjects were all individuals with HIV/tuberculosis co-infection, residents of the municipality of Ribeirão Preto, who had been diagnosed, notified and registered in the TBweb program, the tuberculosis information system of the state of São Paulo. Data were initially obtained from TBweb. After the selection, the database was created using the linkage technique between the TBweb, SINAN, SISCEL and SICLOM databases, which contain information on HIV/Aids. Data were analyzed by means of the Statistical Package for the Social Sciences (SPSS), version 17.0 for Windows, using descriptive statistics, chi-square test and Odds Ratio. Results: Out of the 1277 individuals with tuberculosis registered in the TBweb between 2003 and 2011, 338 presented HIV/tuberculosis co-infection, showing a prevalence of 26.5%. Regarding demographic characteristics, 244 (72.2%) were male and the predominant age range was between 35 and 44 years (45.0%). As for race/skin color, 151 (44.7%) were Caucasian. A total of 308 (91.1%) cases were new. Regarding the outcome of the case, most of the individuals (58.9%) with the HIV/tuberculosis co-infection were cured. Pulmonary tuberculosis was the most common clinical form of the disease, found in 201 (59.5%) cases, followed by extrapulmonary tuberculosis in 90 (26.6%) individuals. With regard to the identification of which disease was notified first, most cases, 246 (72.8%), had records of the HIV/aids case prior to the notification of tuberculosis. A total of 189 (55.9%) individuals had a CD4-Positive T-Lymphocyte count lower than 200 cells/mm³ of blood, 201 (59.5%) followed antiretroviral therapy and 102 (30.2%) had a viral load between 1,001 and 100,000 copies. Conclusion: The prevalence of co-infected individuals was 26.5%, which is above the national rate. Most individuals were male, in a productive age and had a low CD4-Positive T- Lymphocyte count, with a prior diagnosis of HIV/aids to that of tuberculosis, evidencing the need for more actions aimed at the prevention of both diseases (AU) | |
| FAPESP's process: | 12/06251-2 - Prevalence of HIV/tuberculosis coinfection in individuals with tuberculosis notified in the city of Ribeirão Preto-SP |
| Grantee: | Carolina de Castro Castrighini |
| Support Opportunities: | Scholarships in Brazil - Master |