CV Lattes
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Secretaria de Desenvolvimento Econômico (São Paulo - Estado). Faculdade de Medicina de São José do Rio Preto (FAMERP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Ciências Biológicas from Universidade Estadual Paulista Júlio de Mesquita Filho, UNESP, SJ Rio Preto (1990), master's at Ciências Biológicas from Universidade Estadual Paulista Júlio de Mesquita Filho, UNESP, SJ Rio Preto (1993) and doctorate at Ciências Biológicas from Universidade Estadual Paulista Júlio de Mesquita Filho, UNESP, SJ Rio Preto (1998). Has experience in Genetics, focusing on Human and Medical Genetics, acting on the following subjects: síndrome de down, câncer de cabeça e pescoço, polimorfismos, biologia molecular and neurofibromatose. (Source: Lattes Curriculum)
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Research projects are developed at the Faculty of Medicine of São José do Rio Preto (FAMERP) related to the lines of research that are part of the Postgraduate Programs of the Institution and that belong to different areas. Our research infrastructure is largely based in Block U-6, built with financial assistance obtained from FINEP (Financier of Studies and Projects). In an area of 2,310…
The intrinsically deficient immune system in Down syndrome (DS) may contribute to the increased susceptibility to infections related to the main causes of hospitalization and death of these individuals and also seems to favor neurodegenerative processes like Alzheimer's Disease. Chromosome 21 trisomy can cause global changes in gene expression, including those not located on chromosome 21…
The phenotype of Down syndrome (DS), more frequent human chromosomal disorder, is complex and variable among individuals, and may include multiple dysmorphic features, immunologic abnormalities, congenital heart defects, learning disabilities, neurological disorders, among others. Studies show that some genes involved in the immune system have altered expression in individuals with DS, ho…
(Only some records are available in English at this moment)
Trisomy 21 (T21), given the third copy of cromosome 21, is marked by an altered gene expression that leads to a chronic inflammatory state and higher predisposal to several diseases. A promising way to minimize the impacts caused by this imbalance is to modulate the expression of genes associated with such diseases. The aim of this project is to characterize the inflammatory response and …
The latest catalog of gene annotation and microRNAs (miRNAs), non-coding RNAs molecules involved in post-transcriptional gene regulation of chromosome 21, includes more than 223 coding genes and 30 miRNAs (HGNC, 2019). The contribution of these miRNAs to the Down syndrome (DS) phenotype is poorly investigated, but there is evidence some change in their expression could be related to manif…
The intrinsically deficient immune system in Down's Syndrome (SD) possibly contributes to the increased susceptibility of infections, which are related to the main causes of hospitalization and death of these individuals and also seems to be involved in neurodegenerative processes such as the early manifestation of Alzheimer's disease. Chromosome 21 trisomy can cause global changes in gen…
(Only some records are available in English at this moment)
| 18 / 10 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 16 / 8 | Completed scholarships in Brazil |
| 35 / 19 | All research grants and scholarships |
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