CV Lattes
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Universidade de São Paulo (USP). Instituto de Química (IQ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
He holds a degree in Pharmacy and Biochemistry from the University of São Paulo (1990), a Master's in Biological Sciences (Biochemistry) from the same university (1992), and a Ph.D. in Analytical Chemistry from Marquette University, USA (1996). He furthered his training with a post-doctorate at UW-Madison (1997) and visiting professorships at Université Joseph Fourier (2006) and ENS-Lyon (2024). At the University of São Paulo (USP), he rose to the position of Full Professor in the Biochemistry Department in 2012, serving as its Head from 2018 to 2022. His extensive academic management experience includes serving as Coordinator of Graduate Programs in Biochemistry (two terms) and the Professional Master's Program (one term), Chair of the Graduate Committee at the Institute of Chemistry (one term), and University Director of National and International Academic Cooperation. His scientific recognition is evidenced by his membership in the Brazilian Academy of Sciences and the São Paulo State Academy of Sciences, as well as in specialized national societies. On the global stage, he actively holds leadership positions as Vice-President of the International Union of Photobiology, President of the Latin American Branch of the American Society of Photobiology, and a board member of international scientific societies, in addition to being co-editor-in-chief of two Elsevier journals in the fields of photochemistry and photobiology. His research, focused on the fundamental mechanisms of light interaction with biological systems and innovation in photoprotection, has yielded hundreds of publications, dozens of international research projects, and several patentsincluding a new ingredient currently being tested by an international corporationalong with consulting work for the dermocosmetics industry. He is the recipient of numerous awards, including the Photocyte B Award (American Society of Photobiology, twice), the Humanitarian Award (International Union of Photobiology), and the Research Award (LatASP). He complements his work with a commitment to education in entrepreneurship, having developed and taught a specific module on the subject for undergraduate and graduate students. (Source: Lattes Curriculum)
| Articles published in Pesquisa FAPESP Magazine about the researcher: |
| Otro peligro del Sol |
| Further danger from the sun |
| More dangerous than the sun |
| Otro peligro del Sol |
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| News published in Agência FAPESP Newsletter about the researcher |
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| Articles published in other media outlets ( ): |
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Sunlight is vital for life, yet its involvement in metabolic processes comes at a cost. When biomolecules absorb solar radiation, they become electronically excited, increasing their propensity for electron and energy transfer. This can lead to: (i) the production of reactive species that may be either beneficial or harmful, depending on their nature, quantity, and location, and (ii) evol…
The project presented here for this FAPERGS/FAPESP call is directly connected to the research lines that have been developed in the Bioinorganic and Porphyrinic Materials Laboratory (LBMP) at UFSM and in the Photoinduced Processes and Interfaces Laboratory (LPFI) at IQ-USP in recent years and which seeks to combine advances in porphyrin chemistry, especially new compounds with biomimetic …
Both groups (UK, whose PI is prof Pourzand and BR, whose PI is prof Baptista) study damage and protection of sun-exposed skin cells, aiming to develop better concepts and strategies for sun protection. The UK group is actively working in the role of iron and of photoaging and photoprotection in sun-exposed skin cells and the Brazilian group is doing similar efforts, but working mainly in …
(Only some records are available in English at this moment)
Singlet oxygen 1Deltag (1O2) is the first excited state of molecular oxygen with 94.3 kJ/mol in excess to its ground triplet state, and with a chemical reactivity completely different from that of molecular oxygen, as it can attack chemical bonds by two electron oxidations. 1O2 plays important roles in materials science, physics, chemistry, biology and medicine, being primarily responsibl…
Using the resources of the Technical Reserve for Institutional Infrastructure according to the rules specified by FAPESP. (AU)
(Only some records are available in English at this moment)
Photodynamic Therapy (PDT) is a technique based on the interaction of light with a photosensitizer, generating reactive oxygen species to destroy rapidly proliferating tissues, such as tumors. Riboflavin, or vitamin B2, is an essential compound for the human body, serving as a precursor to coenzymes critical for cellular energy production. Due to its photochemical properties, riboflavin c…
Photobiomodulation has gained prominence in clinical and aesthetic applications as a promising alternative for treating ulcers, chronic pain, neural regeneration, and skin photorejuvenation. In vivo and in vitro studies show that light in the red wavelength range can significantly alter cellular functions, promoting effects such as proliferation, cytokine secretion, differentiation, and c…
Convênio cadastrado a partir de informação enviada em e-mail semanal com dados do XML CPD (Thais)
(Only some records are available in English at this moment)
The present project aims to elucidate the influence of visible radiation, specifically blue and red wavelengths, on the processes of damage/inhibition and activation of skin cells. The literature describes that exposure to red light is related to cell activation. On the other hand, blue light is generally associated with harm. Visible light is capable of reaching both the dermis and epide…
Solar energy encompasses photons with different wavelengths of the electromagnetic spectrum, which correspond to ultraviolet rays, totaling around 2% of solar radiation, visible and infrared light, which correspond to the remaining 98%. The wavelength spectrum of visible light is between 400 nanometers (nm) and 750 nm. Recent studies indicate that this light is capable of affecting melano…
(Only some records are available in English at this moment)
The skin is continuously exposed to solar radiation and is our largest organ, offering an effective barrier against water loss and protection against external agents, among many other functions. Different light wavelengths have different effects on the skin. Most importantly for this project, they can differentially affect oxidative phosphorylation and metabolic fluxes in keratinocyte mit…
Sterols, referred to as the third lipid class, bear the essential triterpenoid scaffold, that ensure fluidity and flexibility to cell membranes, and serve as signaling important molecules crucial in growth, development and differentiation of organisms. The 7-Dehydrocholesterol (7-DHC) is a biosynthetic precursor of cholesterol and vitamin D3, and ergosterol. Similar to the polyunsaturated…
The project submitted here entitled "Ruthenium(II) complexes containing quinone based ligands to improve membrane damage and cause PDT response" is part of the postdoctoral project (2019/03195-3) and is related to a collaboration Project between Professor Mauricio da Silva Baptista (Universidade de São Paulo - Brazil) and Professor Claudia Turro (The Ohio State University). The strategy i…
Radical-mediated oxidations are expected to play an important role on photosensitized oxidations occuring in photodynamic therapy and cutaneous photoaging. Given the role of lipid photo-oxidation in these photobiological processes, in this project we aim to study the formation of lipid peroxyl radicals in model membranes, by using of BODIPY-a-tocopherol off/on fluorescent probes. These pr…
| 6 / 6 | Ongoing grants |
| 22 / 14 | Completed research grants |
| 5 / 5 | Ongoing scholarships in Brazil |
| 76 / 39 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 3 / 3 | Completed scholarships abroad |
| 113 / 68 | All research grants and scholarships |
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