CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Faculdade de Engenharia Química (FEQ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Engenharia Química from Universidade Estadual de Campinas (1994) and ph.d. at Chemical Engineering from Universidade Estadual de Campinas (2006). Has experience in Chemical Engineering, focusing on Characteristic Operations of Biochemical Processes, acting on the following subjects: lipase, liposome, gas chromatography, monoacylglycerols and vinyl esters. (Source: Lattes Curriculum)
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This multidisciplinary research project aims to consolidate a microfluidic platform for the synthesis of nanomaterials and encapsulation of repositioned therapeutic compounds. These formulations will be evaluated in spheroids operating in perfusion mode, emphasizing the strategy of drug-sustained release and microfluidic systems for screening drugs for oncological treatment. As a proof of…
The concept of organ-on-a-chip refers to different types of in vitro modeling or reproduction of tissues and organs by combining cells and biocompatible material. This approach has become an attractive alternative for various studies, such as drug testing. The initial push was the worldwide effort to reduce the number of lab animals used in research, by the application of the 3R's - repla…
This research project involves the activities of the Laboratory of Nano&Biotechnology for Advanced Developments (LaNBDA), under the coordination of the researcher responsible for this project. The research uses emerging technologies such as microfluidics and 3D bioprinting to develop new products and processes. Microfluidics is the science and technology that involves the manipulation of …
This research project encompasses the activities of the Laboratory of Nano&Biotechnology for Advanced Developments (LaNBDA), under coordination of the responsible researcher of this project. The research activities are targeted to the microfluidics area, which is the science and technology that allow manipulation of microscale devices and handles small amounts of fluids that flow in artif…
This research project encompasses the activities of the Laboratory of Nano&Biotechnology for Advanced Developments (LaNBDA), under coordination of the responsible researcher of this project. The research activities are targeted to the microfluidics area, which is the science and technology that allow manipulation of microscale devices and handless small amounts of fluids that flow in arti…
(Only some records are available in English at this moment)
Oral Squamous Cell Carcinoma (OSCC) is a type of cancer affecting a substantial portion of the global population, leading to premature deaths and considerable suffering among those affected. Its treatment depends mainly on surgery, radiotherapy, and chemotherapy. Chemotherapy employs cytotoxic agents that adversely impact the body, often resulting in significant side effects for patients.…
Microgel-based bioinks offer a promising approach to improving the cellular microenvironment and emerge in the field of 3D bioprinting as a breakthrough technology in the context of regenerative medicine, offering potential breakthroughs in wound healing. Microgels can also be used to deliver drugs, improving drug release and solubility. Droplet microfluidics is a widely used method in mi…
Despite the large increase in diseases involving the central nervous system (CNS) in recent decades, drug availability is still low. The major limitation is the permeation of drugs through the blood-brain barrier (BBB) to reach the site of therapeutic action. A strategy to overcome the limitation of drug delivery through the BBB is the use of biomimetic vesicles, with potential for target…
(Only some records are available in English at this moment)
This research project aims to develop cell delivery systems based on biocompatible polymeric matrices by microfluidic technology and 3D bioprinting. A systematic study will evaluate the potential of gellan gum and fibrin to form hybrid hydrogels in order to act as macrophage encapsulation systems, attending their structural and biological needs. The development of hybrid hydrogels is a st…
Gene therapy is a promising technique based on genetic material delivery to cells or tissues, aiming from vaccination to treatment or slowdown in the progress of blood, immune and nervous system diseases and cancer. However, the technique success is related to gene material transportation and delivery to a specific target cell with low levels of pathogenic effects. This transfer can be pe…
This research project aims to develop multifunctional systems to release nanovectors for co-delivery of nucleic acids into cells. In this project, two important aspects will be explored for gene therapy improvement: (i) the development of nanovectors for co-delivery of plasmid DNA (pDNA) and small interfering (siRNA-silencer); and (ii) the synthesis of hybrid micro-carrier system composed…
(Only some records are available in English at this moment)
The aging of the world's population and the development of degenerative diseases such as Alzheimer's, whose cure is still unknown, have required the creation of new strategies that make it possible to study them more efficiently and quickly. However, developing new drugs to prevent and treat these diseases depends on drug delivery strategies that can cross the blood-brain barrier (BBB). T…
Gene therapy is a therapeutic strategy based on the intracellular delivery of genetic material (DNA or RNA). It is particularly promising to treat severe diseases for which the pathophysiology and genetic targets are known, e.g., cancer. In general, the success of gene therapy depends on (I) the protection of genetic material against nuclease-mediated degradation in the body fluids and (I…
Over the past decades, several comprehensive studies have led to the discovery of efficient treatment or prevention methods against genetic diseases. Among all methods, gene therapy, which is the introduction of suitable genetic material into specific cells to correct the abnormal genes, came out as a critical approach for this purpose. One of the crucial steps of gene therapy is understa…
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing grants |
| 9 / 9 | Completed research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 15 / 13 | Completed scholarships in Brazil |
| 9 / 9 | Completed scholarships abroad |
| 39 / 37 | All research grants and scholarships |
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