CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Bauru. Faculdade de Ciências (FC) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Licenciatura Plena em Educação Física from Universidade de São Paulo (1991) and ph.d. at Physiology from Universidade de São Paulo (1998). Has experience in Physiology, focusing on Cardiovascular Physiology, acting on the following subjects: angiogenesis, treinamento fisico, hipertensão, microcirculation and vegf. (Source: Lattes Curriculum)
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We previously demonstrated that physical preconditioning mitigates several side effects caused by chronic treatment with dexamethasone (DEX), including hypertension, arterial stiffening, and muscle atrophy. The mechanisms responsible for these responses are not yet fully elucidated. Recently, Irisin, a novel myokine induced by physical exercise, has gained visibility and has been consider…
Heart failure (HF) is a complex syndrome that affects 23 million people worldwide. The heart of HF patients presents cardiac remodeling, cardiac dysfunction and some of the implications involved in cardiac remodeling are determined mainly by inflammation. Thus, we hypothesized that treatment with dexamethasone (DEX) may identify cytokines which could be used as therapeutic target for card…
Hypertension is the main risk factor for cardiovascular diseases and has been considered an important health problem. We have previously shown that chronic dexamethasone (DEX) treatment determined hypertension; however, the responsible mechanisms are not completely elucidated. Since hypertensive individuals may have use DEX, is reasonable to think that DEX treatment would increase even mo…
Many factors appear to affect fluoride metabolism, however, there is limited and often contradictory evidence from the literature on the effect of exercise on fluoride metabolism. The primary aim of Dra Liane Azevedo visit is to collect data for a feasibility trial aiming to inform the design of a full trial targeting the effect of physical activity on fluoride metabolism. Dra Azevedo was…
(Only some records are available in English at this moment)
Cardiovascular diseases (CVD) are characterized by pathologies in the heart or circulatory system and present a high degree of morbidity and mortality. Arterial hypertension (AH), which is a risk factor for CVD, has been considered the main cause of premature death in the world. Associated with it, there is a change in vessel compliance causing arterial stiffness, and this parameter has b…
The use of dexamethasone (DEX), widely used in the clinic, is related to the loss of species diversity in the intestinal microbiota, which may determine a modulation in the host's immune response. On the other hand, the use of probiotics, as well as physical training, has been shown to influence the microbiota, however, its effects are still inconclusive. Therefore, the aim of the present…
It has been shown that intestinal microbiota has a great relationship with the immunity of an individual, achieving relevance in many cardiovascular diseases. The intestinal barrier function is essential to the control of pathogens entry into the vascular system. One of these pathogens is the lipopolysaccharide, a pro-inflammatory endotoxin. In the literature, a systemic inflammation stat…
(Only some records are available in English at this moment)
Dexamethasone (DEX) is used as anti-inflammatory and immunosuppressant drug. DEX treatment side-effects are several including muscle weakness, hypertension and microvascular rarefaction, which is attributed to an imbalance in angiogenesis and apoptotic signaling. DEX alters mitochondrial function in muscle cells but nothing is known of DEX effects in endothelial cells that could explain i…
| 1 / 1 | Ongoing grants |
| 10 / 8 | Completed research grants |
| 22 / 15 | Completed scholarships in Brazil |
| 2 / 1 | Completed scholarships abroad |
| 35 / 25 | All research grants and scholarships |
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