Paulo Henrique Braz da Silva

• Abstract

  Pre-exposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) involves the use of antiretroviral drugs to reduce the risk of HIV infection. Research has indicated an increase in the incidence of sexually transmitted infections (STIs), particularly bacterial ones, among individuals using PrEP. In this context, saliva emerges as a valuable biological fluid for identifying biomarker…

  Analysis of Salivary Biomarkers and the Oral Microbiome in Individuals Using Pre-Exposure Prophylaxis (PrEP) for Human Immunodeficiency Virus (HIV), AP.R

• Abstract

  COVID-19 is an emerging disease caused by the coronavirus SARS-CoV-2, which was first identified in China and then spread over other countries, thus being considered a pandemic by the World Health Organization (WHO). The disease is mainly characterised by fever, dry cough, myalgia and arthralgia, and may take a mild, moderate or severe form depending on the clinical involvement. Its diagn…

  Salivary biomarkers of COVID-19 and other viral respiratory infections, AP.R

• Abstract

  Background: Kaposi s sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8), is a gamma-herpesvirus and etiological agent of all forms of Kaposi sarcoma (KS). Saliva may play an important role in HHV-8 transmission in specific populations. Little is known about HHV-8 oral shedding pattern and the possible correlation with the HHV-8 serological profile and viremia…

  Prospective Study of Human Herpes Virus 8 (HHV-8) Oral Shedding, Viremia and Serological status among HIV Seropositive and Seronegative Individuals in Sao Paulo, Brazil, PUB.ART

• Abstract

  The study of tumor microenvironment is extremely important for understanding the individual immune response to neoplastic cells. Immunotolerance is a physiological mechanism by which the immune system self-regulate, by inhibiting the effector cell response, making it difficult for immune response initiation. This mechanism inhibits the development of autoimmune diseases, controlling and m…

  Evaluation of immunoregulatory microenvironment of oral premalignant lesions, squamous cell carcinomas and oropharyngeal carcinomas related to HPV or not., AP.R

• Abstract

  Syphilis, caused by Treponema pallidum, has been showing a marked increase globally and in Brazil, with a disproportionate impact on vulnerable populations. The oral cavity is an important site of clinical manifestation, especially in the primary and secondary stages, and plays a key role in early diagnosis. Saliva has emerged as a promising matrix for molecular diagnosis due to its simpl…

  Evaluation of saliva as a diagnostic tool for acquired syphilis: detection of treponemal DNA by qPCR, BP.IC

• Abstract

  A pre-exposure prophylaxis (PrEP) is indicated for populations vulnerable to human immunodeficiency virus (HIV) infection. In these groups, an increase in the incidence of sexually transmitted infections (STIs) is observed due to changes in sexual behavior after the initiation of antiretroviral therapy. Among these STIs, syphilis stands out as a significant public health problem worldwide…

  Analysis of salivary biomarkers and the oral microbiome/virome of patients diagnosed with syphilis, BP.DR

• Abstract

  COVID-19 is a disease caused by the SARS-CoV-2, with mild, moderate and severe forms, the latter of which can lead to death as a result of clinical impairment. Saliva has been presented as a less invasive alternative for detecting SARS-CoV-2, also presenting the possibility of analyzing inflammatory and immunological biomarkers that may be related to both the diagnosis and prognosis of th…

  Oral Shedding of Torque Teno Virus (TTV) in COVID-19 patients - possible biomarker of severity, BP.DR

• Abstract

  Saliva is the main route for transmission of several microorganisms, such as the Epstein-Barr virus (EBV), a well known human herpesvirus with lymphotropic characteristics. EBV is ubiquitous in humans, infecting approximately 90% of the global population. Its primary infection occurs mainly during childhood and may be asymptomatic. The virus is characterized by its latency and viral react…

  Epstein-Barr virus salivary shedding and serological status in pediatric patients with chronic kidney disease., BP.IC

(Only some records are available in English at this moment)