Brenda Paula Figueiredo de Almeida Gomes

• American Association of Endodontists - AAE25, AR.EXT

• Abstract

  The complex network that interconnects the sharing of genetic information between microbial communities is one of the main forces driving evolutionary processes. Through this powerful machinery operated by the mobiloma (i.e., set of mobile elements in a genome), microorganisms distribute genetic characteristics throughout ecosystems and living organisms. A significant example of this impr…

  Decoding the microbiota correlations of teeth indicated for endodontic retreatment and the complex interrelationship between mobiloma and resistome in oral site metagenomes, AP.R

• Abstract

  Over 15 million endodontic treatments (ET) are performed annually in the US and also in Brazil due to endodontic infections (EI). Such infections can cause signs and symptoms ranging from a mild discomfort to severe life-threatening infections, such as cellulitis, stroke or even death. This study aims to investigate the microbiomes present in different types of EI, and the levels of LPS, …

  Microbiomes and immunobiological aspects in endodontic infections, AP.TEM

(Only some records are available in English at this moment)

• Abstract

  The complex anatomy of the root canal system negatively interferes with the root canal disinfection process, especially in the apical third. In addition, microbial resistance, and its ability to adapt to environmental changes and grow in biofilm favors the permanence of these bacteria in root canals and dentinal tubules, being the main cause of failure of endodontic treatment. The objecti…

  Molecular evaluation of the apical microbiota of the root canal of teeth subject to cryogenic grinding, BP.MS

• Abstract

  Knowledge of endodontic biofilm as well as strategies to eradicate them from the root canal system is important for maintaining oral health and the teeth in the oral cavity. The use of multispecies biofilm models that mimic endodontic biofilms in situ allows for realistic and efficient investigations of new antimicrobial therapies, such as photodynamic therapy and the aid of chemical auxi…

  Evaluation of Photodynamic Therapy associated with Auxiliary Chemical Substances and Irrigants in the control of endodontic biofilms in Multispecies Biofilm Models, BP.MS

• Abstract

  The permanence of microorganisms in the root canal system (SCR) is the main etiological factor for the failure of endodontic treatment. The root canal microbiota, its cytotoxic profile and the host's immune system are the main responsible for the course of apical inflammation, as well as for the success and longevity of endodontic treatment. Considering the importance of persistent microo…

  INFLUENCE OF THE INFECTION TIME ON THE MICROBIOLOGICAL (BACTERIA AND FUNGI), CYTOTOXIC AND INFLAMMATORY PROFILE OF THE MICROBIAL COMMUNITY OF SECONDARY/PERSISTENT ENDODONTIC INFECTIONS, BP.DR

(Only some records are available in English at this moment)

• Abstract

  Little is known about periapical lesions microbiota, resistome, and mobilome. This study aims to collect all available data from next-generation sequencing of periapical lesions of endodontic origin, analyze them in silico for taxonomic and phylogenetic diversity, conduct a functional study of the microbial community, and assess the mobilome and resistome using bioinformatics tools. For t…

  Next-generation sequencing: in silico study of periapical lesion microbiome, resistome, and mobilome., BE.EP.PD

• Abstract

  Bacteria and their virulence factors play important role in the induction of pulpal and periradicular diseases. Biofilms are the main etiological factors in the pulp and periodontium inflammation. In cases of vital pulp tissues and associated periodontal disease, the bacteria from periodontal pockets are the primary source of infection to the dental pulp through pathways of infection (i.e…

  Epigenetic characterization in teeth with vital pulp tissues and associated periodontal disease before and after endodontic procedures, BE.EP.DR

• Abstract

  Bacteria and their products play important roles in the induction of pulpal disease. Biofilms from caries are the main etiological factor in pulpal inflammation. In cases of irreversible pulpitis, the pulp tissue presents accumulation of inflammatory mediators, influencing both destructive and reparative processes. Furthermore epigenetic control regulates the renewal and pluripotency of s…

  Clinical investigation of epigenetic modulations in dental pulp tissues with diagnosis of irreversible pulpitis, BE.EP.DR

(Only some records are available in English at this moment)