Sérgio Henrique Ferreira

• Abstract

  For the past 25 years, our group has been studying the physiopathological mechanisms involved in the inflammatory process. In order to continue doing so, in this project we seek to do translational research regarding inflammatory diseases, mainly rheumatoid arthritis, chronic pain and sepsis. All three topics will be investigated in an integrated stand: 1) mechanisms involved in recognizi…

  Mechanisms involved in the pathophysiology of rheumatoid arthritis, pain and sepsis, AP.TEM

• Abstract

  The acquisition of a flow cytometer will be of key importance to quantitatively and qualitatively maximize the scientific production of the USP Ribeirão Preto School of Medicine and of other schools on the campus. This equipment will allow the purification of different cell types, which are used in investigations of cell-cell interaction, host-parasite interaction and intracellular mechan…

  Acquisition of a flow cytometer for the specific separation of cells, AP.EMU

• Abstract

  Our project consists of 3 subprojects which investigate a) mechanisms involved in the genesis of chronic and acute inflammatory pain as well as the mechanisms involved in the effects of different analgesics; b) mediators involved in the migration of neutrophils in different models of immune inflammation; c) mechanisms involved in the failure of the migration of neutrophils to the site of …

  Mediators involved in the genesis of pain and the migration of leukocytes and in sepsis, AP.TEM

(Only some records are available in English at this moment)

• Abstract

  Plastic changes in sensory neurons that transmit nociception at central and peripheral level are responsible for the observed changes in the painful sensations during the inflammatory process. In fact, during inflammation or after the resolution occurs an increased excitability (sensitization) of a specific class of primary nociceptive neurons, due to the direct and indirect action of var…

  Role of afferent nociceptive fibers on the anti-hyperalgesic acupuncture effect in the model of acute, persistent and neuropathic hyper nociception, BP.PD

• Abstract

  Pain is considered a major social problem due to the difficulty of its controltherapeutic. The chronic pain of inflammatory origin are determined by injuryperipheral tissue and persistent activation of nociceptors, resulting in plasticityfunctional nervous system, changes in nociceptive sensitivity and expressionreceptors, ion channels, neurotransmitters and enzymes. In order to studypath…

  Research potassium channel voltage-dependent induction and maintenance of persistent and neuropathic hypernociception., BP.PD

• Abstract

  The International Association for the Study of Pain (IASP) defines pain as "an unpleasant sensory and emotional experience, associated with actual or potential tissue damage, or described in terms of such damage". When the pain is originated by an inflammation, it can be considered as the result of the interaction between the damaged tissue and peripheral nociceptive sensory neurons. On t…

  Investigation of the role of AP-1 transcription factor in the genesis of inflammatory and neuropathic hypernociception, BP.DR

(Only some records are available in English at this moment)