José Buratini Junior in research grants and scholarships supported by FAPESP.
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In vitro production of bovine embryos (IVP) has been applied to increase fertility and enhance genetic improvement in beef and dairy cattle despite its recognized low efficiency. In vitro maturation (IVM) is considered to be the main technical bottleneck of IVP in cattle. Current IVM protocols do not reflect the physiological conditions causing a mismatch between nuclear and cytoplasmic o…
In vitro production of bovine embryos (IVP) has been applied to increase fertility and enhance genetic improvement in beef and dairy herds, despite its recognized low efficiency. In vitro maturation (IVM) is considered to be the main technical bottleneck of IVP in cattle. Current IVM protocols do not reflect the physiological conditions and determine a mismatch between oocyte nuclear and …
We have recently demonstrated that oocyte derived FGFs stimulate cumulus expansion and alter the expression of regulatory genes. This proposal aims to assess the effects of FGFs 2, 10 and 17 and BMP15, as well as of the interactions FGFs/BMP15, on nuclear maturation, cumulus expansion, energetic metabolism, apoptosis, steroid production and expression of markers of developmental competenc…
(Only some records are available in English at this moment)
The oocyte in vitro maturation (IVM) is one of the main bottlenecks in vitro production of bovine embryos (IVP). The existing protocols for IVM do not reflect the physiological conditions and determine mismatch between nuclear and cytoplasmic maturation of the oocyte, thus compromising their fertility. Oocytes undergoing IVM are from follicles in different stages of development and this h…
The communication between the oocyte and surrounding somatic cells is essential for the differentiation of the cumulus-oocyte complex (COC). Oocyte secreted factors (OSFs), including fibroblast growth factors (FGF) and bone morphogenetic protein 15 (BMP-15), are important mediators in the communication between the oocyte and cumulus cells. FGF10 is expressed in the oocyte and its receptor…
Our group has recently demonstrated that fibroblast growth factors (FGFs) expressed by the oocyte stimulate cumulus expansion and regulate the expression of genes that regulate this process. This proposal aims to investigate in greater depth the functions of FGFs 2, 10 and 17 and BMP15 in the regulation of cumulus cells differentiation in cattle. To accomplish the overall objective, we wi…
(Only some records are available in English at this moment)
| 14 / 4 | Completed research grants |
| 24 / 6 | Completed scholarships in Brazil |
| 38 / 10 | All research grants and scholarships |
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