CV Lattes
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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Farmácia Bioquímica from Universidade de São Paulo (1996), master's at Ciências Farmacêuticas from Universidade de São Paulo (1999) and doctorate at Ciências Farmacêuticas from Universidade de São Paulo (2004). Has experience in Pharmacy, acting on the following subjects: biotransformation, atividade antimicrobiana, antimicrobial activity, biotransformação and aspergillus fumigatus. (Source: Lattes Curriculum)
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The studies proposed in this project on bioaccessibility, intestinal permeability and biotransformation of the bioactive constituents of new formulations of green propolis extracts are unprecedented and are expected to add value to these products of Brazilian biodiversity, bringing to light knowledge that will enable the filling of gaps aimed at developing of standardized medicines of nat…
The studies proposed in this project of bioaccessibility, intestinal transportation and biotransformation of diterpenes that are constituents of Copaifera sp. oil resins are new in this research field and it is hoped to bring knowledge that will contribute to the more efficient and safe use of this vegetal raw material. One of the major bottlenecks of Brazilian research is the lack of stu…
The human gastrointestinal tract possesses a great variety of aerobic and anaerobic bacteria which are capable of catalysing metabolic reactions of reduction, hydrolysis and heterocyclic ring rupture generating non-polar low molecular weight metabolites. Filamentous fungi are eukaryotic organisms and the enzymatic apparatus is similar to those of mammals producing polar high molecular wei…
The framing of this proposal in the Biota-FAPESP Program, BIOprospecTA subprogram, could prove to make a substantial contribution to the investigations which are currently underway among groups that make up the Network. In this project it is proposed to make available the extracts of culture media from the fungi and the derivatives isolated to be evaluated in the Network’s biotrials, as w…
Green propolis has high commercial and medicinal value and among its constituents is baccharin, one of the major compounds found in Baccharis dracunculifolia, the main botanical source of green propolis. Baccharin is notable for inhibiting the enzyme aldo-keto reductase 1C3, which in the mammary gland converts 4-androstane-3,17-dione into testosterone which can subsequently be converted t…
This project aims to investigate different cultivation conditions of five filamentous fungi in order to evaluate the influence of the culture medium and the incubation time on the biotransformation reactions of ent-polyalthic acid. It is also intended to select one or two filamentous fungi to biotransform this diterpene. The ent-polyalthic acid is a furan diterpene of labdane skeleton alr…
This project aims to investigate different cultivation conditions of five filamentous fungi in order to evaluate the influence of the culture medium and the incubation time on the biotransformation reactions of ent-hardwickiic acid. It is also intended to select one or two filamentous fungi to biotransform this diterpene acid. The ent-hardwickiic acid is the major constituent of the Copai…
(Only some records are available in English at this moment)
Pentacyclic triterpenes are widespread in the plant kingdom and they have been known for their remarkable bioactivities and health-promoting properties. Triterpenes occur largely in apple cultivars, which are among the most highly consumed fruits worldwide. Cultivars of Malus domestica Borkh possess different triterpene pattern, which could reflect in bioavailability and health-promoting …
| 1 / 1 | Ongoing grants |
| 3 / 3 | Completed research grants |
| 13 / 10 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 18 / 15 | All research grants and scholarships |
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