CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Instituto de Química (IQ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Química Bacharelado from Universidade Estadual de Campinas (1997), master's at Chemistry from Universidade Estadual de Campinas (2000) and ph.d. at Chemistry from Universidade Estadual de Campinas (2004). Has experience in Chemistry, focusing on Structure, Conformation and Stereochemistry, acting on the following subjects: agente antifúngico, reação aldólica, síntese total, policetídeos and agente imunossupressor. (Source: Lattes Curriculum)
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Terpenes and terpenoids represent the widest class of natural products found in nature. Despite their structural diversity, all terpenoids are biosynthesized from two chemically related molecules, namely 1- and 2-isopentenyl diphosphate. The isopentenyl diphosphates are joined in elongation reactions to form the linear precursors of all terpenoids. The action of terpene synthases then c…
Recent analysis of the genomic information from several Streptomyces strains has revealed an enormous abundance of gene clusters codifying enzymes from secondary metabolismo. The whole set of information infers that the capability to produce metabolites by Streptomyces and other actinobacteria is underestimated. As alternatives to tradicional screening methodologies, genomic tools represe…
(Only some records are available in English at this moment)
Recent analysis of the genomic information from several Streptomyces strains has revealed an enormous abundance of gene clusters codifying enzymes from secondary metabolismo. The whole set of information infers that the capability to produce metabolites by Streptomyces and other actinobacteria is underestimated. As alternatives to tradicional screening methodologies, genomic tools represe…
Among the most useful natural products, polyketides and non-ribosomal peptides share high molecular complexity and therapeutic activity. The production of these metabolites has been observed in many organisms, however, the cultivable actinobacteria are certainly the most prolific and versatile producers of such metabolites. In the case of actinobacteria, the assembly-line enzimology of mo…
(Only some records are available in English at this moment)
Actinobacteria are a phylum of gram-positive terrestrial or aquatic bacteria of significant importance for pharmaceutical industry and academic research due to their great potential to biosynthesize different types of natural products, including antibiotics and anticancer agents. Streptomyces is the largest bacterial genera from this phylum and several sequenced genomes have revealed an a…
A substantial number of valuable drugs available these days are based upon or inspired in natural products. Among the most useful natural products, polyketides and non-ribosomal peptides share high molecular complexity and therapeutic activity. Though the production of such metabolites is being observed from several organisms as bacteria, fungi, insects, dinoflagellates, mollusks and spon…
| 6 / 5 | Completed research grants |
| 12 / 7 | Completed scholarships in Brazil |
| 3 / 2 | Completed scholarships abroad |
| 21 / 14 | All research grants and scholarships |
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