Thais Martins de Lima Salgado

• Abstract

  Obesity is involved in the development of diseases associated with changes in lipid metabolism such as diabetes, dyslipidemias and cardiovascular diseases. Excess lipids stimulate inflammation, which is responsible for changes in insulin signaling. The search for new sources of treatment for the prevention of hyperglycemia and its complications has been intensifying all over the world, in…

  Modulation of metabolic and inflammatory parameters by the hydroalcoholic extract of Musa cavendishii in high fat diet obesity, AP.R

• Abstract

  Sepsis, SIRS and septic shock are responsible for 30-45% of death in ICU. The treatment is based only in hemodynamic support and source control. The cytokines induces the release of many others inflammatory mediators, as for instance reactive oxygen species, and nitric oxide. Toll-like (TLR) inhibitors, antinflammatory cytokines and changes in TLR signaling are the mechanism that control …

  Sepsis and LPS tolerance - LPS tolerance role on oxidative stress and mithocondrial function, proteic nytrosilation and DNA damage, AP.TEM

• Abstract

  Obesity is involved in the development of diseases associated with disturbed lipid metabolism such as diabetes, dyslipidemia and cardiovascular disease. Excess lipids stimulate inflammation via activation of receptors such TLR4, leading to changes in insulin signaling. Furthermore, ectopic fat accumulation observed in obesity generates metabolites that can also interfere with intracellula…

  Acyl-carnitines as markers of intermediate metabolism in morbidly obese individuals undergoing a clinical treatment for weight loss, AP.R

(Only some records are available in English at this moment)

• Abstract

  Obesity and atherosclerosis are diseases found in several patients simultaneously. The literature suggests that in addition to dyslipidemia, chronic inflammation observed in obesity is related to the activation of macrophages in the vessels and the development of atherosclerosis. However no studies investigating whether the metabolic changes (storage and hydrolysis of triacylglycerol and …

  Characterization of adipose tissue inflammation in LDL receptor knockout mice, BP.IC

• Abstract

  Sepsis is a disease with high incidence in the ICU, causing high costs to public and private health sectors. Despite the development of new antibiotics and improved intensive care measures, the mortality rate has not changed in the last two decades. Besides the known problems in treating this disease, currently there is as increasing incidence of obesity in the general population, includi…

  Effect of obesity in lung inflammation and remodeling in sepsis, BP.IC