Rita Cássia Menegati Dornelles

• Abstract

  The important involvement of the suprachiasmatic nucleus (SCN) and the activity of vasopressinergic neurons in maintaining therhythmicity of the female reproductive system depends on the mRNA transcription-translation feedback loops. Therefore, circadianclock function, like most physiological processes, is involved in the events that determine reproductive aging. This study describesthe c…

  Atividade vasopressinérgica do núcleo supraquiasmático e expressão de RNAm dos genes do relógio no eixo hipotálamo-hipófise-gonadal no envelhecimento feminino, PUB.ART

• Abstract

  The objective of this study is to identify whether oxytocin (ot) contributes to the reduction of osteopenia in the femoral neck of rats in periestropause. Animals in irregular estrous cycles received two NaCl injections (0.15 mol/L) or OT (134 ¼g/kg) over a 12-h interval, and after thirty-five days without treatments, the biological sample collection was performed. the oxytocin group (ot)…

  Oxytocin and bone quality in the femoral neck of rats in periestropause, PUB.ART

• Abstract

  Aging is the result of cumulative, progressive, intrinsic, and deleterious functional and structural changes that usually begin to manifest in reproductive maturity, although their genesis may have been earlier. The reproductive function in female organisms is controlled by both the hypothalamic-pituitary-gonadal axis and the biological clock, both of which are fundamental for the outgrow…

  Analysis of the clock proteins in the hypothalamic-pituitary-gonadal axis and the relation with female reproductive senescence, AP.R

(Only some records are available in English at this moment)

• Abstract

  Changes in the plasma secretion of gonadal steroids that characterize stages of the female life cycle also interfere with the bone structure of these organisms, altering the process of bone remodeling and repair. The imbalance in bone microarchitecture results in osteopenia and osteoporosis, whose decrease in bone mass makes the bone structure fragile and susceptible to fracture. The fail…

  Treatment effect with oxytocin in bone consolidation of rats during the periestropause and estropause, BP.IC

• Abstract

  The life stages of human beings are marked by cycles understood as childhood, adolescence, adulthood and old age. Functional capacity and homeostatic control mechanisms act and provide interaction with the environment, with characteristics specific to each cycle. The transition from adulthood to old age in women is marked by hormonal changes that trigger and enhance reproductive senescenc…

  Analysis of the antioxidant and autophagic system in the Wistar female hippocampus during reproductive senescence, BP.IC

• Abstract

  In women, deficiency of the reproductive hormone during menopause leads to an imbalance between resorption and bone formation, contributing to the decrease in tissue quality and favoring the incidence of osteoporosis and fractures. However, the reduction in bone quality and mass in the skeletal sites of the elderly person can result in delay or not consolidate the fracture. In addition, t…

  Effect of low-intensity ultrasound on bone healing after unilateral femur fracture in naturally aged rats, BP.IC

(Only some records are available in English at this moment)

• Abstract

  During female senescence, hypothalamic-pituitary-gonads display progressive reduction in their functions resulting in endocrine deficiency. Plasma concentrations of estrogen (E2) influence the mechanisms responsible for the maintenance of muscle mass, possibly through direct action of the E2. The hormone replacement therapy (HRT) has a protective effect on the maintenance of lean body mas…

  Estrogen and strength training relationship upon IGF-1, PGC-1±4 pathways, miRNAs and sirtuins on skeletal muscle of senile female rats, BE.EP.DR