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Rafael Victorio Carvalho Guido

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Universidade de São Paulo (USP). Instituto de Física de São Carlos (IFSC)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Associate professor at the Physics Institute of São Carlos (IFSC) of the University of São Paulo (USP). He received his PhD in biomolecular physics from the University of São Paulo and the University of Marburg in 2008, and completed two years of postdoctoral work in medicinal chemistry and structural biology at the University of São Paulo. He is a specialist in structure-based drug design and in the integration of computational and experimental methods. His research is focused on the structural elucidation of relevant molecular targets and the application of this knowledge toward the discovery and development of new drugs and agrochemicals for human and plant diseases. He is the coordinator of a Young Research Grant from Serrapilheira Institute, whose scientific approach consists of the use of a variety of advanced methods for agrochemical and drug design. He has published 72 scientific papers and 6 book chapters. He is associated investigator of the Center for Research and Innovation in Biodiversity and Drugs (CIBFar-CEPID-FAPESP). He was the Chair (2016-2018) and Vice-Chair (2014-2016) of the Medicinal Chemistry Division of the Brazilian Chemical Society. Currently, he was an Affiliated Member of The World Academy of Sciences (TWAS) (2105-2020) and an Young Scientist of the World Economic Forum (WEF). (Source: Lattes Curriculum)

Research grants
Scholarships in Brazil
Scholarships abroad
FAPESP support in numbers * Updated February 20, 2021
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Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (6)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Data from Web of Science

BUENO, RENATA; DAWSON, ALICE; HUNTER, WILLIAM N.. An assessment of three human methylenetetrahydrofolate dehydrogenase/cyclohydrolase-ligand complexes following further refinement. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, v. 75, n. 3, p. 148-152, . Web of Science Citations: 0. (16/16038-5)

SILVEIRA, FLAVIA F.; DE SOUZA, JULIANA O.; HOELZ, LUCAS V. B.; CAMPOS, VINICIUS R.; JABOR, VALQUIRIA A. P.; AGUIAR, ANNA C. C.; NONATO, M. CRISTINA; ALBUQUERQUE, MAGALY G.; GUIDO, RAFAEL V. C.; BOECHAT, NUBIA; et al. Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 209, . Web of Science Citations: 0. (17/26679-0, 13/07600-3)

DE SOUZA, GUILHERME EDUARDO; BUENO, RENATA VIEIRA; DE SOUZA, JULIANA OLIVEIRA; ZANINI, CAMILA LIMA; CRUZ, FABIO CARDOSO; OLIVA, GLAUCIUS; CARVALHO GUIDO, RAFAEL VICTORIO; CAMPOS AGUIAR, ANNA CAROLINE. Antiplasmodial profile of selected compounds from Malaria Box: in vitro evaluation, speed of action and drug combination studies. Malaria Journal, v. 18, n. 1, . Web of Science Citations: 0. (16/09772-4, 13/07600-3, 15/18192-9)

CHUNG, MAN-CHIN; GUIDO, RAFAEL VICTÓRIO CARVALHO; MARTINELLI, TATIANE FAVARATO; GONÇALVES, MARINEI FERREIRA; POLLI, MICHELLE CARNEIRO; BOTELHO, KATIA CIRLENE ALVES; VARANDA, ELIANA APARECIDA; COLLI, WALTER; MIRANDA, M. TERÊSA M.; FERREIRA, ELIZABETH IGNE. Synthesis and in vitro evaluation of potential antichagasic hydroxymethyinitrofurazone (NFOH-121): A new nitrofurazone prodrug. Bioorganic & Medicinal Chemistry, v. 11, n. 22, p. 4779-4783, . (95/04562-3, 01/01192-3)

MARTELLI, LORENA S. R.; VIEIRA, LUCAS C. C.; PAIXAO, MARCIO W.; ZUKERMAN-SCHPECTOR, JULIO; DE SOUZA, JULIANA O.; AGUIAR, ANNA CAROLINE C.; OLIVA, GLAUCIUS; GUIDO, RAFAEL V. C.; CORREA, ARLENE G.. Organocatalytic asymmetric vinylogous 1,4-addition of alpha,alpha-Dicyanoolefins to chalcones under a bio-based reaction media: Discovery of new Michael adducts with antiplasmodial activity. Tetrahedron, v. 75, n. 25, p. 3530-3542, . Web of Science Citations: 1. (14/50249-8, 13/07600-3, 17/26679-0)

GARCIA, MARIANA L.; DE OLIVEIRA, ANDREW A.; BUENO, V, RENATA; NOGUEIRA, VICTOR H. R.; DE SOUZA, GUILHERME E.; GUIDO, RAFAEL V. C.. QSAR studies on benzothiophene derivatives as Plasmodium falciparum N-myristoyltransferase inhibitors: Molecular insights into affinity and selectivity. Drug Development Research, . Web of Science Citations: 0. (13/04737-8, 13/07600-3, 15/07005-3, 15/21272-4)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

GUIDO, Rafael Victorio Carvalho. Planejamento de inibidores da enzima gliceraldeído-3-fosfato desidrogenase de Trypanosoma cruzi: biologia estrutural e química medicinal. Tese (Doutorado) -  Instituto de Física de São Carlos.  Universidade de São Paulo (USP).  São Carlos.  (02/12680-1

BUENO, Renata Vieira. Estudos estruturais e funcionais da enzima N5, N10 - metilenotetrahidrofolato-desidrogenase-ciclohidrolase de Xanthomonas albilineans aplicados à descoberta de candidatos a inibidores para o tratamento da escaldadura das folhas. Tese (Doutorado) -  Instituto de Física de São Carlos.  Universidade de São Paulo (USP).  São Carlos.  (13/04737-8

SOUZA, Guilherme Eduardo de. Descoberta de derivados de hidrazinobenzimidazol como inibidores de Plasmodium falciparum: Síntese orgânica, atividade biológica e relação estrutura-atividade. Dissertação (Mestrado) -  Instituto de Física de São Carlos.  Universidade de São Paulo (USP).  São Carlos.  (16/09772-4

GARCIA, Mariana Lopes. Estudos computacionais da enzima N-miristoiltransferase de Plasmodium falciparum e seus inibidores como candidatos a agentes antimaláricos. Dissertação (Mestrado) -  Instituto de Física de São Carlos.  Universidade de São Paulo (USP).  São Carlos.  (15/21272-4

MALUF, Fernando Vasconcelos. Estudos estruturais e de química medicinal aplicados às enzimas da via glicolítica de protozoários: enolase de Plasmodium falciparum e gliceraldeído-3-fosfato desidrogenase de Trypanosoma cruzi. Tese (Doutorado) -  Instituto de Física de São Carlos.  Universidade de São Paulo (USP).  São Carlos.  (10/10050-7

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