CV Lattes
ORCID
Google Scholar Citations
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Faculdade de Medicina from Universidade Federal do Rio Grande do Sul (1980), master's at Physiology from Universidade Federal do Rio Grande do Sul (1985) and ph.d. at Physiology from Universidade de São Paulo (1989). Has experience in Physiology, focusing on Endocrine Physiology, acting on the following subjects: glut4, glut 4, diabetes, obesity and diabetes mellitus. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| More itemsLess items |
| TITULO |
| Articles published in other media outlets ( ): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Diabetes Mellitus (DM) and its chronic complications are the greatest public health problem. It is a must to develop approaches that help to control glycemia and to reduce the incidence of complications. Target territories to develop complications, which will be focused on in this proposal, include kidney, cardiovascular system, brain (Alzheimer's Disease also referred to as DM3) and live…
(Only some records are available in English at this moment)
Diabetes mellitus (DM) and its chronic complications are the major public health problems, making it essential to improve measures to improve glycemic control and reduce the incidence of complications such as dyslipidemia. They are targets of the development of complications, addressed in the present proposal the brain (Alzheimer's Disease, DM3), more precisely the cortex. This proposal h…
Type 2 diabetes mellitus (T2DM) etiopathogeny and pathophysiology are highly related to insulin resistance, a process in which reduced expression of the glucose transporter GLUT4 plays a key role. Recently, epigenetic regulation of several proteins has been related to diabetes; however, nothing is known regarding microRNAs participation on the GLUT4 content reduction in skeletal muscle of…
Epidemiological studies have shown that diabetes mellitus and obesity are risk factors for the genesis and progression of Alzheimer's disease. In the last decade, studies have demonstrated the existence of brain insulin resistance in Alzheimer's disease (AD) patients, suggesting that a reduced glucose uptake to neuronal cells could be a key element in the onset and progression of neurodeg…
(Only some records are available in English at this moment)
Estrogen (E2) regulates the angiogenesis in different tissues and participates on the pathophysiology of the obesity and diabetes. In fat cells, E2 increases the expression of glucose transporter GLUT4 (encoded by Slc2a4 gene) as well as glucose uptake, increasing insulin sensitivity. It is known that E2 is able to modulated vascular endothelial growth factor (VEGFA) expression, which is …
Type 2 diabetes mellitus (T2DM) is characterized by disruption in glycemic homeostasis, involving impaired insulin-induced glucose disposal. For that, reduced glucose transporter GLUT4, encoded by Slc2a4 gene, plays a fundamental role. Recent studies have proposed that estradiol (E2) is able to modulate Slc2a4 expression, through its nuclear receptors, the estrogen receptors ESR1/ESR2. It…
| 1 / 0 | Ongoing grants |
| 15 / 9 | Completed research grants |
| 53 / 18 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 71 / 29 | All research grants and scholarships |
| Associated processes | |