Professor and researcher at the Federal University of São Paulo (UNIFESP), working in the Atom to Cell Module, Biochemistry discipline. Currently serves as Deputy Director of the Technological and Social Innovation Agency (Agits), and has previously acted as coordinator and advisor of the Graduate Program in Bioproducts and Bioprocesses, as well as coordinator of the Specialization Course in Biotechnology at UNIFESP. Holds a bachelors degree (2002), a masters degree (2005), and a PhD (2009) from the Federal University of São Carlos (UFSCar). Served as a substitute professor in Anatomy and Pathology at the same institution. Completed a sandwich PhD in Biotechnology and Cell Biology at the Vrije Universiteit Amsterdam (Amsterdam, the Netherlands, 2008) and a postdoctoral fellowship in Integrative Bone Tissue Biology at Université Jean Monnet Université de Lyon (Saint-Étienne, France, 20112013). Holds a diploma in Animal Experimentation from Université Paris V (Paris, 2013). Also worked as a contracted researcher at the French Alternative Energies and Atomic Energy Commission (CEA, France), within the framework of the European project RISK-IR, involving 10 institutions from 7 European countries (20132014). Returned to Brazil through the Young Talent Attraction program of the National Council for Scientific and Technological Development (CNPq). Has experience in clinical studies involving women with osteoporosis, as well as in experimental in vitro and in vivo studies investigating the integrative biology of bone tissue, its mineralized matrix, and the bone marrow microenvironment. Also conducts studies analyzing the osteogenic potential of synthetic and natural biomaterials, with a focus on the development of innovative bioproducts. Research interests include tissue engineering (bone and skin), stem cells derived from different adult tissues, mechanical stress, physical resources, and cytogenotoxic agents. (Source: Lattes Curriculum)
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In recent years, hydroxyapatite (HA) derived from fish bones and scales has emerged as a safe alternative to replace synthetic and bovine HA in applications related to bone tissue engineering, as similar chemical properties have been achieved through simple and economical methods. Furthermore, fish are abundant in the environment, and the utilization of their by-products is suitable for b…
The rich biological diversity of marine ecosystems makes them abundant in bioactive compounds favorable to the development of innovative biotechnological products. Several studies have shown, for example, that the biosilica extracted from marine sponges has osteogenic properties and our group have recently demonstrated that it may even have superior osteoinductive effects than those of th…
In recent years, hydroxyapatite (HA) extracted from fish waste has emerged as a sustainable, safe, and biologically compatible alternative for applications in bone tissue engineering. Derived from species such as croaker (Micropogonias furnieri), this biogenic HA exhibits a chemical composition and crystalline structure similar to human bone, while aligning with the principles of circular…
The hydroxyapatite (HA) is a bioceramic widely used in bone tissue engineering due to its similarity to the mineral phase of bones. Obtaining HA from fish waste represents a sustainable alternative for the production of this material. Additionally, Spirulina biomass has been studied for its bioactive properties that may promote osteogenesis. This study aims to evaluate the biological res…
With the increase in cases of bone fractures and the difficulty of regenerating critical defects,the tissue engineering has been applied to the development of new therapeutic interventions.The richbiological diversity of marine ecosystems makes them abundant in bioactive compounds favorable to thedevelopment of innovative biotechnological products. Several studies have shown that the bios…
A rica diversidade biológica dos ecossistemas marinhos os tornam abundantes em compostos bioativos propícios ao desenvolvimento de produtos biotecnológicos inovadores. Diversas pesquisas comprovaram, por exemplo, que a biosílica extraída de esponjas marinhas possui propriedades osteogênicas e nosso grupo recentemente demonstrou que os seus efeitos osteoindutores podem ser até mesmo superi…
With the increase in life expectancy that has been occurring in recent years, it is also expected to increase the appearance of common diseases of aging, among them osteoporosis, which along with other causes such as traffic accidents, contribute to the increased incidence of bone fractures. In this context, the proper treatment for the consolidation of these lesions may require the use o…
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Hyaline cartilage is crucial for the proper functioning of the knee joint, as it provides the necessary support for movement, stability and lubrication in key compartments of the joint. Its avascular and aneural characteristics make it susceptible to mechanical damage caused by injury, trauma, inflammation and degenerative conditions such as osteoarthritis. As a result, joint diseases hav…
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