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Secretaria da Saúde (São Paulo - Estado). Coordenadoria de Serviços de Saúde (CSS). Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira (ICESP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Matheus Ferracini in research grants and scholarships supported by FAPESP.
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The PAF receptor (PAF-R) is a G protein-coupled receptor present in leukocytes, endothelial cells and some types of tumor. Besides pro-inflammatory effects, PAF-R activation induces suppressor phenotype in leukocytes and systemic immunosuppression. Further, several authors showed that PAF-R promotes tumor growth and suggest that this is due to suppression of immune response and promotion …
Myeloid-derived suppressor cells (MDSC) comprise a group of cells that modulates immune response by inducing Treg generation, by producing TGF-beta, IL-10, etc. We showed that apoptotic cells-induced regulatory profile in macrophages is dependent on platelet-activating factor receptor (PAFR), and that PAFR contributes to tumor growth. Travers and col described that the promotion of tumor …
| 4 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 5 / 3 | All Scholarships |
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