Ita Pfeferman Heilberg

• Abstract

  Obesity has become a major public health problem worldwide, because of conferring a higher risk of developing cardiovascular diseases, type 2 diabetes mellitus, metabolic syndrome, arterial hypertension and renal diseases such as nephrolithiasis and glomerulopathies. Moreover, obesity affects the bone mineral metabolism, in an important way. Although increased body weight had been traditi…

  The Relationship between bone mineral metabolism and autonomic nervous system in obesity, AP.R

• Abstract

  Idiopathic Hypercalciuria (IH) is the most common metabolic abnormality among lithiasics patients, accounting for up to 40% of cases of nephrolithiasis. An inverse association between calcium excretion and Bone Mineral Density (BMD) has been demonstrated in both stone formers and non-stone formers. Several studies have found decreased trabecular and cortical BMD among IH patients. Bone …

  Evaluation of bone microarchitecture and finite element and their association with anthropometric, densitometric biochemical and hormonal parameters in hypercalciuric nephrolithiasis patients, AP.R

• Abstract

  Regenerative medicine, defines a new concept related to strategies to restore damaged tissue or accelerate tissue repair after injury. The tissue reconstruction and repair, however, constitute a major challenge of the current biomedical research since the cellular mechanisms underlying tissue reconstruction and repair are still poorly understood and largely unknown. Multipotent stem cells…

  MicroRNAs, extracellular vesicles and stem cells: physiology, pathophysiological role and therapeutic potential in renal diseases, AP.TEM

(Only some records are available in English at this moment)

• Abstract

  INTRODUCTION: Primary Hyperparathyroidism (PHTP) is an endocrine disorder characterized by the concomitant elevation of serum calcium and parathyroid hormone (PTH) levels resulting from autonomous production by the parathyroid glands. Its main clinical features are nephrolithiasis and reduced bone mineral density. OBJECTIVE: To retrospectively evaluate clinical and laboratory characterist…

  Clinical and laboratory findings in patients with Primary Hyperparathyroidism., BP.IC

• Abstract

  Bariatric surgery (BS) has become the most common surgical intervention as a means to lose weight. However, one of its long-term complication is an increased risk of nephrolithiasis, mainly due to elevation in urinary oxalate (Ox), whose underlying mechanisms have not been determined yet. In a recent experimental study, BS-induced fat malabsorption has been shown to modify the colonic per…

  Evaluation of ocludin e ZO-1 proteins expression in bariatric surgery rat intestine fragments, BP.IC

• Abstract

  Autosomal Dominant Polycystic Kidney Disease (ADPKD), the most common monogenic renal disease, is responsible for 4.4 - 10% of hemodialysis patients. The clinical manifestations appear over the 5th decade of life and most patients undergo end-stage renal disease around 60 years old. This disease is characterized by multiple cysts formation and growth, resulting in progressive cyst expansi…

  Evaluation of fibrosis factors and microRNAs in the progression of the polycystic renal disease in a PKD1 deficient murine model, BP.PD

(Only some records are available in English at this moment)