Abstract
Exosome is a multiprotein complex responsible for processing and degradation of many types of RNAs in eukaryotic cells. This complex localizes both to the nucleus and cytoplasm. The exosome complex has two catalytic subunits: Rrp6, found only in the nucleus, and Rrp44, found in the nucleus and in the cytoplasm of Saccharomyces cerevisiae. The Rrp44 is an essential protein of the RNase II …