graduation at Química bacharelado com ênfase em química tecnológica from Universidade Federal Fluminense (2016). , acting on the following subjects: benzoxazolamides, etenoditioacetais, synthesis, síntese and benzoxazóis. (Source: Lattes Curriculum)
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Malaria is a lethal parasitic disease with worldwide prevalence and despite investments in the search for new drugs, a high mortality rate is observed. The great structural diversity of natural products as well as their potent biological activities makes them attractive molecules for the discovery and development of new drugs. Among the microorganisms, fungi of different origins have been…
Tropical diseases caused by parasites, such as Chagas Disease, Sleeping Sickness and Leishmaniasis, affect thousands of people every year. Due to a lack of efficient drugs for the treatment, these diseases cause the death of many infected.Among the organic compounds that attract the attention of medicinal chemistry, fused nitrogen heterocycles, such as pyrroloquinazolines and pyrroloisoqu…
Neglected diseases caused by protozoan Leishmania and Trypanosoma affect thousands of people every year, in most cases leading to death of many infected. Most of drugs used on treatment of these diseases are not efficient in chronic stages of them and normally exhibit high toxicity. Therefore, the study to obtain new compounds that exhibit antiparasital activity is very important. In this…
Aminonitriles are important intermediates in organic synthesis, since this structure can be used as a building block on the synthesis of several heterocyclic compounds. The versatile reactivity of these structures is due to the presence of an acidic hydrogen in the ±-position of amino and cyano groups. The most common form of employing these intermediates is through reaction of the ±-amin…
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