Felipe Antunes Calil

Felipe Antunes Calil is a Brazilian researcher with a distinguished academic and professional trajectory in the fields of chemistry, biochemistry, molecular and structural biology. He holds a Bachelor's degree in Technological Chemistry from the Centro Universitário da Fundação Educacional de Barretos (2011), a Master's degree in Chemistry from the University of São Paulo (USP) in Ribeirão Preto (2014), and a Ph.D. in Biological Chemistry and Physics from the Faculty of Pharmaceutical Sciences of Ribeirão Preto (USP, 2019). During his Master's and Ph.D., he worked with enzymes from organisms that cause neglected diseases such as Leishmaniasis, Schistosomiasis, and Chagas Disease, using advanced techniques such as cloning, recombinant expression, protein purification, and biophysical and crystallographic methods. He completed a postdoctoral fellowship at the Ludwig Institute for Cancer Research at the University of California, San Diego (UCSD), where he contributed to the elucidation of DNA mismatch repair mechanisms, exploring Exo1-independent pathways (https://rdcu.be/cSDUn). Currently, he works in the field of ClpP ligand discovery, a bacterial protease, as a strategy to combat antibiotic-resistant bacteria. His current research involves the identification and characterization of molecules that modulate ClpP activity, aiming to develop new therapies for multidrug-resistant bacterial infections. He has published several articles in high-impact journals, with over 500 citations, and serves as an editorial member and reviewer for scientific journals such as Discovery Applied Sciences, International Journal of Biological Macromolecules, Biochemistry, and Journal of Medicinal Chemistry. (Source: Lattes Curriculum)