Abstract
The aim of this project is to describe the application plan of the School of Pharmaceutical Sciences for the grant related to the "Reserva Técnica Institucional" of Fapesp. (AU)
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Ricardo Luiz Nunes de Souza
CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Ciências Farmacêuticas (FCFAR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
PhD in Psychobiology (University of São Paulo). He has expertise in Behavioral Pharmacology at Institute of Pharmacology, University of Zurich, Switzerland (1989) and University of Leeds, UK (1999). Full Professor of Pharmacology at School of Pharmaceutical Sciences, São Paulo Sate University (UNESP). Head of the Joint Graduate Program in Physiological Sciences (UFSCar-UNESP, 2013-2017). Member of the editorial board of the Acta Neurobiologiae Experimentalis. Nunes-de-Souza was also President of the Brazilian Society for Neurosciences and Behavior (2014-2017). Since 2018 is head of the scientific committee of the III FALAN Congress (Federation of Latin American and Caribbean Neuroscience Societies). Dr. Nunes-de-Souza was chosen by the CNPq Deliberative Council (CD) to form the Advisory Committee on Biophysics, Biochemistry, Pharmacology, Physiology and Neurosciences (CA-BF), with a three-year term of office from 01/07/2019 to 30/06/2022. Principal line of research: Neurobiology of pain and defense reactions in rodents. (Source: Lattes Curriculum)
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Research grants
- Project for the Reserva Técnica Institucional of the School of Pharmaceutical Sciences - UNESP/Araraquara, AP.RT.INST
- Project for the Reserva Técnica Institucional of the School of Pharmaceutical Sciences - UNESP/Araraquara, AP.RT.INST
Abstract
The aim of this project is to describe the application plan of the School of Pharmaceutical Sciences for the grant related to the "Reserva Técnica Institucional" of Fapesp. (AU)
- Project for the Reserva Técnica Institucional of the School of Pharmaceutical Sciences - UNESP/Araraquara, AP.RT.INST
Abstract
The aim of this project is to describe the application plan of the School of Pharmaceutical Sciences for the grant related to the "Reserva Técnica Institucional" of Fapesp. (AU)
(Only some records are available in English at this moment)
Scholarships in Brazil
- Investigation of the involvement of sex differences in CRFergic neurotransmission of the medial prefrontal cortex and BNST over anxiety and corticosterone levels in mice exposed to social defeat stress., BP.MS
Abstract
Anxiety is characterized by an emotional response to aversive stimuli, even when they are absent from the immediate environment. Anxiety disorders are globally prevalent, with females exhibiting a higher incidence compared to males, presumably because of physiological, genetic and social factors, such as psychosocial stress. The Chronic Social Defeat Stress model (CSDS) enables research r…
- Assesment of the Impact of Acute and Chronic Psychosocial Stress on Plasma Corticosterone Levels in Female and Male Mice, BP.IC
Abstract
Stress is a recognized risk factor for the development of neuropsychiatric diseases. The effects produced by stress can be experimentally investigated through the animal model of social defeat witness, especially in behaviors associated with anxiety and depression. However, the behavioral and hormonal effects underlying stress, such as sex, type of stressor, frequency, and exposure to new…
- ASSESMENT OF THE ROLE OF THE AMYDALOID COMPLEX, DORSAL HIPPOCAMPUS AND THE INFLUENCE OF GENDER AND AGE ON RESPONSES RELATED TO DEPRESSION IN MICE SUBMITTED TO THE STRESS OF WITNESSING SOCIAL DEFEAT, BP.MS
Abstract
Human beings are exposed to different sources of stress. Currently, the most common form of stress comes from the social environment, whether experienced directly or through observation. Chronic exposure to stress is related to the development of psychiatric illnesses such as depression and anxiety, however, the effect of stress has been shown to be differential and dependent on variables…
- INFLUENCE OF SEX DIFFERENCES AND OXYTOCINERGIC NEUROTRANSMISSION ON THE CHRONIC PAIN SENSORIAL AND AFFECTIVE COMPONENTS IN MICE SUBMITTED TO SOCIAL ISOLATION, BP.IC
Abstract
Chronic pain conditions have a huge worldwide prevalence, affecting women in a higher proportion. In addition, there is a relevant correlation between chronic pain and psychopathologies, triggering progressive mood changes sex-dependent, such as anxiety and depressive-like behaviors. From the neuro-functional aspect, oxytocin is an important modulator of behavioral and neurobiological res…
- Local neurochemical mechanisms involved in the control of cardiovascular responses to restraint stress by different regions of the posterior portion of the insular cortex in rats, BP.MS
Abstract
The survival of species in the face of aversive events or stressors depends on a coordinated set of physiological and behavioral responses. The insular cortex (IC) is a cortical structure that has been implicated in the integration and processing of limbic information in humans and animals. In fact, it has been reported an involvement of the iC in the generation of physiological and behav…
(Only some records are available in English at this moment)
Scholarships abroad
- Evaluation of the role of anterior insular cortex neuronal mechanisms in modulating memory detailedness, BE.EP.DR
Abstract
It is well established that stressful or emotionally arousing events are remembered better than neutral events. However, much less is known to what extent they also impact the quality of these strengthened memories. As stress-induced changes particularly the quality of memory are thought to be a driving force in stress-related mental disorders, it is of critical importance to understand h…
- Evaluating the consequences of psychosocial stress exposure to the functional lateralization of the media prefrontal cortex: a morphological and functional approach, BE.EP.PD
Abstract
Recently, the importance of the functional lateralization of the medial prefrontal cortex (mPFC) in modulating the emotional responses to aversive stimuli has been gaining attention. Results involving the manipulation of the mPFC activity, specifically the prelimbic (PrL) mPFC, suggest that the chronic stress exposure induce long term changes in this region, decreasing the left mPFC (LmPF…
- Effects of corticotrophin releasing factor (CRF) overexpression and Crf1 and CRF2 receptors knockout within limbic structures on defensive behavior in mice: influence of acute and chronic stress, BE.EP.PD
Abstract
Corticotrophin releasing factor (CRF) is an important coordinator of neuroendocrine, autonomic, behavioral and immunological responses to stressful stimuli. CRF is able to modulate several behaviors, such as defensive reactions, and its malfunction in humans is associated with psychiatry disorders related to stress, including anxiety and affective disorders. Most of the CRF behavioral eff…
Total / Available in English
| 10 / 7 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 28 / 15 | Completed scholarships in Brazil |
| 4 / 3 | Completed scholarships abroad |
| 44 / 27 | All research grants and scholarships |
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