José Clóvis do Prado Júnior

• Abstract

  Despite all the scientific advances in recent decades in order to unravel the host's immune processes and the fparasite evasion, Chagas disease is still a major public health problem. Life expectancy in Brazil has increased every year and this growth allows the emergence of an elderly population at risk of contracting Chagas disease. The immune response as well as most of the physiologica…

  Melatonin and senescence : study the modulation of the immune system during experimental infection with Trypanosoma cruzi., AP.R

• Abstract

  As a result of Chagas' disease being a serious public health problem, the search and identification of molecules with potential therapeutic actions and understanding of the mechanisms involved in modulating the immune response by the administration of pharmacologically active substances in experimental models infected with Trypanosoma cruzi has contributed considerably in the investigatio…

  Evaluation of melatonin, lycopene and benznidazole supplementation during experimental Chagas Disease, AP.R

• Abstract

  The modulation of immune responses against the administration of pharmacologically active in animal models infected with Trypanosoma cruzi has contributed significantly in investigations of new therapies for Chagas disease. Zinc is a trace element of extreme importance for the maintenance of immune functions. Previous studies have demonstrated the stimulatory action of zinc on host immuni…

  Immunomodulatory actions of zinc and prolactin during the course of experimental Trypanosoma cruzi infection, AP.R

(Only some records are available in English at this moment)

• Abstract

  Despite all the scientific advances in recent decades in order to unravel the host immune processes and the circumvention of the parasite, Chagas disease is still a major public health problem, affecting approximately 20 million people throughout Latin America. The corresponding Brazil for about 3,5 million patients with Chagas disease. Demographic projections estimate an increase in the …

  Immunosenescence: impact against the experimental infection with Trypanosoma cruzi, BP.DR
• Potential therapeutic actions of the melatonin-meloxicam association on the chagasic myocardite in wistar rats infected with the y strain of T. cruzi., BP.DR
• Dehydroepiandrosterone: the treatment effects with its metabolites (DHEA-sulfate, androstenediol e androstenetriol) and benzonidazol associations during the acute phase of experimental infection by different strains of Trypanosoma cruzi, BP.PD