Has bachelor's degree in Biology (CEUSNP, 2009), Master's degree in Internal Medicine (Unicamp, 2011), PhD in Sciences with focus in Internal Medicine (Unicamp, 2015) and Postdoctoral in Internal Medicine (FMRP - USP-RP, 2015-2017). He is currently Assistant Professor at the Department of Pharmacology of the Institute of Biomedical Sciences of the University of São Paulo (ICB - USP) and develops research focused on the identification and characterization of antineoplastics and on the investigation of expression, activation and function of genes involved in signaling pathways cell alterations in cancer, especially hematological malignancies. (Source: Lattes Curriculum)
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Hematopoiesis is a highly organized hierarchical process responsible for the production of erythrocytes, leukocytes and platelets. In neoplastic processes, there is a change in regulatory mechanisms, leading to the replacement of healthy cells by neoplastic cells and consequent suppression of normal hematopoiesis. Despite great advances in understanding the biology of hematologic malignan…
Acute leukemias are aggressive hematological malignancies characterized by clonal proliferation with replacement and accumulation of neoplastic cells in the bone marrow, peripheral blood and other organs that suppress normal hematopoiesis. Despite the great advances in understanding the complexity involved in the molecular changes of acute leukemia in recent years, very little has been tr…
Acute leukemias comprise a group of hematological malignancies characterized by the expansion of blasts in bone marrow and peripheral blood, which is mainly due to the loss of differentiation ability of stem cells to functional cells in terminal stage, deregulation of proliferation and resistance to apoptosis. The mortality of adult patients with acute leukemia is very high, making it imp…
Acute myeloid leukemia (AML) is a heterogeneous malignant hematological neoplasm caused by the accumulation of mutations and molecular alterations in hematopoietic stem cells and corresponds to the highest number of annual deaths from leukemias. The treatment of patients with AML has remained substantially unchanged for over 30 years. Recently, the AML treatment paradigm has been overcome…
Cancer, one of the most debilitating diseases in the world, is characterized by an exacerbated and disordered proliferation of cells, which can invade adjacent tissues and spread to other organs. Cervical carcinoma is the fourth most common cancer in women and treatment options for the advanced stage are limited, leading to high mortality, while gastric cancer is the fifth most common in …
Hematopoiesis is a highly organized process responsible for the production of erythrocytes, leukocytes, and platelets, which in neoplastic processes undergo changes in regulatory processes leading to the replacement of healthy cells by neoplastic cells, observing the leukemic phenotype. Leukemias can be acute or chronic and affect myeloid and/or lymphoid progenitors and their treatment in…
(Only some records are available in English at this moment)
Acute Leukemias are aggressive neoplasms characterized by clonal proliferation with replacement and accumulation of neoplastic cells (e20%) in bone marrow and other organs and can be classified as acute myeloid leukemia (AML) or Acute Lymphoblastic Leukemia (ALL) when there is involvement of myeloblasts or lymphoblasts, respectively. Despite great advances in understanding the complexity …
Lung cancer is the most incident neoplasm in the world, with the exception of no melanoma skin cancer. In 2018 it was diagnosed in nearly 2 million people, and it was responsible for around 18,4% of the deaths among all types of cancer. Molecular mechanisms play a role in different tumor aspects, such as aggressiveness, and, although those mechanisms have already been studied, they are st…
Although widely studied, the molecular basis of breast cancer is still unclear, and the relevance of identifying new molecular markers and signaling pathways that may be useful in prognostic stratification, predicting response to therapy, and developing breast cancer new therapeutic options is evident. In this sense, the Ankyrin Repeat and KH Domain Containing 1 protein, ANKHD1, has been …
(Only some records are available in English at this moment)
Acute leukemias are aggressive neoplasms characterized by clonal proliferation with replacement and accumulation of neoplastic cells (e20%) in the bone marrow and other organs, and when there is the involvement of lymphoblasts they are classified as acute lymphoblastic leukemia (ALL). Despite great advances in understanding the complexity involved in the molecular changes of ALL, very lit…
| 1 / 1 | Ongoing research grants |
| 2 / 2 | Completed research grants |
| 6 / 6 | Ongoing scholarships in Brazil |
| 10 / 10 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 20 / 20 | All research grants and scholarships |
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CV Lattes
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