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João Agostinho Machado Neto

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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Has bachelor's degree in Biology (CEUSNP, 2009), Master's degree in Internal Medicine (Unicamp, 2011), PhD in Sciences with focus in Internal Medicine (Unicamp, 2015) and Postdoctoral in Internal Medicine (FMRP - USP-RP, 2015-2017). He is currently Assistant Professor at the Department of Pharmacology of the Institute of Biomedical Sciences of the University of São Paulo (ICB - USP) and develops research focused on the identification and characterization of antineoplastics and on the investigation of expression, activation and function of genes involved in signaling pathways cell alterations in cancer, especially hematological malignancies. (Source: Lattes Curriculum)

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Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (12)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications11
Citations20
Cit./Article1.8
Data from Web of Science

VICARI, HUGO PASSOS; LIMA, KELI; GOMES, RALPH DA COSTA; FERNANDES, DANIARA CRISTINA; LIPRERI DA SILVA, JEAN CARLOS; RODRIGUES JUNIOR, MANOEL TRINDADE; BARROSO DE OLIVEIRA, ALINE SILVA; DOS SANTOS, RICARDO NASCIMENTO; ANDRICOPULO, ADRIANO DEFINI; COELHO, FERNANDO; et al. Synthetic cyclopenta [b] indoles exhibit antineoplastic activity by targeting microtubule dynamics in acute myeloid leukemia cells. European Journal of Pharmacology, v. 894, . Web of Science Citations: 0. (19/01700-2, 13/07600-3, 19/23864-7, 15/17177-6, 17/24993-0)

HIRAKATA, CAMILA; LIMA, KELI; DE ALMEIDA, BRUNA OLIVEIRA; DE MIRANDA, LIVIA BASSANI LINS; FLORENCIO, KATHARINE GURGEL DIAS; FURTADO, LUCIANA COSTA; COSTA-LOTUFO, LETICIA VERAS; MACHADO-NETO, JOAO AGOSTINHO. Targeting glioma cells by antineoplastic activity of reversine. Oncology Letters, v. 22, n. 2, . Web of Science Citations: 0. (15/17177-6, 18/19372-9, 19/23864-7)

LIPRERI DA SILVA, JEAN CARLOS; COELHO-SILVA, JUAN LUIZ; LIMA, KELI; VICARI, HUGO PASSOS; LAZARINI, MARIANA; COSTA-LOTUFO, LETICIA VERAS; TRAINA, FABIOLA; MACHADO-NETO, JOAO AGOSTINHO. Comprehensive analysis of cytoskeleton regulatory genes identifies ezrin as a prognostic marker and molecular target in acute myeloid leukemia. CELLULAR ONCOLOGY, . Web of Science Citations: 0. (17/24993-0, 19/23864-7, 15/17177-6)

DE ALMEIDA, LARISSA COSTA; CALIL, FELIPE ANTUNES; MACHADO-NETO, JOAO AGOSTINHO; COSTA-LOTUFO, LETICIA VERAS. DNA damaging agents and DNA repair: From carcinogenesis to cancer therapy. CANCER GENETICS, v. 252, p. 6-24, . Web of Science Citations: 6. (19/23864-7)

CARLOS, JORGE ANTONIO ELIAS GODOY; LIMA, KELI; COSTA-LOTUFO, LETICIA VERAS; LEITAO, ANDREI; MACHADO-NETO, JOAO AGOSTINHO. AD80, a multikinase inhibitor, exhibits antineoplastic effects in acute leukemia cellular models targeting the PI3K/STMN1 axis. INVESTIGATIONAL NEW DRUGS, v. 39, n. 4, p. 1139-1149, . Web of Science Citations: 0. (18/15904-6, 15/17177-6, 19/23864-7, 18/19372-9, 17/24993-0)

LIMA, KELI; COELHO-SILVA, JUAN LUIZ; KINKER, GABRIELA SARTI; PEREIRA-MARTINS, DIEGO ANTONIO; TRAINA, FABIOLA; CARLOS MAGNO FERNANDES, PEDRO AUGUSTO; MARKUS, REGINA PEKELMANN; LUCENA-ARAUJO, ANTONIO ROBERTO; MACHADO-NETO, JOAO AGOSTINHO. PIP4K2A and PIP4K2C transcript levels are associated with cytogenetic risk and survival outcomes in acute myeloid leukemia. CANCER GENETICS, v. 233, p. 56-66, . Web of Science Citations: 0. (17/24993-0)

DE ALMEIDA, LARISSA COSTA; BAUERMEISTER, ANELIZE; REZENDE-TEIXEIRA, PAULA; DOS SANTOS, EVELYNE ALVES; BERALDO DE MORAES, LUIZ ALBERTO; MACHADO-NETO, JOAO AGOSTINHO; COSTA-LOTUFO, LETICIA VERAS. Pradimicin-IRD exhibits antineoplastic effects by inducing DNA damage in colon cancer cells. Biochemical Pharmacology, v. 168, p. 38-47, . Web of Science Citations: 1. (18/17595-0, 17/17648-4, 17/24993-0, 14/50926-0, 15/17177-6)

MACHADO-NETO, JOAO AGOSTINHO; CAMPOS, PAULA DE MELO; FAVARO, PATRICIA; LAZARINI, MARIANA; SANTOS DUARTE, ADRIANA DA SILVA; LORAND-METZE, IRENE; COSTA, FERNANDO FERREIRA; OLALLA SAAD, SARA TERESINHA; TRAINA, FABIOLA. Stathmin 1 inhibition amplifies ruxolitinib-induced apoptosis in JAK2(V617F) cells. ONCOTARGET, v. 6, n. 30, p. 29573-29584, . Web of Science Citations: 7. (14/23092-0, 12/09982-8, 11/51959-0, 11/06840-5)

DE ALMEIDA, BRUNA OLIVEIRA; MACHADO-NETO, JOAO AGOSTINHO. Emerging functions for ANKHD1 in cancer-related signaling pathways and cellular processes. BMB REPORTS, v. 53, n. 8, p. 413-418, . Web of Science Citations: 1. (19/23864-7, 17/24993-0, 19/25421-5)

MACHADO-NETO, JOAO AGOSTINHO; FENERICH, BRUNA ALVES; SCOPIM-RIBEIRO, RENATA; EIDE, CHRISTOPHER A.; COELHO-SILVA, JUAN LUIZ; PORTO DECHANDT, CARLOS ROBERTO; FERNANDES, JAQUELINE CRISTINA; NUNES RODRIGUES ALVES, ANA PAULA; SCHEUCHER, PRISCILA SANTOS; SIMOES, BELINDA PINTO; et al. Metformin exerts multitarget antileukemia activity in JAK2(V617F)-positive myeloproliferative neoplasms. CELL DEATH & DISEASE, v. 9, . Web of Science Citations: 2. (14/23092-0, 15/02200-2)

LIMA, KELI; COELHO-SILVA, JUAN LUIZ; KINKER, GABRIELA SARTI; PEREIRA-MARTINS, DIEGO ANTONIO; TRAINA, FABIOLA; CARLOS MAGNO FERNANDES, PEDRO AUGUSTO; MARKUS, REGINA PEKELMANN; LUCENA-ARAUJO, ANTONIO ROBERTO; MACHADO-NETO, JOAO AGOSTINHO. PIP4K2A and PIP4K2C transcript levels are associated with cytogenetic risk and survival outcomes in acute myeloid leukemia. CANCER GENETICS, v. 233, p. 56-66, . Web of Science Citations: 0. (17/24993-0)

DE ALMEIDA, LARISSA COSTA; BAUERMEISTER, ANELIZE; REZENDE-TEIXEIRA, PAULA; DOS SANTOS, EVELYNE ALVES; BERALDO DE MORAES, LUIZ ALBERTO; MACHADO-NETO, JOAO AGOSTINHO; COSTA-LOTUFO, LETICIA VERAS. Pradimicin-IRD exhibits antineoplastic effects by inducing DNA damage in colon cancer cells. Biochemical Pharmacology, v. 168, p. 38-47, . Web of Science Citations: 1. (18/17595-0, 17/17648-4, 17/24993-0, 14/50926-0, 15/17177-6)

MACHADO-NETO, JOAO AGOSTINHO; CAMPOS, PAULA DE MELO; FAVARO, PATRICIA; LAZARINI, MARIANA; SANTOS DUARTE, ADRIANA DA SILVA; LORAND-METZE, IRENE; COSTA, FERNANDO FERREIRA; OLALLA SAAD, SARA TERESINHA; TRAINA, FABIOLA. Stathmin 1 inhibition amplifies ruxolitinib-induced apoptosis in JAK2(V617F) cells. ONCOTARGET, v. 6, n. 30, p. 29573-29584, . Web of Science Citations: 7. (14/23092-0, 12/09982-8, 11/51959-0, 11/06840-5)

DE ALMEIDA, BRUNA OLIVEIRA; MACHADO-NETO, JOAO AGOSTINHO. Emerging functions for ANKHD1 in cancer-related signaling pathways and cellular processes. BMB REPORTS, v. 53, n. 8, p. 413-418, . Web of Science Citations: 1. (19/23864-7, 17/24993-0, 19/25421-5)

MACHADO-NETO, JOAO AGOSTINHO; FENERICH, BRUNA ALVES; SCOPIM-RIBEIRO, RENATA; EIDE, CHRISTOPHER A.; COELHO-SILVA, JUAN LUIZ; PORTO DECHANDT, CARLOS ROBERTO; FERNANDES, JAQUELINE CRISTINA; NUNES RODRIGUES ALVES, ANA PAULA; SCHEUCHER, PRISCILA SANTOS; SIMOES, BELINDA PINTO; et al. Metformin exerts multitarget antileukemia activity in JAK2(V617F)-positive myeloproliferative neoplasms. CELL DEATH & DISEASE, v. 9, . Web of Science Citations: 2. (14/23092-0, 15/02200-2)

MACHADO-NETO, JOAO AGOSTINHO; COELHO-SILVA, JUAN LUIZ; DE SOUZA SANTOS, FABIO PIRES; SCHEUCHER, PRISCILA SANTOS; CAMPREGHER, PAULO VIDAL; HAMERSCHLAK, NELSON; REGO, EDUARDO MAGALHAES; TRAINA, FABIOLA. Autophagy inhibition potentiates ruxolitinib-induced apoptosis in JAK2(V617F) cells. INVESTIGATIONAL NEW DRUGS, v. 38, n. 3, p. 733-745, . Web of Science Citations: 0. (14/50947-7, 14/23092-0, 17/19864-6, 13/08135-2)

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