CV Lattes
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Universidade de São Paulo (USP). Instituto de Física (IF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Prof. Leandro Barbosa has a degree (2004) and a Ph.D. (2008) in Physics from the University of São Paulo. Has experience in Physics, with emphasis on small angle X-ray scattering (SAXS), transmission electron microscopy (TEM) conventional as well as cryogenic. In recent years he has been dedicated to the study of nanoparticles with cubic structure (cubosomes) for the creation/formulation of Drug Delivery systems. It has also acted in determining the envelope of proteins without resolved structure and in determining the protein structure. It also acts in the study of the effect of denaturing agents on the structure of proteins. Since March 2011 he has been a professor in the Department of General Physics at the Physics Institute of USP, where he coordinates the Laboratory of Biosystems, belonging to the Biophysics Group at FGE. More information can be found at here (Source: Lattes Curriculum)
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One of the most interesting challenges in science is the understanding of the structure/function relationship of proteins because these macromolecules are involved in virtually all cellular physiological functions. Accordingly, this knowledge can have several applications, including the production of proteins with specific functions and defined biotechnological applications. As the loss o…
This project aims at financing the scientific visit of prof. Juan M. Ruso, from Universidad de Santiago de Compostela, Spain, to Brazil for a period of 15 days. In his visit, Prof. Ruso will actively participate in scientific discussions with me, some of my own and from others supervisors' students as well as with other researchers from our Institute. In particular we will discuss the wor…
This research project is divided into two parts; the first one will be centered in the study of the influence of ionic liquids (ILs) in biomimetic membrane systems and also in model proteins, whereas the second part (which will be developed concomitantly with the first), will be focused in the influence of drugs in the structure of liposomes (vesicles) used as carriers in different areas …
(Only some records are available in English at this moment)
Nanomedicine is an area of science with increasing interest in recent years, with special consideration for drug delivery systems. Among the several particles used for this purpose, we highlight those formed by lipids and polymers, like liposomes and cubosomes. Cubosomes are nanostructured particles formed by the addition of amphiphilic lipid (phyanthtriol) in excess of water, and their s…
One area of research that has gained much attention in recent years is nanomedicine, with particular attention to drug delivery systems. Among the various nanoparticles used for this purpose, we highlight the systems formed by lipids and polymers, such as liposomes and cubosomes. In this project we will study the structural influence of a model preotein: lysozyme in cubosomes.Lysozyme is …
Ionic Liquids (LIs) are salts composed of an organic ion and an inorganic counter ion, which is found in the liquid state at temperatures 100oC. It has both academic and industrial interest due to its potential applications in several areas, including the green chemistry. Nowadays, ILs have also been included in pharmacology, bio-medicine and bio-nanotechnology. Nevertheless, recent resul…
(Only some records are available in English at this moment)
There are several methods used to characterize small-angle X-ray scattering (SAXS) profile from biomembranes, since they are an important field of research, and this technique can provide valuable information about the membrane function, mechanical properties and also the interaction with some other system, like proteins (or peptides), some drugs aiming the construction of drug-delivery s…
| 1 / 1 | Ongoing grants |
| 5 / 5 | Completed research grants |
| 5 / 5 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 12 / 12 | All research grants and scholarships |
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