José Carlos Nicolau
CV Lattes
ResearcherID
ORCID
Secretaria da Saúde (São Paulo - Estado). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduate at Graduação em Medicina from Faculdade de Medicina de Valença (1973) and ph.d. at Clinical Medicine from Universidade Estadual de Campinas (1992). Has experience in Medicine, focusing on Medicine (Source: Lattes Curriculum)
- Diagnostic and prognostic study of SARS-CoV-2 and Influenza virus infection, AP.R
Abstract
Introduction: epidemics caused by the Influenza virus are recognized for their great impact on public health. The identification of a new coronavirus strain (SARS-CoV-2) with pandemic spread has brought new challenges for diagnosis, control and therapy. The rapid and low-cost diagnosis of SARS-CoV-2 and influenza infections may allow the adoption of measures to control transmissibility ...
- Platelet aggregation and antiaggregation in coronary artery disease patients, AP.TEM
Abstract
The recent demonstration that high on-treatment platelet reactivity is a common phenomenon, and that these patients have a worse prognosis when undergoing coronary angioplasty, along with the development of new devices for assessing platelet aggregation, reliably and relatively simple, led to an exponential increase in the scientific interest on the subject. Considering just the PubMed ...
- Effects of low-molecular-weight heparin (Enoxaparin) versus a direct thrombin inhibitor (Dabigatran) on platelet aggregation in patients with Stable Coronary Artery Disease, AP.R
Abstract
Anticoagulation with heparin is indicated in several situations, such as acute coronary disease (in combination with antiplatelet therapy) for the prevention and treatment of venous thromboembolism and situations with high risk of thromboembolism, such as atrial fibrillation, hemodialysis and invasive procedures such as radiofrequency ablation, among others. However some studies about ...
- Mechanisms involved in increased risk of bleeding in patients with prior stroke or transient ischemic attack in use of aspirin, AP.R
Abstract
Study population: 100 patients with prior Ischemic Stroke or Transient Ischemic Attack, previous hospitalization due to Acute Coronary Syndrome (unstable angina, non-ST elevation or ST-elevation myocardial infarction), current use of ASA. Exclusion Criteria: Previously known hemorrhagic stroke; use of another antiplatelet agent than ASA; use of NSAIDs and / or dipyridamole; known plat...
- Possible drug interaction between clopidogrel and ranitidin or omeprazol in patients with stable coronary artery disease: a comparative study, AP.R
Abstract
Study population: 100 pacientes com Doença Arterial Coronária crônica selecionados do ambulatório da UCCA 100 patients with Stable Coronary Artery Disease from the Heart Institute Inclusion Criteria: Age > 18 years old; coronary artery disease, defined as previous myocardial infarction and/or coronary angioplasty and/or CABG surgery and/or coronariography showing obstruction of at leas...
(Only some records are available in English at this moment)
- The importance of platelet aggregability in different presentations of Coronary Artery Disease: from subclinical Atherosclerosis to Acute Coronary Syndromes, BP.PD
Abstract
There is evidence that platelets participate from the beginning of the atherosclerotic process (pre-clinical stage) to late stage of Coronary Disease, in which rupture or erosion of atherosclerotic plaque occurs, with consequent development of some form of Acute Coronary Syndromes(ACS): a) platelets may be involved in Atherosclerosis and formation of the foam cell, even in the absence o...
- Standardization of adenosine erythrocyte reuptake technique in patients on dual antiplatelet therapy in INCOR-HC laboratory INCOR-HC, BP.IC
Abstract
It is known that in comparison to clopidogrel, ticagrelor shows significant benefit regarding ischemic events and mortality. The importance of these findings, to some extent unexpected, raised the hypothesis that other properties of the medication could be partially responsible for these benefits. Recently, ticagrelor has been shown to be associated with increased adenosine plasma level...
- Comparison of platelet aggregation by VerifyNow Aspirin® and Multiplate ASPI® methods in coronary disease patients with Diabetes Mellitus, BP.IC
Abstract
The association between diabetes and platelet reactivity is well known and a recent publication has shown that the recurrence of thrombotic events in the month following acute coronary syndrome treated with percutaneous coronary intervention is four times higher in the diabetic than in the non-diabetic population. The effect of oral hypoglycemic treatment on the acute phase of myocardia...
- Comparing intraoral bleeding time with platelet aggregability by the Multiplate ADP method in coronary artery disease patients undergoing tooth extraction, BP.IC
Abstract
The tooth loss and the need for extractions are still a reality in the Brazilian population. There is great concern among dentists regarding the use of antiplatelet agents, in relation to the increased risk of bleeding in patients undergoing oral surgery. It is very important the development of dental surgical care insurance protocols to patients on dual antiplatelet therapy. In this co...
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing research grants |
| 8 / 5 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 8 / 6 | Completed scholarships in Brazil |
| 19 / 14 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 2 |
| Citations | 8 |
| Cit./Article | 4.0 |
| Data from Web of Science | |
GUTIERREZ, JAIME A.; GOMEZ, ISABEL; CHIARELLO, I, DELIA; SALSOSO, ROCIO; KLEIN, ANDRES D.; GUZMAN-GUTIERREZ, ENRIQUE; TOLEDO, FERNANDO; SOBREVIA, LUIS. Role of proteases in dysfunctional placental vascular remodelling in preeclampsia. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, v. 1866, n. 2, FEB 1 2020. Web of Science Citations: 1. (17/26922-2)
DE MENDONCA FURTADO, REMO HOLANDA; GIUGLIANO, ROBERT PATRICK; CASSARO STRUNZ, CELIA MARIA; CAVALHEIRO FILHO, CYRILLO; FRANCHINI RAMIRES, JOSE ANTONIO; KALIL FILHO, ROBERTO; LEMOS NETO, PEDRO ALVES; PEREIRA, ALEXANDRE COSTA; ROCHA, TANIA RUBIA; FREIRE, BEATRIZ TONON; et al. Drug Interaction Between Clopidogrel and Ranitidine or Omeprazole in Stable Coronary Artery Disease: A Double-Blind, Double Dummy, Randomized Study. American Journal of Cardiovascular Drugs, v. 16, n. 4, p. 275-284, AUG 2016. Web of Science Citations: 7. (10/16324-1)