José Carlos Nicolau

• Abstract

  Epidemics caused by the Influenza virus are recognized for their great impact on public health. The identification of a new coronavirus strain (SARS-CoV-2) with pandemic spread has brought new challenges for diagnosis, control and therapy. The rapid and low-cost diagnosis of SARS-CoV-2 and influenza infections may allow the adoption of measures to control transmissibility both in the envi…

  Diagnostic and prognostic study of SARS-CoV-2 and Influenza virus infection, AP.R

• Abstract

  The recent demonstration that high on-treatment platelet reactivity is a common phenomenon, and that these patients have a worse prognosis when undergoing coronary angioplasty, along with the development of new devices for assessing platelet aggregation, reliably and relatively simple, led to an exponential increase in the scientific interest on the subject. Considering just the PubMed da…

  Platelet aggregation and antiaggregation in coronary artery disease patients, AP.TEM

• Abstract

  Anticoagulation with heparin is indicated in several situations, such as acute coronary disease (in combination with antiplatelet therapy) for the prevention and treatment of venous thromboembolism and situations with high risk of thromboembolism, such as atrial fibrillation, hemodialysis and invasive procedures such as radiofrequency ablation, among others. However some studies about in…

  Effects of low-molecular-weight heparin (Enoxaparin) versus a direct thrombin inhibitor (Dabigatran) on platelet aggregation in patients with Stable Coronary Artery Disease, AP.R

(Only some records are available in English at this moment)

• Abstract

  There is evidence that platelets participate from the beginning of the atherosclerotic process (pre-clinical stage) to late stage of Coronary Disease, in which rupture or erosion of atherosclerotic plaque occurs, with consequent development of some form of Acute Coronary Syndromes(ACS): a) platelets may be involved in Atherosclerosis and formation of the foam cell, even in the absence of …

  The importance of platelet aggregability in different presentations of Coronary Artery Disease: from subclinical Atherosclerosis to Acute Coronary Syndromes, BP.PD

• Abstract

  It is known that in comparison to clopidogrel, ticagrelor shows significant benefit regarding ischemic events and mortality. The importance of these findings, to some extent unexpected, raised the hypothesis that other properties of the medication could be partially responsible for these benefits. Recently, ticagrelor has been shown to be associated with increased adenosine plasma levels …

  Standardization of adenosine erythrocyte reuptake technique in patients on dual antiplatelet therapy in INCOR-HC laboratory INCOR-HC, BP.IC

• Abstract

  The association between diabetes and platelet reactivity is well known and a recent publication has shown that the recurrence of thrombotic events in the month following acute coronary syndrome treated with percutaneous coronary intervention is four times higher in the diabetic than in the non-diabetic population. The effect of oral hypoglycemic treatment on the acute phase of myocardial …

  Comparison of platelet aggregation by VerifyNow Aspirin® and Multiplate ASPI® methods in coronary disease patients with Diabetes Mellitus, BP.IC

(Only some records are available in English at this moment)