A Saint Louis encephalitis and Rocio virus serosurvey in Brazilian horses

Author(s):Show less -

Silva, Jaqueline Raymondi ^[1] ; Romeiro, Marilia Farignoli ^[1] ; de Souza, William Marciel ^[1] ; Munhoz, Thiago Demarchi ^[2] ; Borges, Gustavo Puia ^[3] ; Brioschi Soares, Otavio Augusto ^[4] ; Coelho de Campos, Carlos Henrique ^[4] ; Machado, Rosangela Zacarias ^[2] ; Cristiny Rodrigues Silva, Maria Luana ^[5] ; Maia Faria, Joice Lara ^[6] ; Chavez, Juliana Helena ^[1] ; Moraes Figueiredo, Luiz Tadeu ^[1]

Affiliation

^[1] Univ Sao Paulo, Fac Med Ribeirao Preto, Ctr Pesquisa Virol, BR-14049 Ribeirao Preto, SP - Brazil

^[2] Univ Estadual Paulista, Fac Ciencias Agr & Vet, Jaboticabal, SP - Brazil

^[3] Univ Fed Mato Grosso do Sul, Escola Ciencias Vet, Campo Grande, MS - Brazil

^[4] Acad Militar Agulhas Negras, Rio De Janeiro, RJ - Brazil

^[5] Univ Fed Campina Grande, Unidade Acad Med Vet, Campina Grande, PB - Brazil

^[6] Univ Uberaba, Fac Med Vet, Uberaba, MG - Brazil

• Document type: Journal article
• Source: Revista da Sociedade Brasileira de Medicina Tropical; v. 47, n. 4, p. 414-417, JUL-AUG 2014.
• Web of Science Citations: 10

Abstract

Introduction: Arboviruses are an important public health problem in Brazil, in especially flaviviruses, including the Saint Louis encephalitis virus (SLEV) and the Rocio virus (ROCV), are especially problematic. These viruses are transmitted to humans or other vertebrates through arthropod bites and may cause diseases with clinical manifestations that range from asymptomatic infection, viral hemorrhagic fever to encephalitis. Methods: A serological survey of horses from various regions of Brazil using an enzyme-linked immunosorbent assay (ELISA) with recombinant SLEV domain III peptides and ROCV E protein as antigens. Results: Overall, 415 (55.1%) of the 753 horses that were screened were seropositive for flavivirus and, among them, monotypic reactions were observed to SLEV in 93 (12.3%) and to ROCV in 46 (6.1%). These results suggested that these viruses, or other closely related viruses, are infecting horses in Brazil. However, none of the studied horses presented central nervous system infection symptoms. Conclusions: Our results suggest that SLEV and ROCV previously circulated among horses in northeast, west-central and southeast Brazil. (AU)

• FAPESP's process: 08/50617-6 - Studies on emerging viruses including arbovirus, robovirus, respiratory viruses and congenital transmission, at the Centro de Pesquisa em Virologia da Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo
• Grantee: Luiz Tadeu Moraes Figueiredo
• Support type: Research Projects - Thematic Grants
• FAPESP's process: 12/24150-9 - Research of virus in wild rodents, mosquitoes and ticks
• Grantee: William Marciel de Souza
• Support type: Scholarships in Brazil - Doctorate
• FAPESP's process: 12/02836-6 - Development of Real Time RT-PCR Techniques for arbovirus that cause human disease and nucleotide sequencing identification of them
• Grantee: Marilia Farignoli Romeiro
• Support type: Scholarships in Brazil - Master