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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Sialidase Production and Genetic Diversity in Clostridium perfringens Type A Isolated from Chicken with Necrotic Enteritis in Brazil

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Author(s):
Llanco, Luis A. [1] ; Nakano, Viviane [1] ; Avila-Campos, Mario J. [1]
Total Authors: 3
Affiliation:
[1] Univ Sao Paulo, Inst Biomed Sci, Dept Microbiol, Anaerobe Lab, Sao Paulo - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Current Microbiology; v. 70, n. 3, p. 330-337, MAR 2015.
Web of Science Citations: 6
Abstract

The sialidase activity and genetic diversity of 22 Clostridium perfringens strains isolated from chickens with necrotic enteritis were determined. Sialidase activity was detected in 86.4 % of the strains. All C. perfringens showed a high value of similarity (>96 %), and they were grouped into seven clusters clearly separated from the other reference bacterial strains. From these clusters four patterns were defined in accordance with their phenotypic (sialidase production and antibiotic resistance profile) and genotypic (presence of nanI and nanJ genes) characteristics. Our results showed heterogeneity among strains, but they were genotypically similar, and it is suggested further studies are needed to better understand the pathogenesis of necrotic enteritis. (AU)

FAPESP's process: 09/03792-0 - Expression of Bacteroides fragilis bmeBAC efflux pump genes in Escherichia coli and characterization of the substrate profiles of the BmeABC pumps
Grantee:Viviane Nakano
Support Opportunities: Scholarships in Brazil - Young Researchers
FAPESP's process: 13/17739-9 - Clonal evaluation of Clostridium perfringens strains isolated from humans and animals by Multilocus sequence typing (MLST)
Grantee:Mario Júlio Ávila-Campos
Support Opportunities: Regular Research Grants