Tandem mass spectrometry (ICP-MS/MS) for overcoming molybdenum oxide interferences on Cd determination in milk

Author(s)

Amais, Renata S. ^[1] ; Virgilio, Alex ^[2] ; Schiavo, Daniela ^[3] ; Nobrega, Joaquim A. ^[2]

Affiliation

^[1] Univ Sao Paulo, Ctr Nucl Energy Agr, BR-13416000 Piracicaba, SP - Brazil

^[2] Univ Fed Sao Carlos, Dept Chem, Grp Appl Instrumental Anal, BR-13565905 Sao Carlos, SP - Brazil

^[3] Agilent Technol Brazil, BR-06460040 Barueri, SP - Brazil

• Document type: Journal article
• Source: Microchemical Journal; v. 120, p. 64-68, MAY 2015.
• Web of Science Citations: 28

Abstract

It is well known that molybdenum oxides affect Cd determination by inductively coupled plasma mass spectrometry (ICP-MS). It is proposed here a procedure for simultaneous determination of Cd and Mo. The effectiveness of the ICP-MS with tandem configuration (ICP-MS/MS) using octopole reaction system (ORS3) pressurized with oxygen gas and MS/MS mode to overcome Mo oxide-based interferences on Cd determination was evaluated. Cadmium was determined as free atom ion and Mo was determined as MoO2+ employing a 0.5 mL min(-1) oxygen gas flow rate into the ORS3. Non-fat and whole milk powder certified reference materials (NIST SRM 8435 and SRM 1549) were used for checking the accuracy of the proposed procedure. The microwave-assisted digestion was carried out using diluted nitric acid solution (2.6 mol L-1 HNO3) and hydrogen peroxide (30% m m(-1)). According to Student's t-test, reference and determined values were in agreement at a 95% confidence level, except for Cd-111 and Cd-113 in SRM 1549. (C) 2015 Elsevier B.V. All rights reserved. (AU)

• FAPESP's process: 13/26857-5 - Total concentrations and chemical speciation of As, Cr and Se using low pressure monolithic columns and inductively coupled plasma techniques
• Grantee: Renata Stábile Amais
• Support type: Scholarships in Brazil - Post-Doctorate