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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Extraction of phenolic compounds from pepper-rosmarin (Lippia sidoides Cham.) leaves by sequential extraction in fixed bed extractor using supercritical CO2, ethanol and water as solvents

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Garmus, Tabata T. [1] ; Paviani, Losiane C. [1] ; Queiroga, Carmen L. [2] ; Cabral, Fernando A. [1]
Total Authors: 4
[1] Univ Estadual Campinas, Dept Food Engn, BR-13083862 Campinas, SP - Brazil
[2] Univ Estadual Campinas, Chem Biol & Agr Pluridisciplinaiy Res Ctr CPQBA, BR-13083970 Campinas, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: JOURNAL OF SUPERCRITICAL FLUIDS; v. 99, p. 68-75, APR 2015.
Web of Science Citations: 20

Extraction of bioactive compounds requires frequent changes in the extraction techniques due to the quality requirements in the food, pharmaceutical and cosmetic industries. The compounds of the polyphenolic family represent an important group of bioactive compounds in food, and are present in various types of plants, including Lippia sidoides Cham., also known as pepper-rosmarin, an aromatic plant with therapeutic properties. Thus, this study aimed to investigate the sequential extraction (in fixed bed and high pressure) of bioactive compounds from L. sidoides leaves, using supercritical carbon dioxide, ethanol, and water as solvents and, compare the global yield, total phenolics, total flavonoids, and antioxidant activity of extracts obtained from sequential extraction with the extracts obtained by one-step extraction in fixed bed (high pressure) and by conventional extraction. The results showed that the combination of extraction processes is an effective method to obtain extracts with different compositions and functionalities. Overall, the ethanolic extraction in fixed bed and the three-step sequential extraction showed the best results in terms of global yield, and content and yield of total phenolics and flavonoids. The ethanol extracts exhibited the best antioxidant activity, which may be related to the presence of phenolic compounds. (C) 2015 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 11/14309-8 - Extracts from Eugenia uniflora L. and Lippia sidoides Cham. leaves by sequential extraction in fixed bed using supercritical CO2, ethanol and water as solvents
Grantee:Tábata Tayara Garmus
Support Opportunities: Scholarships in Brazil - Master