Effect of Er,Cr:YSGG laser application in the treatment of experimental periodontitis

Author(s)

Pavone, Chaine ^[1] ; Perussi, Livia Rodrigues ^[1] ; Pimentel Lopes de Oliveira, Guilherme Jose ^[1] ; Scardueli, Cassio Rocha ^[1] ; Cirelli, Joni Augusto ^[1] ; Cerri, Paulo Sergio ^[1] ; Marcantonio Junior, Elcio ^[1] ; Spolidorio, Luis Carlos ^[1] ; Chierici Marcantonio, Rosemary Adriana ^{[1, 2]}

Affiliation

^[1] Sao Paulo State Univ Julio de Mesquita Filho, Araraquara Dent School, BR-14801903 Sao Paulo - Brazil

^[2] Sao Paulo State Univ Julio de Mesquita Filho, Diagnost & Surg Dept Periodontol, Araraquara Dent Sch, BR-14801903 Sao Paulo - Brazil

• Document type: Journal article
• Source: Lasers in Medical Science; v. 30, n. 3, p. 993-999, APR 2015.
• Web of Science Citations: 11

Abstract

The purpose of this study was to evaluate the influence of an erbium, chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser in the absence or presence of manual scaling and root planning (SRP) for the treatment of induced periodontitis in rats. Ligatures were placed in the subgingival region of the maxillary first molar. After a 7-day period, the ligatures were removed, and 40 rats were randomly divided into four groups (G), as follows: (GI) no treatment, (GII) scaling and root planning (SRP) with curettes, (GIII) Er,Cr:YSGG laser irradiation and (GIV) SRP with curettes followed by Er,Cr:YSGG laser irradiation. Seven and 30 days after the treatment, the animals were sacrificed and histologic, histometric and immunohistochemistry analyses were performed. All groups showed similar histopathological characteristics during the evaluation period. The histometric analysis was confirmed using Bonferroni and paired t tests. At 7 and 30 days, groups II, III and IV exhibited greater bone formation in the furcation area when compared to group I (p < 0.0001; p < 0.05). During the 7-day period, the groups irradiated with the laser (III and IV) showed a statistically larger new bone area than the group treated with SRP (II) (p < 0.01). Immunohistochemistry analysis revealed that the control group exhibited a higher expression of tartrate-resistant acid phosphatase (TRAP) and the receptor activator of nuclear factor kappa I' ligand (RANKL) when compared to groups II, III and IV (p < 0.05). All treatments were able to reduce the inflammatory processes, consequently enabling the repair of periodontal tissues. The results achieved with the application of the Er,Cr:YSGG laser suggest that this laser can stimulate greater bone formation, especially over a shorter period of time. (AU)

• FAPESP's process: 09/00479-9 - Utilization of laser Er-Cr: YSGG in soft and hard tissue repair and in the treatment of induced periodontal disease: analyses histological and immune-inflammatory in rats
• Grantee: Rosemary Adriana Chierici Marcantonio
• Support Opportunities: Regular Research Grants