Electrochemical sensor for nitric oxide using layered films composed of a polycationic dendrimer and nickel(II) phthalocyaninetetrasulfonate deposited on a carbon fiber electrode

Author(s)

Cancino, Juliana ^{[1, 2, 3, 4]} ; Borgmann, Sabine ^{[2, 3, 5]} ; Machado, Sergio A. S. ^[1] ; Zucolotto, Valtencir ^[4] ; Schuhmann, Wolfgang ^{[2, 3, 5]} ; Masa, Justus ^{[2, 3]}

Affiliation

^[1] Univ Sao Paulo, Grp Mat Eletroquim & Metodos Eletroanalit, Inst Quim Sao Carlos, BR-13566590 Sao Carlos, SP - Brazil

^[2] Ruhr Univ Bochum, Analyt Chem Elektroanalyt & Sensor, D-44780 Bochum - Germany

^[3] Ruhr Univ Bochum, Ctr Electrochem Sci CES, D-44780 Bochum - Germany

^[4] Univ Sao Paulo, Nanomed & Nanotoxicol Grp, Inst Fis Sao Carlos, BR-13560970 Sao Carlos, SP - Brazil

^[5] Ruhr Univ Bochum, Res Dept Interfacial Syst Chem, D-44780 Bochum - Germany

• Document type: Journal article
• Source: Microchimica Acta; v. 182, n. 5-6, p. 1079-1087, APR 2015.
• Web of Science Citations: 5

Abstract

We have developed an electrochemical sensor for nitric oxide that is based on multi-layers of nickel(II) phthalocyaninetetrasulfonate and a polyamidoamine dendrimer assembled on the surface of a carbon-fiber microelectrode. This sensor responds to nitric oxide at a working potential of 800 mV with a sensitivity of 5.54 pAa (TM)mu MaEuro3/4(1) which, however, depends on the dendrimer layer position deposited on the microelectrode. The limit of detection is as low as 5.5 mu M at a signal-to-noise ratio of 3. The electrode exhibits good selectivity for nitric oxide over common interferents including dopamine, nitrite, hydrogen peroxide, norepinephrine, epinephrine and ascorbic acid. (AU)

• FAPESP's process: 08/00546-5 - Self-organization in the development of sensors, biosensors and membrane models for application in nanomedicine
• Grantee: Juliana Cancino Bernardi
• Support type: Scholarships in Brazil - Doctorate