| Full text | |
| Author(s): |
Linan, Lamia Zuniga
[1]
;
Nascimento Lima, Nadson M.
[1]
;
Maciel Filho, Rubens
[1]
;
Sabino, Marcos A.
[2]
;
Kozlowski, Mark T.
[3]
;
Manenti, Flavio
[4]
Total Authors: 6
|
| Affiliation: | [1] Univ Estadual Campinas, UNICAMP, Sch Chem Engn, BR-13083852 Campinas, SP - Brazil
[2] Univ Simon Bolivar, Dept Quim, Grp B5IDA, Caracas 1080A - Venezuela
[3] CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 - USA
[4] Politecn Milan, Dipartamento Chim Mat & Ingn Chim, I-20133 Milan - Italy
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | Materials Science & Engineering C-Materials for Biological Applications; v. 51, p. 107-116, JUN 1 2015. |
| Web of Science Citations: | 3 |
| Abstract | |
This work presents the rheological assessment of poly(methyl methacrylate) (PMMA) polymers synthesized in a dedicated pilot-scale plant. This material is to be used for the construction of scaffolds via Rapid Prototyping (RP). The polymers were prepared to match the physical and biological properties required for medical applications. Differential Scanning Calorimetry (DSC) and Size Exclusion Chromatography (SEC) measurements verified that the synthesized polymers were atactic, amorphous and linear in chains. Rheological properties such as viscosity, storage and loss modulus, beyond the loss factor, and creep and recovery were measured in a plate-plate sensor within the viscoelastic linear region. The results showed the relevant influence of the molecular weight on the viscosity and elasticity of the material, and how, as the molecular weight increases, the viscoelastic properties are getting closer to those of human bone. This article demonstrates that by using the implemented methodology it is possible to synthesize a polymer, with properties comparable to commercially-available PMMA. (C) 2015 Elsevier B.V. All rights reserved. (AU) | |
| FAPESP's process: | 11/09631-8 - Study and modeling of poly(methyl methacrylate) production process to obtain artificial bone tissue |
| Grantee: | Rubens Maciel Filho |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 10/16952-2 - MODELING AND OPTIMAL CONTROL BY FUZZY LOGIC FOR PROCESSES OF PRODUCTION OF BIOMATERIALS |
| Grantee: | Nádson Murilo Nascimento Lima |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 09/09092-0 - Study and modeling of the process of production of PMMA for the fabrication of artificial bone cement |
| Grantee: | Lamia Zuniga Linan |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |