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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Sleep disorders in patients with myasthenia gravis: a systematic review

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Oliveira, Ezequiel Fernandes [1] ; Nacif, Sergio R. [1] ; Pereira, Nixon Alves [1] ; Fonseca, Nina Teixeira [1] ; Urbano, Jessica Julioti [1] ; Perez, Eduardo Araujo [1] ; Cavalcante, Valeria [2] ; Oliveira, Claudia Santos [1] ; Insalaco, Giuseppe [3] ; Oliveira, Acary Sousa Bulle [2] ; Franco Oliveira, Luis Vicente [1]
Total Authors: 11
[1] Nove de Julho Univ, UNINOVE, Sleep Lab, Rehabil Sci Masters & PhD Degree Program, Sao Paulo, SP - Brazil
[2] Fed Univ Sao Paulo UNIFESP, Dept Neurol & Neurosurg, Div Neuromuscular Disorders, Sao Paulo - Brazil
[3] Natl Res Council Italy, Inst Biomed & Mol Immunol A Monroy, Rome - Italy
Total Affiliations: 3
Document type: Review article
Source: Journal of Physical Therapy Science; v. 27, n. 6, p. 2013-2018, JUN 2015.
Web of Science Citations: 6

{[}Purpose] This systematic review evaluated the presence of sleep-disordered breathing in patients with myasthenia gravis and clarified the role of physiotherapy. {[}Subjects and Methods] We followed the PRISMA declaration criteria. The evaluation was performed in accordance with the STROBE statement for observational and cross-sectional studies and the CONSORT checklist for clinical trials. Searches were followed by hand on MEDLINE, EMBASE, SciELO, PubMed Central, and the Cochrane Central Register of Controlled Trials. {[}Results] Our searches yielded a total of 36 studies published between 1970 and 2014. The number of patients involved ranged from 9-490. Of the 36 studies, 19 articles were excluded because they did not meet the inclusion criteria. Therefore, 17 observational, cross-sectional, or clinical studies assessing the quality of sleep and prevalence of sleep disorders in patients with myasthenia gravis were eligible for our review. {[}Conclusion] Some studies of patients with MG show that patients with MG are associated with poor sleep quality, excessive daytime sleepiness, presence of restless syndrome, and a higher incidence of SDB, while other studies do not report such associations. Therefore, given the current inconclusive evidence and limited literature, further study of sleep disturbances in patients with MG is needed. (AU)

FAPESP's process: 13/21765-5 - Resistance and compliance of lungs in decellularization and recellularization process with stem cell.
Grantee:Nadua Apostólico
Support type: Scholarships in Brazil - Master
FAPESP's process: 14/07262-3 - Effect of hemodialysis on upper airways collapsibility in patients with chronic kidney disease
Grantee:Nina Teixeira Fonsêca
Support type: Scholarships in Brazil - Master