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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Bone mineral density in short bowel syndrome: correlation with BMI and serum vitamins C, E and K

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Author(s):
Moreno Braga, Camila Bitu [1] ; Bizari, Leticia [1] ; Marques Suen, Vivian Miguel [1] ; Marchini, Julio Sergio [1] ; Albuquerque de Paula, Francisco Jose [2] ; de Carvalho da Cunha, Selma Freire [1]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo FMRP USP, Ribeirao Preto Med Sch, Dept Internal Med, Div Med Nutr, Ribeirao Preto, SP - Brazil
[2] FMRP USP, Dept Internal Med, Div Endocrinol, Ribeirao Preto, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Arquivos Brasileiros de Endocrinologia e Metabologia; v. 59, n. 3, p. 252-258, JUN 2015.
Web of Science Citations: 3
Abstract

Objective: Bone loss has been established as a major extra-intestinal complication of short bowel syndrome (SBS). The purpose of this study was to correlate bone mineral density (BMD) with body mass index (BMI), serum vitamin and mineral levels in patients with SBS. Material and methods: The study was conducted on 13 patients (8 male and 5 female, 54.7 +/- 11.4 years) with SBS (residual small bowel length of 10 to 100 cm). We determined the food ingestion, anthropometry, serum levels of vitamins C, A, D, E and K, as well as serum and urinary levels of phosphorus and calcium. BMD was measured by dual-energy x-ray absorptiometry (DXA). Results: Osteopenia and osteoporosis was diagnosed in all but one SBS patient. Serum levels of vitamin D were low in all volunteers. Sixty-one percent of patients had vitamin E deficiency; hypovitaminosis A and C occurred in one subject. BMI and C, E and K vitamin serum levels correlated with T-score of BMD. Conclusions: Osteopenia and osteoporosis were common in SBS patients. There was a correlation between BMD and the serum levels of vitamins C, E and K, an indicative that such vitamins may influence bone health. (AU)