Silsesquioxane organofunctionalized with 4-amino-3-hydrazino-5-mercapto-1,2,4-triazole: Preparation and subsequent reaction with silver and potassium hexacyanoferrate(III) for detection of L-cysteine

Author(s)

do Carmo, Devaney R. ^[1] ; Silvestrini, Daniela R. ^[1] ; da Silveira, Tayla F. S. ^[1] ; Cumba, Loanda R. ^[1] ; Dias Filho, Newton L. ^[1] ; Soares, Layciane A. ^[1]

Affiliation

^[1] Univ Estadual Paulista Julio Mesquita Filho UNESP, Dept Quim & Fis, BR-15385000 Ilha Solteira, SP - Brazil

• Document type: Journal article
• Source: Materials Science & Engineering C-Materials for Biological Applications; v. 57, p. 24-30, DEC 1 2015.
• Web of Science Citations: 6

Abstract

The octalds(3-chloropropyl)octasilsesquioxane (SS) was organofunctionalized with 4-amino-3-hydrazino-5mercapto-1,2,4-triazole (Purpald). The functionalized silsesquioxane with Purpald (SP) was characterized by Fourier transform infrared spectroscopy (FT-IR), and nuclear magnetic resonance (NMR). After functionalized, silsesquioxane can interact with silver nitrate and subsequently with potassium hexacyanoferrate (III) (AgHSP). The novel hybrid composite formed (AgHSP) was characterized by Fourier transform infrared spectra, scanning electron microscopy (SEM), and energy dispersive X-ray spectroscopy (EDX). AgHSP was electrochemically characterized by cyclic voltammetry (CV) using graphite paste electrode. The AgHSP incorporated into a graphite paste electrode (20% w/w) was tested for detection of L-cysteine. The modified electrode showed a linear response from 9.0 x 10(-5) to 5.0 x 10(-3) mol L-1 with the corresponding equation Y(A) = 0.01315 + 1.865 {[}L-cysteine], and a correlation coefficient of r(2) = 0.9995. The method showed a detection limit of 1.76 x 10(-4) mol L-1 with a relative standard deviation of +/- 2% (n = 3) and amperometric sensitivity of 1.865 A/mol L-1. (C) 2015 Elsevier B.V. All rights reserved. (AU)

• FAPESP's process: 12/11306-0 - Electrochemical quantification of analytes of environmental and biological interest, using new materials prepared from functionalized silsesquioxanes.
• Grantee: Daniela Silvestrini Fernandes
• Support type: Scholarships in Brazil - Doctorate
• FAPESP's process: 13/08495-9 - Porous materials and composites chemically modified with zirconium (IV) and phosphoric acid: Preparation and electroanalytical applications.
• Grantee: Tayla Fernanda Serantoni da Silveira
• Support type: Scholarships in Brazil - Doctorate
• FAPESP's process: 12/05438-1 - Development of novel nanostructured organically functionalized hybrid silsesquioxanes: preparation, characterization and its application as a sensor of compounds and ions of environmental and biological interest
• Grantee: Devaney Ribeiro Do Carmo
• Support type: Regular Research Grants