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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Electrochemical investigation of the voltammetric determination of hydrochlorothiazide using a nickel hydroxide modified nickel electrode

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Author(s):
Machini, Wesley B. S. [1] ; David-Parra, Diego N. [1] ; Teixeira, Marcos F. S. [1]
Total Authors: 3
Affiliation:
[1] Sao Paulo State Univ UNESP, Fac Sci & Technol, BR-19060900 Presidente Prudente, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Materials Science & Engineering C-Materials for Biological Applications; v. 57, p. 344-348, DEC 1 2015.
Web of Science Citations: 9
Abstract

The preparation and electrochemical characterization of a nickel hydroxide modified nickel electrode as well as its behavior as electrocatalyst toward the oxidation of hydrochlorothiazide (HCTZ) were investigated. The electrochemical behavior of the modified electrode and the electrooxidation of HCTZ were explored using cyclic voltammetry. The voltammetric response of the modified electrode in the detection of HCTZ is based on the electrochemical oxidation of the Ni(II)/Ni(III) and a chemical redox process. The analytical parameters for the electrooxidation of HCTZ by the nickel hydroxide modified nickel electrode were obtained in NaOH solution, in which the linear voltammetric response was in the concentration range from 1.39 x 10(-5) to 1.67 x 10(-4) Mol L-1 with a limit of detection of 7.92 x 10(-6) Mol L-1 and a sensitivity of 0.138 mu A L mmol(-1). Tafel analysis was used to elucidate the kinetics and mechanism of HCTZ oxidation by the modified electrode. (C) 2015 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 13/10469-6 - Electroanalytical application of the biomimetic manganese(IV) complex containing 2,3,5,6-tetrakis(2-pyridyl)pyrazine ligant
Grantee:Wesley Bruno da Silva Machini
Support Opportunities: Scholarships in Brazil - Master