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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Associations between single nucleotide polymorphisms and carcass traits in Nellore cattle using high-density panels

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Author(s):
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Espigolan, R. [1] ; Baldi, F. [1] ; Boligon, A. A. [1, 2] ; Souza, F. R. P. [1, 3] ; Fernandes Junior, G. A. [1] ; Gordo, D. G. M. [1] ; Venturini, G. C. [1] ; de Camargo, G. M. F. [1] ; Feitosa, F. L. B. [1] ; Garcia, D. A. [1] ; Tonhati, H. [1] ; Chardulo, L. A. L. [4] ; Oliveira, H. N. [1] ; Albuquerque, L. G. [1]
Total Authors: 14
Affiliation:
[1] Fac Ciecias Agr & Vet, Dept Zootecnia, Jaboticabal, SP - Brazil
[2] Univ Fed Pelotas, Dept Zootecnia, Pelotas, RS - Brazil
[3] Univ Fed Pelotas, Dept Ecol Zool & Genet, Inst Biol, Pelotas, RS - Brazil
[4] Univ Estadual Paulista, Fac Med Vet & Zootecnia, Depat Melhoramento & Nutricao Anim, Botucatu, SP - Brazil
Total Affiliations: 4
Document type: Journal article
Source: Genetics and Molecular Research; v. 14, n. 3, p. 11133-11144, 2015.
Web of Science Citations: 4
Abstract

The objective of this study was to evaluate associations between single nucleotide polymorphism (SNP) markers and carcass traits measured postmortem in Nellore cattle. Records of loin eye area (LEA) and backfat thickness (BF) from 740 males and records of hot carcass weight (HCW) from 726 males were analyzed. All of the animals were genotyped using the BovineHD BeadChip. Association analyses were performed by the restricted maximum likelihood method that considered one SNP at a time. Significant SNPs were identified on chromosomes 2 and 6 for LEA and on chromosomes 7, 1, and 2 for BF. For HCW, associations with SNPs were found on chromosomes 13, 14, and 28, in addition to genome regions that were directly related to this trait, such as the EFCAB8 and VSTM2L genes, and to bone development (RHOU). Some SNPs were located in very close proximity to genes involved in basal metabolism (BLCAP, NNAT, CTNNBL1, TGM2, and LOC100296770) and the immune system (BPI). (AU)

FAPESP's process: 09/16118-5 - Genomic tools to genetic improvement of direct economic important traits in Nelore cattle
Grantee:Lucia Galvão de Albuquerque
Support type: Research Projects - Thematic Grants
FAPESP's process: 10/14580-0 - Association study among single nucleotide polymorphisms with carcass and meat traits in Nellore cattle using high density painels
Grantee:Rafael Espigolan
Support type: Scholarships in Brazil - Master