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Genomic tools to genetic improvement of direct economic important traits in Nelore cattle

Grant number: 09/16118-5
Support Opportunities:Research Projects - Thematic Grants
Duration: February 01, 2011 - January 31, 2017
Field of knowledge:Agronomical Sciences - Animal Husbandry - Genetics and Improvement of Domestic Animals
Principal Investigator:Lucia Galvão de Albuquerque
Grantee:Lucia Galvão de Albuquerque
Host Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil
Pesquisadores principais:
Maria Eugênia Zerlotti Mercadante
Associated researchers: Fabio Ricardo Pablos de Souza ; Fernando Flores Cardoso ; Fernando Sebastián Baldi Rey ; Flávio Schramm Schenkel ; Guilherme Jordão de Magalhães Rosa ; Henrique Nunes de Oliveira ; Humberto Tonhati ; Jesus Aparecido Ferro ; José Fernando Garcia ; Joslaine Noely dos Santos Goncalves Cyrillo ; Luis Artur Loyola Chardulo ; Maria Eugênia Zerlotti Mercadante ; Renata Helena Branco Arnandes ; Ricardo da Fonseca ; Roberto Carvalheiro ; Sarah Figueiredo Martins Bonilha
Associated grant(s):16/21454-8 - Genomic regions associated with feed efficiency indicator traits in an experimental Nellore cattle population, PUB.ART
16/19629-4 - Genome-Wide Association Study for Indicator Traits of Sexual Precocity in Nellore Cattle, PUB.ART
Associated scholarship(s):16/21201-2 - Mapping and characterization of eQTL associated with meat fatty acids in Nelore cattle, BP.PD
16/24227-2 - Application of machine learning methods on the genomic analysis for reproductive traits in Nelore cattle, BP.DR
16/23539-0 - Genetic evaluation in the presence of genotype-environment interaction in Nellore cattle: application of genomic tools, BP.PD
+ associated scholarships 16/24228-9 - Genomic wide association study for feed efficiency traits in Nellore cattle breeding programs, BP.MS
15/25304-8 - Genome-wide association and genomic selection study for fatty acid profile using haplotypes in Nellore cattle, BP.DR
16/02366-0 - SEARCH FOR CAUSAL STRUCTURES USING GRAPHICAL MODELS IN NELORE CATTLE, BP.DR
15/25356-8 - Estimation of genotype-environment interaction using genomic reaction norm and analysis of gene network for reproductive traits in Nellore cattle, BP.DR
15/06140-4 - Using single-step methodology for estimating genomic values of economic interest characteristics in Nellore cattle, BP.PD
14/11537-8 - Strategies for applying genomic selection in beef cattle breeding programs, BP.PD
14/00779-0 - Semi-parametric statistical models for complex traits analysis using genomic data from Nelore cattle, BP.DR
13/25910-0 - Assessment strategies genotyping in situations of uncertainty of paternity and its impact on the evaluation genomic in beef cattle, BP.DR
13/26264-4 - Effect of using different criteria for quality control of genotypes in studies of association and genome-wide selection, BP.MS
13/21845-9 - Use of single-step methodology for genomic values estimation of economic interest characteristics in Nellore cattle, BP.PD
13/25621-8 - Normal/independent distributions in genome wide prediction of complex traits, BP.PD
13/01228-5 - Genomic selection for feed efficiency traits in Nellore cattle, BP.DR
13/09190-7 - Differential expression of genes related of meat tenderness in Nellore cattle, BP.DR
12/24600-4 - Identification of signature selection in three lineages of Nellore cattle selected for growth, BP.DR
13/00035-9 - Detection of QTLs and search for causal mutations in candidate gene for meat tenderness in Nellore cattle, BP.DR
13/00848-0 - Genomic selection for sexual precocity in Nelore heifers, BP.DR
12/21969-7 - Use of genomic information for genetic improvement of traits in beef cattle Nellore, BP.DR
10/14580-0 - Association study among single nucleotide polymorphisms with carcass and meat traits in Nellore cattle using high density painels, BP.MS
10/14675-1 - Association study among carcass and meat traits with growth traits in Nelore cattle, BP.MS
11/14850-0 - Proteins characterization µ-calpain, m-calpain and calpastatin and their relation with the quality characteristics of Nelore (Bos indicus) selected for production meat., BP.MS
11/09393-0 - Study of different selective genotyping strategies and comparison of models to predict genomic values using simulated data, BP.PD
11/01811-7 - Genomic selection for traits related to reproductive efficiency in Nelore heifers, BP.DR - associated scholarships

Abstract

Beef cattle production is an important socioeconomic activity for Brazil and the World. To date, in the world meat market, there is a tendency to value differentiated meat products (i.e., value added-products), in terms of meat organoleptic traits and consequences of meat consumption on human health. Also, there is a growing concern about the impact of livestock production systems on the environment and the competition between humans and livestock species for the same sources of food like grains and supplements. In this world scenario, in order to increase profitability of beef cattle production maintaining sustainability, traits associated to carcass and meat quality, as well as to feed conversion would be relevant. Until now, meat and carcass traits and those associated with feed conversion have not been considered in beef cattle breeding programs, probably because of the high costs and difficulties for recording these traits. Recently, there are some Brazilian research institutions that have collected records for these traits, mainly carcass and meat traits. However, studies in the genetic quantitative area reporting genetic parameter estimates for these traits are rare. Moreover, in general, the samples are small since is not to easy obtain these traits under field conditions (no experimental data). Thus, before including traits associated to carcass and meat quality, as well as feed conversion, in beef cattle breeding programs, it is necessary to have genetic parameter estimates for these traits obtained from various different samples. Important advances in molecular genetic techniques, as the high density SNP panel, will allow significant genetic gains, mainly, for traits that are costly and difficulty to measure, as is the case of carcass, meat and feed conversion traits. However, methodologies that allow to the inclusion of genomic data in Brazilian beef cattle genetic evaluation are still necessary. The objectives of this project are to build a dataset with carcass, meat and feed conversion traits, as well as to use data from others economic important traits that are normally recorded in beef cattle breeding programs, as growth and reproductive traits; to search for DNA polymorphisms associated to these traits; and to develop methodologies and software to apply genomic selection. To achieve these objectives the following topics will be developed in the project: a) Quantitative genetic analyses of carcass, meat and feed conversion traits and their associations with others traits of economic importance; b) Association studies between single nucleotide polymorphisms (SNP) and economic important traits in Nelore cattle; c) Expression studies of genes associated to carcass, meat and feed conversion traits; d) Development and implementation of an algorithm to simulate molecular data to perform genetic evaluation using SNP´s; f) Genomic selection for carcass, meat and feed conversion traits in Nelore cattle. (AU)

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Scientific publications (86)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
BALDASSINI, W. A.; CHARDULO, L. A. L.; SILVA, J. A. V.; MALHEIROS, J. M.; DIAS, V. A. D.; ESPIGOLAN, R.; BALDI, F. S.; ALBUQUERQUE, L. G.; FERNANDES, T. T.; PADILHA, P. M.. Meat quality traits of Nellore bulls according to different degrees of backfat thickness: a multivariate approach. ANIMAL PRODUCTION SCIENCE, v. 57, n. 2, p. 363-370, . (09/16118-5, 11/14850-0, 10/51332-5)
HERMISDORFF, ISIS DA COSTA; SOLAR DIAZ, IARA DEL PILAR; FERREIRA DE CAMARGO, GREGORIO MIGUEL; DE ALBUQUERQUE, LUCIA GALVAO; COSTA, RAPHAEL BERMAL. Effect of genomic X-chromosome regions on Nelore bull fertility. JOURNAL OF APPLIED GENETICS, . (09/16118-5)
BRAGA MAGALHAES, ANA FABRICIA; SCHENKEL, FLAVIO SCHRAMM; GARCIA, DIOGO ANASTACIO; MANSAN GORDO, DANIEL GUSTAVO; TONUSSI, RAFAEL LARA; ESPIGOLAN, RAFAEL; DE OLIVEIRA SILVA, RAFAEL MEDEIROS; BRAZ, CAMILA URBANO; FERNANDES JUNIOR, GERARDO ALVES; BALDI, FERNANDO; et al. Genomic selection for meat quality traits in Nelore cattle. MEAT SCIENCE, v. 148, p. 32-37, . (12/21969-7, 09/16118-5)
COSTA, RAPHAEL B.; CAMARGO, GREGORIO M. F.; DIAZ, IARA D. P. S.; IRANO, NATALIA; DIAS, MARINA M.; CARVALHEIRO, ROBERTO; BOLIGON, ARIONE A.; BALDI, FERNANDO; OLIVEIRA, HENRIQUE N.; TONHATI, HUMBERTO; et al. Genome-wide association study of reproductive traits in Nellore heifers using Bayesian inference. GENETICS SELECTION EVOLUTION, v. 47, . (09/16118-5, 11/01811-7)
ALVES, JACKELINE SANTOS; DIAZ, IARA DEL PILAR SOLAR; DA CRUZ, VALDECY APARECIDA ROCHA; BASTOS, MARISA SILVA; DE OLIVEIRA, LOUISE SARMENTO MARTINS; DE ALBUQUERQUE, LUCIA GALVAO; DE CAMARGO, GREGORIO MIGUEL FERREIRA; COSTA, RAPHAEL BERMAL. The effect of mitochondrial DNA polymorphisms on cattle reproduction. MOLECULAR BIOLOGY REPORTS, v. 48, n. 1, . (18/20026-8, 17/10630-2, 09/16118-5)
MALHEIROS, JESSICA MORAES; ENRIQUEZ-VALENCIA, CRUZ ELENA; DE VASCONCELOS SILVA, JOSINEUDSON AUGUSTO I. I.; CURI, ROGERIO ABDALLAH; DE OLIVEIRA, HENRIQUE NUNES; DE ALBUQUERQUE, LUCIA GALVAO; LOYOLA CHARDULO, LUIS ARTUR. Carcass and meat quality of Nellore cattle (Bos taurus indicus) belonging to the breeding programs. LIVESTOCK SCIENCE, v. 242, . (15/13021-1, 09/16118-5)
BRAGA MAGALHAES, ANA FABRICIA; DE ALMEIDA TEIXEIRA, GUSTAVO HENRIQUE; HERRERA RIOS, ANA CRISTINA; DOS SANTOS SILVA, DANIELLY BERALDO; MACEDO MOTA, LUCIO FLAVIO; MAGALHAES MUNIZ, MARIA MALANE; MEDEIROS DE MORAIS, CAMILO DE LELIS; GOMES DE LIMA, KASSIO MICHELL; CUNHA JUNIOR, LUIS CARLOS; BALDI, FERNANDO; et al. Prediction of meat quality traits in Nelore cattle by near-infrared reflectance spectroscopy. JOURNAL OF ANIMAL SCIENCE, v. 96, n. 10, p. 4229-4237, . (09/16118-5)
BRAZ, CAMILA URBANO; TAYLOR, JEREMY FRANCIS; DECKER, JARED EGAN; BRESOLIN, TIAGO; ESPIGOLAN, RAFAEL; GARCIA, DIOGO ANASTACIO; MANSAN GORDO, DANIEL GUSTAVO; BRAGA MAGALHAES, ANA FABRICIA; DE ALBUQUERQUE, LUCIA GALVDO; DE OLIVEIRA, HENRIQUE NUNES. Polymorphism analysis in genes associated with meat tenderness in Nelore cattle. META GENE, v. 18, p. 73-78, . (09/16118-5, 14/23013-3, 13/00035-9)
MOTA, LUCIO F. M.; LOPES, FERNANDO B.; FERNANDES JUNIOR, GERARDO A.; ROSA, GUILHERME J. M.; MAGALHAES, ANA F. B.; CARVALHEIRO, ROBERTO; ALBUQUERQUE, LUCIA G.. Genome-wide scan highlights the role of candidate genes on phenotypic plasticity for age at first calving in Nellore heifers. SCIENTIFIC REPORTS, v. 10, n. 1, . (09/16118-5, 15/25356-8, 17/02291-3)
SIMIELLI FONSECA, LARISSA FERNANDA; JOVINO GIMENEZ, DANIELE FERNANDA; DOS SANTOS SILVA, DANIELLY BERALDO; BARTHELSON, ROGER; BALDI, FERNANDO; FERRO, JESUS APARECIDO; ALBUQUERQUE, LUCIA GALVAO. Differences in global gene expression in muscle tissue of Nellore cattle with divergent meat tenderness. BMC Genomics, v. 18, . (09/16118-5, 13/09190-7)
DIAS, M. M.; CANOVAS, A.; MANTILLA-ROJAS, C.; RILEY, D. G.; LUNA-NEVAREZ, P.; COLEMAN, S. J.; SPEIDEL, S. E.; ENNS, R. M.; ISLAS-TREJO, A.; MEDRANO, J. F.; et al. SNP detection using RNA-sequences of candidate genes associated with puberty in cattle. Genetics and Molecular Research, v. 16, n. 1, . (09/16118-5, 11/21241-0)
CEACERO, THAIS MATOS; ZERLOTTI MERCADANTE, MARIA EUGENIA; DOS SANTOS GONCALVES CYRILLO, JOSLAINE NOELY; CANESIN, ROBERTA CARRILHO; MARTINS BONILHA, SARAH FIGUEIREDO; DE ALBUQUERQUE, LUCIA GALVAO. Phenotypic and Genetic Correlations of Feed Efficiency Traits with Growth and Carcass Traits in Nellore Cattle Selected for Postweaning Weight. PLoS One, v. 11, n. 8, . (09/16118-5)
SILVA, R. M. O.; FRAGOMENI, B. O.; LOURENCO, D. A. L.; MAGALHAES, A. F. B.; IRANO, N.; CARVALHEIRO, R.; CANESIN, R. C.; MERCADANTE, M. E. Z.; BOLIGON, A. A.; BALDI, F. S.; et al. Accuracies of genomic prediction of feed efficiency traits using different prediction and validation methods in an experimental Nelore cattle population. JOURNAL OF ANIMAL SCIENCE, v. 94, n. 9, p. 3613-3623, . (09/16118-5, 13/01228-5)
REGATIERI, INAE CRISTINA; BOLIGON, ARIONE AUGUSTI; COSTA, RAPHAEL BERMAL; PABLOS DE SOUZA, FABIO RICARDO; BALDI, FERNANDO; TAKADA, LUCIANA; VENTURINI, GUILHERME COSTA; FERREIRA DE CAMARGO, GREGORIO MIGUEL; FERNANDES JUNIOR, GERARDO ALVES; TONHATI, HUMBERTO; et al. Association between single nucleotide polymorphisms and sexual precocity in Nellore heifers. Animal Reproduction Science, v. 177, p. 88-96, . (09/16118-5, 10/13691-3)
DAMASCENO CARVALHO, CAIO VICTOR; HERMISDORFF, ISIS DA COSTA; SOUZA, ISADORA SARAIVA; BORGES JUNQUEIRA, GLEB STRAUSS; BRAGA MAGALHAES, ANA FABRICIA; SIMIELLI FONSECA, LARISSA FERNANDA; DE ALBUQUERQUE, LUCIA GALVAO; TONHATI, HUMBERTO; CARVALHEIRO, ROBERTO; FERREIRA DE CAMARGO, GREGORIO MIGUEL; et al. Influence of X-chromosome markers on reproductive traits of beef cattle. LIVESTOCK SCIENCE, v. 220, p. 152-157, . (09/16118-5)
BRESOLIN, TIAGO; PASSAFARO, TIAGO LUCIANO; BRAZ, CAMILA URBANO; CARVALHO ALVES, ANDERSON ANTONIO; CARVALHEIRO, ROBERTO; LOYOLA CHARDULO, LUIZ ARTUR; DE MAGALHAES ROSA, GUILHERME JORDAO; DE ALBUQUERQUE, LUCIA GALVAO. Investigating potential causal relationships among carcass and meat quality traits using structural equation model in Nellore cattle. MEAT SCIENCE, v. 187, p. 7-pg., . (09/16118-5, 16/02366-0, 17/18779-5)
MAIORANO, AMANDA MARCHI; CARDOSO, DIERCLES FRANCISCO; CARVALHEIRO, ROBERTO; FERNANDES JUNIOR, GERARDO ALVES; DE ALBUQUERQUE, LUCIA GALVAO; DE OLIVEIRA, HENRIQUE NUNES. Signatures of selection in Nelore cattle revealed by whole-genome sequencing data. Genomics, v. 114, n. 2, p. 12-pg., . (17/10630-2, 09/16118-5)
GARCIA, D. A.; ROSA, G. J. M.; VALENTE, B. D.; CARVALHEIRO, R.; FERNANDES JUNIOR, G. A.; ALBUQUERQUE, L. G.. Evaluation of longevity modeling censored records in Nellore. ANIMAL, v. 11, n. 12, p. 2113-2119, . (09/16118-5, 09/15010-6)
ABOUJAOUDE, CAROLYN; BERTON, MARIANA PIATTO; DE OLIVEIRA, HENRIQUE NUNES; ESPIGOLAN, RAFAEL; TONUSSI, RAFAEL LARA; DE OLIVEIRA SILVA, RAFAEL MEDEIROS; BALDI, FERNANDO. Genetic correlation estimates between beef fatty acid profile with meat and carcass traits in Nellore cattle finished in feedlot. JOURNAL OF APPLIED GENETICS, v. 58, n. 1, p. 123-132, . (09/16118-5, 11/21241-0, 12/23979-0)
GORDO, D. G. M.; ESPIGOLAN, R.; TONUSSI, R. L.; JUNIOR, G. A. F.; BRESOLIN, T.; BRAGA MAGALHAES, A. F.; FEITOSA, F. L.; BALDI, F.; CARVALHEIRO, R.; TONHATI, H.; et al. Genetic parameter estimates for carcass traits and visual scores including or not genomic information. JOURNAL OF ANIMAL SCIENCE, v. 94, n. 5, p. 1821-1826, . (09/16118-5, 14/11537-8)
DE LEMOS, MARCOS VINICIUS ANTUNES; PERIPOLLI, ELISA; BERTON, MARIANA PIATTO; BRAGA FEITOSA, FABIELE LOISE; OLIVIERI, BIANCA FERREIRA; STAFUZZA, NEDENIA BONVINO; TONUSSI, RAFAEL LARA; KLUSKA, SABRINA; JUSTINO CHIAIA, HERMENEGILDO LUCAS; MUELLER, LENISE; et al. Association study between copy number variation and beef fatty acid profile of Nellore cattle. JOURNAL OF APPLIED GENETICS, v. 59, n. 2, p. 203-223, . (09/16118-5, 13/11853-4)
SIMIELLI FONSECA, LARISSA FERNANDA; DOS SANTOS SILVA, DANIELLY BERALDO; JOVINO GIMENEZ, DANIELE FERNANDA; BALDI, FERNANDO; FERRO, JESUS APARECIDO; LOYOLA CHARDULO, LUIS ARTUR; DE ALBUQUERQUE, LUCIA GALVAO. Gene expression profiling and identification of hub genes in Nellore cattle with different marbling score levels. Genomics, v. 112, n. 1, p. 873-879, . (09/16118-5, 13/09190-7)
MONTES, DONICER E.; BRAZ, CAMILA U.; RIBEIRO, ANDRE M. F.; CAVANI, LIGIA; BARBERO, MARINA M. D.; ALBUQUERQUE, LUCIA G.; CURI, ROGERIO A.; OLIVEIRA, HENRIQUE N.. Selection signatures in candidate genes and QTL for reproductive traits in Nellore heifers. Animal Reproduction Science, v. 207, p. 1-8, . (10/13691-3, 09/16118-5)
DOS SANTOS SILVA, DANIELLY BERALDO; SIMIELLI FONSECA, LARISSA FERNANDA; PINHEIRO, DANIEL GUARIZ; MAGALHAES MUNIZ, MARIA MALANE; BRAGA MAGALHAES, ANA FABRICIA; BALDI, FERNANDO; FERRO, JESUS APARECIDO; LOYOLA CHARDULO, LUIS ARTUR; DE ALBUQUERQUE, LUCIA GALVAO. Prediction of hub genes associated with intramuscular fat content in Nelore cattle. BMC Genomics, v. 20, . (09/16118-5, 15/16850-9)
GORDO, DANIEL GUSTAVO M.; ESPIGOLAN, RAFAEL; BRESOLIN, TIAGO; FERNANDES JUNIOR, GERARDO A.; MAGALHAES, ANA F. B.; BRAZ, CAMILA U.; FERNANDES, WILLIAM BRUNO; BALDI, FERNANDO; ALBUQUERQUE, LUCIA G.. Genetic analysis of carcass and meat quality traits in Nelore cattle. JOURNAL OF ANIMAL SCIENCE, v. 96, n. 9, p. 3558-3564, . (09/16118-5)
FERNANDES JUNIOR, GERARDO ALVES; GARCIA, DIOGO ANASTACIO; HORTOLANI, BRUNA; DE ALBUQUERQUE, LUCIA GALVAO. Phenotypic relationship of female sexual precocity with production and reproduction traits in beef cattle using multivariate statistical techniques. Italian Journal of Animal Science, v. 18, n. 1, p. 182-188, . (13/25621-8, 09/16118-5)
MOTA, L. F. M.; FERNANDES, JR., G. A.; HERRERA, A. C.; SCALEZ, D. C. B.; ESPIGOLAN, R.; MAGALHAES, A. F. B.; CARVALHEIRO, R.; BALDI, F.; ALBUQUERQUE, L. G.. Genomic reaction norm models exploiting genotype x environment interaction on sexual precocity indicator traits in Nellore cattle. ANIMAL GENETICS, v. 51, n. 2, p. 210-223, . (17/02291-3, 09/16118-5, 15/25356-8)
DE OLIVEIRA SILVA, RAFAEL MEDEIROS; STAFUZZA, NEDENIA BONVINO; FRAGOMENI, BRENO DE OLIVEIRA; FERREIRA DE CAMARGO, GREGORIO MIGUEL; CEACERO, THAIS MATOS; DOS SANTOS GONCALVES CYRILLO, JOSLAINE NOELY; BALDI, FERNANDO; BOLIGON, ARIONE AUGUSTI; ZERLOTTI MERCADANTE, MARIA EUGENIA; LOURENCO, DANIELA LINO; et al. Genome-Wide Association Study for Carcass Traits in an Experimental Nelore Cattle Population. PLoS One, v. 12, n. 1, . (09/16118-5, 13/01228-5)
JUSTINO CHIAIA, HERMENEGILDO LUCAS; PERIPOLI, ELISA; DE OLIVEIRA SILVA, RAFAEL MEDEIROS; ABOUJAOUDE, CAROLYN; BRAGA FEITOSA, FABIELE LOISE; ANTUNES DE LEMOS, MARCOS VINICIUS; BERTON, MARIANA PIATTO; OLIVIERI, BIANCA FERREIRA; ESPIGOLAN, RAFAEL; TONUSSI, RAFAEL LARA; et al. Genomic prediction for beef fatty acid profile in Nellore cattle. MEAT SCIENCE, v. 128, p. 60-67, . (09/16118-5)
FERNANDES JUNIOR, G. A.; COSTA, R. B.; DE CAMARGO, G. M. F.; CARVALHEIRO, R.; ROSA, G. J. M.; BALDI, F.; GARCIA, D. A.; GORDO, D. G. M.; ESPIGOLAN, R.; TAKADA, L.; et al. Genome scan for postmortem carcass traits in Nellore cattle. JOURNAL OF ANIMAL SCIENCE, v. 94, n. 10, p. 4087-4095, . (09/16118-5, 15/06140-4)
IRANO, NATALIA; FERREIRA DE CAMARGO, GREGORIO MIGUEL; COSTA, RAPHAEL BERMAL; NASCIMENTO TERAKADO, ANA PAULA; BRAGA MAGALHAES, ANA FABRICIA; DE OLIVEIRA SILVA, RAFAEL MEDEIROS; DIAS, MARINA MORTATI; BIGNARDI, ANNAIZA BRAGA; BALDI, FERNANDO; CARVALHEIRO, ROBERTO; et al. Genome-Wide Association Study for Indicator Traits of Sexual Precocity in Nellore Cattle. PLoS One, v. 11, n. 8, . (09/16118-5, 13/00848-0)
COSTA, RAPHAEL BERMAL; IRANO, NATALIA; SOLAR DIAZ, LARA DEL PILAR; TAKADA, LUCIANA; HERMISDORFF, ISIS DA COSTA; CARVALHEIRO, ROBERTO; BALDI, FERNANDO; DE OLIVEIRA, HENRIQUE NUNES; TONHATI, HUMBERTO; DE ALBUQUERQUE, LUCIA GALVA. Prediction of genomic breeding values for reproductive traits in Nellore heifers. Theriogenology, v. 125, p. 12-17, . (09/16118-5)
BERTON, MARIANA P.; FONSECA, LARISSA F. S.; GIMENEZ, DANIELA F. J.; UTEMBERGUE, BRUNO L.; CESAR, ALINE S. M.; COUTINHO, LUIZ L.; DE LEMOS, MARCOS VINICIUS A.; ABOUJAOUDE, CAROLYN; PEREIRA, ANGELICA S. C.; DE O SILVA, RAFAEL M.; et al. Gene expression profile of intramuscular muscle in Nellore cattle with extreme values of fatty acid. BMC Genomics, v. 17, . (09/16118-5, 12/15098-3)
MAGALHAES, ANA F. B.; DE CAMARGO, GREGORIO M. F.; FERNANDES JUNIOR, GERARDO A.; GORDO, DANIEL G. M.; TONUSSI, RAFAEL L.; COSTA, RAPHAEL B.; ESPIGOLAN, RAFAEL; SILVA, RAFAEL M. DE O.; BRESOLIN, TIAGO; DE ANDRADE, WILLIAN B. F.; et al. Genome-Wide Association Study of Meat Quality Traits in Nellore Cattle. PLoS One, v. 11, n. 6, . (09/16118-5, 12/21969-7)
MELO, THAISE P.; TAKADA, LUCIANA; BALDI, FERNANDO; OLIVEIRA, HENRIQUE N.; DIAS, MARINA M.; NEVES, HAROLDO H. R.; SCHENKEL, FLAVIO S.; ALBUQUERQUE, LUCIA G.; CARVALHEIRO, ROBERTO. Assessing the value of phenotypic information from non-genotyped animals for QTL mapping of complex traits in real and simulated populations. BMC GENETICS, v. 17, . (09/16118-5, 14/09603-2, 13/17396-4)
BALDASSINI, WELDER ANGELO; BRAGA, CAMILA PEREIRA; LOYOLA CHARDULO, LUIS ARTUR; II VASCONCELOS SILVA, JOSINEUDSON AUGUSTO; MALHEIROS, JESSICA MORAES; DE ALBUQUERQUE, LUCIA GALVAO; FERNANDES, TALITA TANAKA; PADILHA, PEDRO DE MAGALHAES. Bioanalytical methods for the metalloproteomics study of bovine longissimus thoracis muscle tissue with different grades of meat tenderness in the Nellore breed (Bos indicus). Food Chemistry, v. 169, p. 65-72, . (09/16118-5, 11/14850-0, 10/51332-5)
BRAGA FEITOSA, FABIELI LOISE; CRAVO PEREIRA, ANGELICA SIMONE; AMORIM, SABRINA THAISE; PERIPOLLI, ELISA; DE OLIVEIRA SILVA, RAFAEL MEDEIROS; BRAZ, CAMILA URBANO; FERRINHO, ADRIELLE MATIAS; SCHENKEL, FLAVIO SCHRAMM; BRITO, LUIZ FERNANDO; ESPIGOLAN, RAFAEL; et al. Comparison between haplotype-based and individual snp-based genomic predictions for beef fatty acid profile in Nelore cattle. JOURNAL OF ANIMAL BREEDING AND GENETICS, v. 137, n. 5, p. 468-476, . (09/16118-5, 16/24085-3, 15/25304-8)
FERNANDES JUNIOR, GERARDO ALVES; DE OLIVEIRA, HENRIQUE NUNES; CARVALHEIRO, ROBERTO; CARDOSO, DIERCLES FRANCISCO; FONSECA, LARISSA FERNANDA SIMIELLI; VENTURA, RICARDO VIEIRA; DE ALBUQUERQUE, LUCIA GALVAO. Whole-genome sequencing provides new insights into genetic mechanisms of tropical adaptation in Nellore (Bos primigenius indicus). SCIENTIFIC REPORTS, v. 10, n. 1, . (09/16118-5, 19/12434-1, 18/10109-3, 18/20026-8, 17/10630-2)
HERMISDORFF, ISIS DA COSTA; SOLAR DIAZ, IARA DEL PILAR; FERREIRA DE CAMARGO, GREGORIO MIGUEL; DE ALBUQUERQUE, LUCIA GALVAO; COSTA, RAPHAEL BERMAL. Effect of genomic X-chromosome regions on Nelore bull fertility. JOURNAL OF APPLIED GENETICS, v. 62, n. 4, p. 655-659, . (09/16118-5)
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