Genomic tools to genetic improvement of direct economic important traits in Nelore cattle

• Grant number: 09/16118-5
• Support type: Research Projects - Thematic Grants
• Duration: February 01, 2011 - January 31, 2017
• Field of knowledge: Agronomical Sciences - Animal Husbandry
• Principal Investigator: Lucia Galvão de Albuquerque
• Grantee: Lucia Galvão de Albuquerque
• Home Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil
• Co-Principal Investigators: Maria Eugênia Zerlotti Mercadante
• Assoc. researchers: Fabio Ricardo Pablos de Souza ; Fernando Flores Cardoso ; Fernando Sebastián Baldi Rey ; Flávio Schramm Schenkel ; Guilherme Jordão de Magalhães Rosa ; Henrique Nunes de Oliveira ; Humberto Tonhati ; Jesus Aparecido Ferro ; José Fernando Garcia ; Joslaine Noely dos Santos Goncalves Cyrillo ; Luis Artur Loyola Chardulo ; Maria Eugênia Zerlotti Mercadante ; Renata Helena Branco Arnandes ; Ricardo da Fonseca ; Roberto Carvalheiro ; Sarah Figueiredo Martins Bonilha
• Associated grant(s): 16/21454-8 - Genomic regions associated with feed efficiency indicator traits in an experimental Nellore cattle population, PUB.ART; 16/19629-4 - Genome-Wide Association Study for indicator traits of sexual precocity in Nellore cattle, PUB.ART
• Associated scholarship(s): 16/21201-2 - Mapping and characterization of eQTL associated with meat fatty acids in Nelore cattle, BP.PD; 16/24227-2 - Application of machine learning methods on the genomic analysis for reproductive traits in Nelore cattle, BP.DR; 16/23539-0 - Genetic evaluation in the presence of genotype-environment interaction in Nellore cattle: application of genomic tools, BP.PD; + associated scholarships 16/24228-9 - Genomic wide association study for feed efficiency traits in Nellore cattle breeding programs, BP.MS; 15/25304-8 - Genome-wide association and genomic selection study for fatty acid profile using haplotypes in Nellore cattle, BP.DR; 16/02366-0 - Search for causal structures using graphical models in Nelore cattle, BP.DR; 15/25356-8 - Estimation of genotype-environment interaction using genomic reaction norm and analysis of gene network for reproductive traits in Nellore cattle, BP.DR; 15/06140-4 - Using single-step methodology for estimating genomic values of economic interest characteristics in Nellore cattle, BP.PD; 14/11537-8 - Strategies for applying genomic selection in beef cattle breeding programs, BP.PD; 14/00779-0 - Semi-parametric statistical models for complex traits analysis using genomic data from Nelore cattle, BP.DR; 13/26264-4 - Effect of using different criteria for quality control of genotypes in studies of association and genome-wide selection, BP.MS; 13/25910-0 - Assessment strategies genotyping in situations of uncertainty of paternity and its impact on the evaluation genomic in beef cattle, BP.DR; 13/21845-9 - Use of single-step methodology for genomic values estimation of economic interest characteristics in Nellore cattle, BP.PD; 13/25621-8 - Normal/independent distributions in genome wide prediction of complex traits, BP.PD; 13/01228-5 - Genomic selection for feed efficiency traits in Nellore cattle, BP.DR; 13/09190-7 - Differential expression of genes related of meat tenderness in Nellore cattle, BP.DR; 12/24600-4 - Identification of signature selection in three lineages of Nellore cattle selected for growth, BP.DR; 13/00035-9 - Detection of QTLs and search for causal mutations in candidate gene for meat tenderness in Nellore cattle, BP.DR; 13/00848-0 - Genomic selection for sexual precocity in Nelore heifers, BP.DR; 12/21969-7 - Use of genomic information for genetic improvement of traits in beef cattle Nellore, BP.DR; 10/14580-0 - Association study among single nucleotide polymorphisms with carcass and meat traits in Nellore cattle using high density painels, BP.MS; 10/14675-1 - Association study among carcass and meat traits with growth traits in Nelore cattle, BP.MS; 11/14850-0 - Proteins characterization µ-calpain, m-calpain and calpastatin and their relation with the quality characteristics of Nelore (Bos indicus) selected for production meat, BP.MS; 11/09393-0 - Study of different selective genotyping strategies and comparison of models to predict genomic values using simulated data, BP.PD; 11/01811-7 - Genomic selection for traits related to reproductive efficiency in Nelore heifers, BP.DR - associated scholarships

Abstract

Beef cattle production is an important socioeconomic activity for Brazil and the World. To date, in the world meat market, there is a tendency to value differentiated meat products (i.e., value added-products), in terms of meat organoleptic traits and consequences of meat consumption on human health. Also, there is a growing concern about the impact of livestock production systems on the environment and the competition between humans and livestock species for the same sources of food like grains and supplements. In this world scenario, in order to increase profitability of beef cattle production maintaining sustainability, traits associated to carcass and meat quality, as well as to feed conversion would be relevant. Until now, meat and carcass traits and those associated with feed conversion have not been considered in beef cattle breeding programs, probably because of the high costs and difficulties for recording these traits. Recently, there are some Brazilian research institutions that have collected records for these traits, mainly carcass and meat traits. However, studies in the genetic quantitative area reporting genetic parameter estimates for these traits are rare. Moreover, in general, the samples are small since is not to easy obtain these traits under field conditions (no experimental data). Thus, before including traits associated to carcass and meat quality, as well as feed conversion, in beef cattle breeding programs, it is necessary to have genetic parameter estimates for these traits obtained from various different samples. Important advances in molecular genetic techniques, as the high density SNP panel, will allow significant genetic gains, mainly, for traits that are costly and difficulty to measure, as is the case of carcass, meat and feed conversion traits. However, methodologies that allow to the inclusion of genomic data in Brazilian beef cattle genetic evaluation are still necessary. The objectives of this project are to build a dataset with carcass, meat and feed conversion traits, as well as to use data from others economic important traits that are normally recorded in beef cattle breeding programs, as growth and reproductive traits; to search for DNA polymorphisms associated to these traits; and to develop methodologies and software to apply genomic selection. To achieve these objectives the following topics will be developed in the project: a) Quantitative genetic analyses of carcass, meat and feed conversion traits and their associations with others traits of economic importance; b) Association studies between single nucleotide polymorphisms (SNP) and economic important traits in Nelore cattle; c) Expression studies of genes associated to carcass, meat and feed conversion traits; d) Development and implementation of an algorithm to simulate molecular data to perform genetic evaluation using SNP´s; f) Genomic selection for carcass, meat and feed conversion traits in Nelore cattle. (AU)

Scientific publications

(54)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MONTES, DONICER E.; BRAZ, CAMILA U.; RIBEIRO, ANDRE M. F.; CAVANI, LIGIA; BARBERO, MARINA M. D.; ALBUQUERQUE, LUCIA G.; CURI, ROGERIO A.; OLIVEIRA, HENRIQUE N. Selection signatures in candidate genes and QTL for reproductive traits in Nellore heifers. Animal Reproduction Science, v. 207, p. 1-8, AUG 2019. Web of Science Citations: 0.

MELO, THAISE P.; FORTES, MARINA R. S.; FERNANDES JUNIOR, GERARDO A.; ALBUQUERQUE, LUCIA G.; CARVALHEIRO, ROBERTO. RAPID COMMUNICATION: Multi-breed validation study unraveled genomic regions associated with puberty traits segregating across tropically adapted breeds. JOURNAL OF ANIMAL SCIENCE, v. 97, n. 7, p. 3027-3033, JUL 2019. Web of Science Citations: 0.

PIERUCCI, JULIA CESTARI; TONHATI, HUMBERTO; DE ALBUQUERQUE, LUCIA GALVAO; CARDOSO, DIERCLES FRANCISCO; DE ABREU DOS SANTOS, DANIEL JORDAN; FREITAS, ANA CLAUDIA; DIAS BARBERO, MARINA MORTATI; FERREIRA DE CAMARGO, GREGORIO MIGUEL; BRAZ, CAMILA URBANO; GIMENES, LINDSAY UNNO. Amh Polymorphisms and their association with traits indicative of sexual precocity in nelore heifers. SEMINA-CIENCIAS AGRARIAS, v. 40, n. 4, p. 1489-1499, JUL-AUG 2019. Web of Science Citations: 0.

DOS SANTOS SILVA, DANIELLY BERALDO; SIMIELLI FONSECA, LARISSA FERNANDA; PINHEIRO, DANIEL GUARIZ; MAGALHAES MUNIZ, MARIA MALANE; BRAGA MAGALHAES, ANA FABRICIA; BALDI, FERNANDO; FERRO, JESUS APARECIDO; LOYOLA CHARDULO, LUIS ARTUR; DE ALBUQUERQUE, LUCIA GALVAO. Prediction of hub genes associated with intramuscular fat content in Nelore cattle. BMC Genomics, v. 20, JUN 25 2019. Web of Science Citations: 0.

DUITAMA CARRENO, LUIS ORLANDO; PESSOA, MATILDE DA CONCEICAO; ESPIGOLAN, RAFAEL; TAKADA, LUCIANA; BRESOLIN, TIAGO; CAVANI, LIGIA; BALDI, FERNANDO; CARVALHEIRO, ROBERTO; DE ALBUQUERQUE, LUCIA GALVAO; DA FONSECA, RICARDO. Genome Association Study for Visual Scores in Nellore Cattle Measured at Weaning. BMC Genomics, v. 20, FEB 20 2019. Web of Science Citations: 0.

BRAGA MAGALHAES, ANA FABRICIA; SCHENKEL, FLAVIO SCHRAMM; GARCIA, DIOGO ANASTACIO; MANSAN GORDO, DANIEL GUSTAVO; TONUSSI, RAFAEL LARA; ESPIGOLAN, RAFAEL; DE OLIVEIRA SILVA, RAFAEL MEDEIROS; BRAZ, CAMILA URBANO; FERNANDES JUNIOR, GERARDO ALVES; BALDI, FERNANDO; CARVALHEIRO, ROBERTO; BOLIGON, ARIONE AUGUSTI; DE OLIVEIRA, HENRIQUE NUNES; LOYOLA CHARDULO, LUIS ARTHUR; DE ALBUQUERQUE, LUCIA GALVAO. Genomic selection for meat quality traits in Nelore cattle. MEAT SCIENCE, v. 148, p. 32-37, FEB 2019. Web of Science Citations: 0.

COSTA, RAPHAEL BERMAL; IRANO, NATALIA; SOLAR DIAZ, LARA DEL PILAR; TAKADA, LUCIANA; HERMISDORFF, ISIS DA COSTA; CARVALHEIRO, ROBERTO; BALDI, FERNANDO; DE OLIVEIRA, HENRIQUE NUNES; TONHATI, HUMBERTO; DE ALBUQUERQUE, LUCIA GALVA. Prediction of genomic breeding values for reproductive traits in Nellore heifers. Theriogenology, v. 125, p. 12-17, FEB 2019. Web of Science Citations: 0.

DAMASCENO CARVALHO, CAIO VICTOR; HERMISDORFF, ISIS DA COSTA; SOUZA, ISADORA SARAIVA; BORGES JUNQUEIRA, GLEB STRAUSS; BRAGA MAGALHAES, ANA FABRICIA; SIMIELLI FONSECA, LARISSA FERNANDA; DE ALBUQUERQUE, LUCIA GALVAO; TONHATI, HUMBERTO; CARVALHEIRO, ROBERTO; FERREIRA DE CAMARGO, GREGORIO MIGUEL; COSTA, RAPHAEL BERMAL. Influence of X-chromosome markers on reproductive traits of beef cattle. LIVESTOCK SCIENCE, v. 220, p. 152-157, FEB 2019. Web of Science Citations: 0.

BRAZ, CAMILA U.; TAYLOR, JEREMY F.; BRESOLIN, TIAGO; ESPIGOLAN, RAFAEL; FEITOSA, FABIELI L. B.; CARVALHEIRO, ROBERTO; BALDI, FERNANDO; DE ALBUQUERQUE, LUCIA G.; DE OLIVEIRA, HENRIQUE N. Sliding window haplotype approaches overcome single SNP analysis limitations in identifying genes for meat tenderness in Nelore cattle. BMC GENETICS, v. 20, JAN 14 2019. Web of Science Citations: 0.

FERNANDES JUNIOR, GERARDO ALVES; GARCIA, DIOGO ANASTACIO; HORTOLANI, BRUNA; DE ALBUQUERQUE, LUCIA GALVAO. Phenotypic relationship of female sexual precocity with production and reproduction traits in beef cattle using multivariate statistical techniques. Italian Journal of Animal Science, v. 18, n. 1, p. 182-188, JAN 2 2019. Web of Science Citations: 0.

BRAZ, CAMILA URBANO; TAYLOR, JEREMY FRANCIS; DECKER, JARED EGAN; BRESOLIN, TIAGO; ESPIGOLAN, RAFAEL; GARCIA, DIOGO ANASTACIO; MANSAN GORDO, DANIEL GUSTAVO; BRAGA MAGALHAES, ANA FABRICIA; DE ALBUQUERQUE, LUCIA GALVDO; DE OLIVEIRA, HENRIQUE NUNES. Polymorphism analysis in genes associated with meat tenderness in Nelore cattle. META GENE, v. 18, p. 73-78, DEC 2018. Web of Science Citations: 0.

JUSTINO CHIAIA, HERMENEGILDO LUCAS; PERIPOLLI, ELISA; DE OLIVEIRA SILVA, RAFAEL MEDEIROS; BRAGA FEITOSA, FABIELE LOISE; ANTUNES DE LEMOS, MARCOS VINICIUS; BERTON, MARIANA PIATTO; OLIVIERI, BIANCA FERREIRA; ESPIGOLAN, RAFAEL; TONUSSI, RAFAEL LARA; MANSAN GORDO, DANIEL GUSTAVO; DE ALBUQUERQUE, LUCIA GALVAO; DE OLIVEIRA, HENRIQUE NUNES; FERRINHO, ADRIELLE MATHIAS; MUELLER, LENISE FREITAS; KLUSKA, SABRINA; TONHATI, HUMBERTO; CRAVO PEREIRA, ANGELICA SIMONE; AGUILAR, IGNACIO; BALDI, FERNANDO. Genomic prediction ability for beef fatty acid profile in Nelore cattle using different pseudo-phenotypes. JOURNAL OF APPLIED GENETICS, v. 59, n. 4, p. 493-501, NOV 2018. Web of Science Citations: 0.

VARGAS, GIOVANA; SCHENKEL, FLAVIO SCHRAMM; BRITO, LUIZ FERNANDO; DE REZENDE NEVES, HAROLDO HENRIQUE; MUNARI, DANISIO PRADO; BOLIGON, ARIONE AUGUSTI; CARVALHEIRO, ROBERTO. Unravelling biological biotypes for growth, visual score and reproductive traits in Nellore cattle via principal component analysis. LIVESTOCK SCIENCE, v. 217, p. 37-43, NOV 2018. Web of Science Citations: 0.

BRAGA MAGALHAES, ANA FABRICIA; DE ALMEIDA TEIXEIRA, GUSTAVO HENRIQUE; HERRERA RIOS, ANA CRISTINA; DOS SANTOS SILVA, DANIELLY BERALDO; MACEDO MOTA, LUCIO FLAVIO; MAGALHAES MUNIZ, MARIA MALANE; MEDEIROS DE MORAIS, CAMILO DE LELIS; GOMES DE LIMA, KASSIO MICHELL; CUNHA JUNIOR, LUIS CARLOS; BALDI, FERNANDO; CARVALHEIRO, ROBERTO; DE OLIVEIRA, HENRIQUE NUNES; LOYOLA CHARDULO, LUIS ARTUR; DE ALBUQUERQUE, LUCIA GALVAO. Prediction of meat quality traits in Nelore cattle by near-infrared reflectance spectroscopy. JOURNAL OF ANIMAL SCIENCE, v. 96, n. 10, p. 4229-4237, OCT 2018. Web of Science Citations: 1.

GORDO, DANIEL GUSTAVO M.; ESPIGOLAN, RAFAEL; BRESOLIN, TIAGO; FERNANDES JUNIOR, GERARDO A.; MAGALHAES, ANA F. B.; BRAZ, CAMILA U.; FERNANDES, WILLIAM BRUNO; BALDI, FERNANDO; ALBUQUERQUE, LUCIA G. Genetic analysis of carcass and meat quality traits in Nelore cattle. JOURNAL OF ANIMAL SCIENCE, v. 96, n. 9, p. 3558-3564, SEP 2018. Web of Science Citations: 1.

TERAKADO, A. P. N.; COSTA, R. B.; DE CAMARGO, G. M. F.; IRANO, N.; BRESOLIN, T.; TAKADA, L.; CARVALHO, C. V. D.; OLIVEIRA, H. N.; CARVALHEIRO, R.; BALDI, F.; DE ALBUQUERQUE, L. G. Genome-wide association study for growth traits in Nelore cattle. ANIMAL, v. 12, n. 7, p. 1358-1362, JUL 2018. Web of Science Citations: 3.

CARDOSO, DIERCLES F.; DE ALBUQUERQUE, LUCIA GALVAO; REIMER, CHRISTIAN; QANBARI, SABER; ERBE, MALENA; DO NASCIMENTO, ANDRE V.; VENTURINI, GUILHERME C.; BECKER SCALEZ, DAIANE C.; BALDI, FERNANDO; FERREIRA DE CAMARGO, GREGORIO M.; ZERLOTTI MERCADANTE, MARIA E.; DO SANTOS GONCALVES CYRILLO, JOSLAINE N.; SIMIANER, HENNER; TONHATI, HUMBERTO. Genome-wide scan reveals population stratification and footprints of recent selection in Nelore cattle. GENETICS SELECTION EVOLUTION, v. 50, MAY 2 2018. Web of Science Citations: 2.

DE LEMOS, MARCOS VINICIUS ANTUNES; PERIPOLLI, ELISA; BERTON, MARIANA PIATTO; BRAGA FEITOSA, FABIELE LOISE; OLIVIERI, BIANCA FERREIRA; STAFUZZA, NEDENIA BONVINO; TONUSSI, RAFAEL LARA; KLUSKA, SABRINA; JUSTINO CHIAIA, HERMENEGILDO LUCAS; MUELLER, LENISE; FERRINHO, ADRIELLI MATHIAS; CRAVO PREREIRA, ANGELICA SIMONE; DE OLIVEIRA, HENRIQUE NUNES; DE ALBUQUERQUE, LUCIA GALVO; BALDI, FERNANDO. Association study between copy number variation and beef fatty acid profile of Nellore cattle. JOURNAL OF APPLIED GENETICS, v. 59, n. 2, p. 203-223, MAY 2018. Web of Science Citations: 4.

TAKADA, LUCIANA; BARBERO, MARINA M. D.; OLIVEIRA, HENRIQUE N.; DE CAMARGO, GREGORIO M. F.; FERNANDES JUNIOR, JR., GERARDO A.; ASPILCUETA-BORQUIS, RUSBEL R.; SOUZA, FABIO R. P.; BOLIGON, ARIONE A.; MELO, THAISE P.; REGATIERI, INAE C.; FEITOSA, FABIELI L. B.; FONSECA, LARISSA F. S.; MAGALHAES, ANA F. B.; COSTA, RAPHAEL B.; ALBUQUERQUE, LUCIA G. Genomic association for sexual precocity in beef heifers using pre-selection of genes and haplotype reconstruction. PLoS One, v. 13, n. 1 JAN 2 2018. Web of Science Citations: 2.

ANTUNES DE LEMOS, MARCOS VINICIUS; BERTON, MARIANA PIATTO; FERREIRA DE CAMARGO, GREGORIO MIGUEL; PERIPOLLI, ELISA; DE OLIVEIRA SILVA, RAFAEL MEDEIROS; OLIVIERI, BIANCA FERREIRA; CESAR, ALINE S. M.; CRAVO PEREIRA, ANGELICA SIMONE; DE ALBUQUERQUE, LUCIA GALVAO; DE OLIVEIRA, HENRIQUE NUNES; TONHATI, HUMBERTO; BALDI, FERNANDO. Copy number variation regions in Nellore cattle: Evidences of environment adaptation. LIVESTOCK SCIENCE, v. 207, p. 51-58, JAN 2018. Web of Science Citations: 7.

OLIVEIRA, D. P.; LOURENCO, D. A. L.; TSURUTA, S.; MISZTAL, I.; SANTOS, D. J. A.; DE ARAUJO NETO, F. R.; ASPILCUETA-BORQUIS, R. R.; BALDI, F.; CARVALHEIRO, R.; DE CAMARGO, G. M. F.; ALBUQUERQUE, L. G.; TONHATI, H. Reaction norm for yearling weight in beef cattle using single-step genomic evaluation. JOURNAL OF ANIMAL SCIENCE, v. 96, n. 1, p. 27-34, JAN 2018. Web of Science Citations: 5.

ABOUJAOUDE, CAROLYN; CRAVO PEREIRA, ANGELICA SIMONE; BRAGA FEITOSA, FABIELI LOUISE; ANTUNES DE LEMOS, MARCOS VINICIUS; JUSTINO CHIAIA, HERMENEGILDO LUCAS; BERTON, MARIANA PIATTO; PERIPOLLI, ELISA; DE OLIVEIRA SILVA, RAFAEL MEDEIROS; FERRINHO, ADRIELLE MATHIAS; MUELLER, LENISE FREITAS; OLIVIERI, BIANCA FERREIRA; DE ALBUQUERQUE, LUCIA GALVAO; DE OLIVEIRA, HENRIQUE NUNES; TONHATI, HUMBERTO; ESPIGOLAN, RAFAEL; TONUSSI, RAFAEL; GORDO, DANIEL MANSAN; BRAGA MAGALHAES, ANA FABRICIA; BALDI, FERNANDO. Genetic parameters for fatty acids in intramuscular fat from feedlot-finished Nelore carcasses. ANIMAL PRODUCTION SCIENCE, v. 58, n. 2, p. 234-243, 2018. Web of Science Citations: 2.

SIMIELLI FONSECA, LARISSA FERNANDA; JOVINO GIMENEZ, DANIELE FERNANDA; DOS SANTOS SILVA, DANIELLY BERALDO; BARTHELSON, ROGER; BALDI, FERNANDO; FERRO, JESUS APARECIDO; ALBUQUERQUE, LUCIA GALVAO. Differences in global gene expression in muscle tissue of Nellore cattle with divergent meat tenderness. BMC Genomics, v. 18, DEC 4 2017. Web of Science Citations: 3.

GARCIA, D. A.; ROSA, G. J. M.; VALENTE, B. D.; CARVALHEIRO, R.; FERNANDES JUNIOR, G. A.; ALBUQUERQUE, L. G. Evaluation of longevity modeling censored records in Nellore. ANIMAL, v. 11, n. 12, p. 2113-2119, DEC 2017. Web of Science Citations: 0.

BARBERO, M. M. D.; SANTOS, D. J. A.; TAKADA, L.; DE CAMARGO, G. M. F.; FREITAS, A. C.; DIAZ, I. S. D. P.; DE SOUZA, F. R. P.; TONHATI, H.; ALBUQUERQUE, L. G.; OLIVEIRA, H. N. Prospecting polymorphisms in the PPP3CA and FABP4 genes and their association with early pregnancy probability in Nellore heifers. LIVESTOCK SCIENCE, v. 203, p. 76-81, SEP 2017. Web of Science Citations: 0.

AMARAL TEIXEIRA, DANIELA BARRETO; FERNANDES JUNIOR, GERARDO ALVES; DOS SANTOS SILVA, DANIELLY BERALDO; COSTA, RAPHAEL BERMAL; TAKADA, LUCIANA; MANSAN GORDO, DANIEL GUSTAVO; BRESOLIN, TIAGO; CARVALHEIRO, ROBERTO; BALDI, FERNANDO; DE ALBUQUERQUE, LUCIA GALVAO. Genomic analysis of stayability in Nellore cattle. PLoS One, v. 12, n. 6 JUN 7 2017. Web of Science Citations: 4.

JUSTINO CHIAIA, HERMENEGILDO LUCAS; PERIPOLI, ELISA; DE OLIVEIRA SILVA, RAFAEL MEDEIROS; ABOUJAOUDE, CAROLYN; BRAGA FEITOSA, FABIELE LOISE; ANTUNES DE LEMOS, MARCOS VINICIUS; BERTON, MARIANA PIATTO; OLIVIERI, BIANCA FERREIRA; ESPIGOLAN, RAFAEL; TONUSSI, RAFAEL LARA; MANSAN GORDO, DANIEL GUSTAVO; BRESOLIN, TIAGO; BRAGA MAGALHAES, ANA FABRICIA; FERNANDES JUNIOR, GERARDO ALVES; DE ALBUQUERQUE, LUCIA GALVAO; DE OLIVEIRA, HENRIQUE NUNES; MANGINI FURLAN, JOYCE DE JESUS; FERRINHO, ADRIELLE MATHIAS; MUELLER, LENISE FREITAS; TONHATI, HUMBERTO; CRAVO PEREIRA, ANGELICA SIMONE; BALDI, FERNANDO. Genomic prediction for beef fatty acid profile in Nellore cattle. MEAT SCIENCE, v. 128, p. 60-67, JUN 2017. Web of Science Citations: 4.

DE MELO, THAISE PINTO; FERREIRA DE CAMARGO, GREGORIO MIGUEL; DE ALBUQUERQUE, LUCIA GALVAO; CARVALHEIRO, ROBERTO. Genome-wide association study provides strong evidence of genes affecting the reproductive performance of Nellore beef cows. PLoS One, v. 12, n. 5 MAY 31 2017. Web of Science Citations: 10.

DIAS, M. M.; CANOVAS, A.; MANTILLA-ROJAS, C.; RILEY, D. G.; LUNA-NEVAREZ, P.; COLEMAN, S. J.; SPEIDEL, S. E.; ENNS, R. M.; ISLAS-TREJO, A.; MEDRANO, J. F.; MOORE, S. S.; FORTES, M. R. S.; NGUYEN, L. T.; VENUS, B.; DIAZ, I. S. D. P.; SOUZA, F. R. P.; FONSECA, L. F. S.; BALDI, F.; ALBUQUERQUE, L. G.; THOMAS, M. G.; OLIVEIRA, H. N. SNP detection using RNA-sequences of candidate genes associated with puberty in cattle. Genetics and Molecular Research, v. 16, n. 1 MAR 24 2017. Web of Science Citations: 6.

ABOUJAOUDE, CAROLYN; BERTON, MARIANA PIATTO; DE OLIVEIRA, HENRIQUE NUNES; ESPIGOLAN, RAFAEL; TONUSSI, RAFAEL LARA; DE OLIVEIRA SILVA, RAFAEL MEDEIROS; BALDI, FERNANDO. . JOURNAL OF APPLIED GENETICS, v. 58, n. 1, p. 123-132, FEB 2017. Web of Science Citations: 4.

REGATIERI, INAE CRISTINA; BOLIGON, ARIONE AUGUSTI; COSTA, RAPHAEL BERMAL; PABLOS DE SOUZA, FABIO RICARDO; BALDI, FERNANDO; TAKADA, LUCIANA; VENTURINI, GUILHERME COSTA; FERREIRA DE CAMARGO, GREGORIO MIGUEL; FERNANDES JUNIOR, GERARDO ALVES; TONHATI, HUMBERTO; DE OLIVEIRA, HENRIQUE NUNES; DE ALBUQUERQUE, LUCIA GALVAO. Association between single nucleotide polymorphisms and sexual precocity in Nellore heifers. Animal Reproduction Science, v. 177, p. 88-96, FEB 2017. Web of Science Citations: 5.

DE OLIVEIRA SILVA, RAFAEL MEDEIROS; STAFUZZA, NEDENIA BONVINO; FRAGOMENI, BRENO DE OLIVEIRA; FERREIRA DE CAMARGO, GREGORIO MIGUEL; CEACERO, THAIS MATOS; DOS SANTOS GONCALVES CYRILLO, JOSLAINE NOELY; BALDI, FERNANDO; BOLIGON, ARIONE AUGUSTI; ZERLOTTI MERCADANTE, MARIA EUGENIA; LOURENCO, DANIELA LINO; MISZTAL, IGNACY; DE ALBUQUERQUE, LUCIA GALVAO. Genome-Wide Association Study for Carcass Traits in an Experimental Nelore Cattle Population. PLoS One, v. 12, n. 1 JAN 24 2017. Web of Science Citations: 14.

ENRIQUEZ-VALENCIA, CRUZ ELENA; PEREIRA, GUILHERME LUIS; MALHEIROS, JESSICA MORAES; DE VASCONCELOS SILVA, JOSINEUDSON AUGUSTO I. I.; ALBUQUERQUE, LUCIA GALVAO; DE OLIVEIRA, HENRIQUE NUNES; LOYOLA CHARDULO, LUIS ARTUR; CURI, ROGERIO ABDALLAH. Effect of the g.98535683A > G SNP in the CAST gene on meat traits of Nellore beef cattle (Bos indicus) and their crosses with Bos taurus. MEAT SCIENCE, v. 123, p. 64-66, JAN 2017. Web of Science Citations: 5.

BALDASSINI, W. A.; CHARDULO, L. A. L.; SILVA, J. A. V.; MALHEIROS, J. M.; DIAS, V. A. D.; ESPIGOLAN, R.; BALDI, F. S.; ALBUQUERQUE, L. G.; FERNANDES, T. T.; PADILHA, P. M. Meat quality traits of Nellore bulls according to different degrees of backfat thickness: a multivariate approach. ANIMAL PRODUCTION SCIENCE, v. 57, n. 2, p. 363-370, 2017. Web of Science Citations: 3.

BERTON, MARIANA P.; FONSECA, LARISSA F. S.; GIMENEZ, DANIELA F. J.; UTEMBERGUE, BRUNO L.; CESAR, ALINE S. M.; COUTINHO, LUIZ L.; DE LEMOS, MARCOS VINICIUS A.; ABOUJAOUDE, CAROLYN; PEREIRA, ANGELICA S. C.; DE O SILVA, RAFAEL M.; STAFUZZA, NEDENIA B.; FEITOSA, FABIELI L. B.; CHIAIA, HERMENEGILDO L. J.; OLIVIERI, BIANCA F.; PERIPOLLI, ELISA; TONUSSI, RAFAEL L.; GORDO, DANIEL M.; ESPIGOLAN, RAFAEL; FERRINHO, ADRIELLE M.; MUELLER, LENISE F.; DE ALBUQUERQUE, LUCIA G.; DE OLIVEIRA, HENRIQUE N.; DUCKETT, SUSAN; BALDI, FEMANDO. Gene expression profile of intramuscular muscle in Nellore cattle with extreme values of fatty acid. BMC Genomics, v. 17, NOV 25 2016. Web of Science Citations: 12.

OLIVIERI, BIANCA FERREIRA; ZERLOTTI MERCADANTE, MARIA EUGENIA; DOS SANTOS GONCALVES CYRILLO, JOSLAINE NOELY; BRANCO, RENATA HELENA; MARTINS BONILHA, SARAH FIGUEIREDO; DE ALBUQUERQUE, LUCIA GALVAO; DE OLIVEIRA SILVA, RAFAEL MEDEIROS; BALDI, FERNANDO. Genomic Regions Associated with Feed Efficiency Indicator Traits in an Experimental Nellore Cattle Population. PLoS One, v. 11, n. 10 OCT 19 2016. Web of Science Citations: 11.

FERNANDES JUNIOR, G. A.; COSTA, R. B.; DE CAMARGO, G. M. F.; CARVALHEIRO, R.; ROSA, G. J. M.; BALDI, F.; GARCIA, D. A.; GORDO, D. G. M.; ESPIGOLAN, R.; TAKADA, L.; MAGALHAES, A. F. B.; BRESOLIN, T.; FEITOSA, F. L. B.; CHARDULO, L. A. L.; DE OLIVEIRA, H. N.; DE ALBUQUERQUE, L. G. Genome scan for postmortem carcass traits in Nellore cattle. JOURNAL OF ANIMAL SCIENCE, v. 94, n. 10, p. 4087-4095, OCT 2016. Web of Science Citations: 8.

SILVA, R. M. O.; FRAGOMENI, B. O.; LOURENCO, D. A. L.; MAGALHAES, A. F. B.; IRANO, N.; CARVALHEIRO, R.; CANESIN, R. C.; MERCADANTE, M. E. Z.; BOLIGON, A. A.; BALDI, F. S.; MISZTAL, I.; ALBUQUERQUE, L. G. Accuracies of genomic prediction of feed efficiency traits using different prediction and validation methods in an experimental Nelore cattle population. JOURNAL OF ANIMAL SCIENCE, v. 94, n. 9, p. 3613-3623, SEP 2016. Web of Science Citations: 15.

CEACERO, THAIS MATOS; ZERLOTTI MERCADANTE, MARIA EUGENIA; DOS SANTOS GONCALVES CYRILLO, JOSLAINE NOELY; CANESIN, ROBERTA CARRILHO; MARTINS BONILHA, SARAH FIGUEIREDO; DE ALBUQUERQUE, LUCIA GALVAO. Phenotypic and Genetic Correlations of Feed Efficiency Traits with Growth and Carcass Traits in Nellore Cattle Selected for Postweaning Weight. PLoS One, v. 11, n. 8 AUG 18 2016. Web of Science Citations: 13.

IRANO, NATALIA; FERREIRA DE CAMARGO, GREGORIO MIGUEL; COSTA, RAPHAEL BERMAL; NASCIMENTO TERAKADO, ANA PAULA; BRAGA MAGALHAES, ANA FABRICIA; DE OLIVEIRA SILVA, RAFAEL MEDEIROS; DIAS, MARINA MORTATI; BIGNARDI, ANNAIZA BRAGA; BALDI, FERNANDO; CARVALHEIRO, ROBERTO; DE OLIVEIRA, HENRIQUE NUNES; DE ALBUQUERQUE, LUCIA GALVAO. Genome-Wide Association Study for Indicator Traits of Sexual Precocity in Nellore Cattle. PLoS One, v. 11, n. 8 AUG 5 2016. Web of Science Citations: 17.

MAGALHAES, ANA F. B.; DE CAMARGO, GREGORIO M. F.; FERNANDES JUNIOR, GERARDO A.; GORDO, DANIEL G. M.; TONUSSI, RAFAEL L.; COSTA, RAPHAEL B.; ESPIGOLAN, RAFAEL; SILVA, RAFAEL M. DE O.; BRESOLIN, TIAGO; DE ANDRADE, WILLIAN B. F.; TAKADA, LUCIANA; FEITOSA, FABIELI L. B.; BALDI, FERNANDO; CARVALHEIRO, ROBERTO; CHARDULO, LUIS A. L.; DE ALBUQUERQUE, LUCIA G. Genome-Wide Association Study of Meat Quality Traits in Nellore Cattle. PLoS One, v. 11, n. 6 JUN 30 2016. Web of Science Citations: 24.

MELO, THAISE P.; TAKADA, LUCIANA; BALDI, FERNANDO; OLIVEIRA, HENRIQUE N.; DIAS, MARINA M.; NEVES, HAROLDO H. R.; SCHENKEL, FLAVIO S.; ALBUQUERQUE, LUCIA G.; CARVALHEIRO, ROBERTO. Assessing the value of phenotypic information from non-genotyped animals for QTL mapping of complex traits in real and simulated populations. BMC GENETICS, v. 17, JUN 21 2016. Web of Science Citations: 5.

VALENTE, TIAGO SILVA; BALDI, FERNANDO; SANT'ANNA, ALINE CRISTINA; ALBUQUERQUE, LUCIA GALVAO; RODRIGUES PARANHOS DA COSTA, MATEUS JOSE. Genome-Wide Association Study between Single Nucleotide Polymorphisms and Flight Speed in Nellore Cattle. PLoS One, v. 11, n. 6 JUN 14 2016. Web of Science Citations: 2.

GORDO, D. G. M.; ESPIGOLAN, R.; TONUSSI, R. L.; JUNIOR, G. A. F.; BRESOLIN, T.; BRAGA MAGALHAES, A. F.; FEITOSA, F. L.; BALDI, F.; CARVALHEIRO, R.; TONHATI, H.; DE OLIVEIRA, H. N.; CHARDULO, L. A. L.; DE ALBUQUERQUE, L. G. Genetic parameter estimates for carcass traits and visual scores including or not genomic information. JOURNAL OF ANIMAL SCIENCE, v. 94, n. 5, p. 1821-1826, MAY 2016. Web of Science Citations: 7.

LEMOS, MARCOS V. A.; JUSTINO CHIAIA, HERMENEGILDO LUCAS; BERTON, MARIANA PIATTO; FEITOSA, FABIELI L. B.; ABOUJAOUD, CAROLYN; CAMARGO, GREGORIO M. F.; PEREIRA, ANGELICA S. C.; ALBUQUERQUE, LUCIA G.; FERRINHO, ADRIELLE M.; MUELLER, LENISE F.; MAZALLI, MONICA R.; FURLAN, JOYCE J. M.; CARVALHEIRO, ROBERTO; GORDO, DANIEL M.; TONUSSI, RAFAEL; ESPIGOLAN, RAFAEL; DE OLIVEIRA SILVA, RAFAEL MEDEIROS; DE OLIVEIRA, HENRIQUE NUNES; DUCKETT, SUSAN; AGUILAR, IGNACIO; BALDI, FERNANDO. Genome-wide association between single nucleotide polymorphisms with beef fatty acid profile in Nellore cattle using the single step procedure. BMC Genomics, v. 17, MAR 9 2016. Web of Science Citations: 23.

FERNANDES JUNIOR, GERARDO A.; ROSA, GUILHERME J. M.; VALENTE, BRUNO D.; CARVALHEIRO, ROBERTO; BALDI, FERNANDO; GARCIA, DIOGO A.; GORDO, DANIEL G. M.; ESPIGOLAN, RAFAEL; TAKADA, LUCIANA; TONUSSI, RAFAEL L.; DE ANDRADE, WILLIAN B. F.; MAGALHAES, ANA F. B.; CHARDULO, LUIS A. L.; TONHATI, HUMBERTO; DE ALBUQUERQUE, LUCIA G. Genomic prediction of breeding values for carcass traits in Nellore cattle. GENETICS SELECTION EVOLUTION, v. 48, JAN 29 2016. Web of Science Citations: 17.

COSTA, RAPHAEL B.; CAMARGO, GREGORIO M. F.; DIAZ, IARA D. P. S.; IRANO, NATALIA; DIAS, MARINA M.; CARVALHEIRO, ROBERTO; BOLIGON, ARIONE A.; BALDI, FERNANDO; OLIVEIRA, HENRIQUE N.; TONHATI, HUMBERTO; ALBUQUERQUE, LUCIA G. Genome-wide association study of reproductive traits in Nellore heifers using Bayesian inference. GENETICS SELECTION EVOLUTION, v. 47, AUG 19 2015. Web of Science Citations: 14.

FONSECA, PATRICIA D. DA S.; DE SOUZA, FABIO R. P.; DE CAMARGO, GREGORIO M. F.; GIL, FERNANDA M. M.; CARDOSO, DIERCLES F.; ZETOUNI, LARISSA; BRAZ, CAMILA U.; BOLIGON, ARIONE A.; BRANCO, RENATA H.; DE ALBUQUERQUE, LUCIA G.; MERCADANTE, MARIA E. Z.; TONHATI, HUMBERTO. Association of ADIPOQ, OLR1 and PPARGC1A gene polymorphisms with growth and carcass traits in Nelore cattle. META GENE, v. 4, p. 1-7, JUN 2015. Web of Science Citations: 5.

CHIAIA, H. L. J.; DE LEMOS, M. V. A.; VENTURINI, G. C.; ABOUJAOUDE, C.; BERTON, M. P.; FEITOSA, F. B.; CARVALHEIRO, R.; ALBUQUERQUE, L. G.; DE OLIVEIRA, H. N.; BALDI, F. Genotype x environment interaction for age at first calving, scrotal circumference, and yearling weight in Nellore cattle using reaction norms in multitrait random regression models. JOURNAL OF ANIMAL SCIENCE, v. 93, n. 4, p. 1503-1510, APR 2015. Web of Science Citations: 8.

BALDASSINI, WELDER ANGELO; BRAGA, CAMILA PEREIRA; LOYOLA CHARDULO, LUIS ARTUR; II VASCONCELOS SILVA, JOSINEUDSON AUGUSTO; MALHEIROS, JESSICA MORAES; DE ALBUQUERQUE, LUCIA GALVAO; FERNANDES, TALITA TANAKA; PADILHA, PEDRO DE MAGALHAES. Bioanalytical methods for the metalloproteomics study of bovine longissimus thoracis muscle tissue with different grades of meat tenderness in the Nellore breed (Bos indicus). Food Chemistry, v. 169, p. 65-72, FEB 15 2015. Web of Science Citations: 12.

SIMIELLI FONSECA, LARISSA FERNANDA; JOVINO GIMENEZ, DANIELE FERNANDA; ZERLOTTI MERCADANTE, MARIA EUGENIA; MARTINS BONILHA, SARAH FIGUEIREDO; FERRO, JESUS APARECIDO; BALDI, FERNANDO; PABLOS DE SOUZA, FABIO RICARDO; DE ALBUQUERQUE, LUCIA GALVAO. Expression of genes related to mitochondrial function in Nellore cattle divergently ranked on residual feed intake. MOLECULAR BIOLOGY REPORTS, v. 42, n. 2, p. 559-565, FEB 2015. Web of Science Citations: 8.

DIAS, M. M.; SOUZA, F. R. P.; TAKADA, L.; FEITOSA, F. L. B.; COSTA, R. B.; DIAZ, I. D. P. S.; CARDOSO, D. F.; TONUSSI, R. L.; BALDI, F.; ALBUQUERQUE, L. G.; OLIVEIRA, H. N. Study of lipid metabolism-related genes as candidate genes of sexual precocity in Nellore cattle. Genetics and Molecular Research, v. 14, n. 1, p. 234-243, 2015. Web of Science Citations: 7.

ESPIGOLAN, R.; BALDI, F.; BOLIGON, A. A.; SOUZA, F. R. P.; FERNANDES JUNIOR, G. A.; GORDO, D. G. M.; VENTURINI, G. C.; DE CAMARGO, G. M. F.; FEITOSA, F. L. B.; GARCIA, D. A.; TONHATI, H.; CHARDULO, L. A. L.; OLIVEIRA, H. N.; ALBUQUERQUE, L. G. Associations between single nucleotide polymorphisms and carcass traits in Nellore cattle using high-density panels. Genetics and Molecular Research, v. 14, n. 3, p. 11133-11144, 2015. Web of Science Citations: 4.

TONUSSI, R. L.; ESPIGOLAN, R.; GORDO, D. G. M.; MAGALHAES, A. F. B.; VENTURINI, G. C.; BALDI, F.; DE OLIVEIRA, H. N.; CHARDULO, L. A. L.; TONHATI, H.; DE ALBUQUERQUE, L. G. Genetic association of growth traits with carcass and meat traits in Nellore cattle. Genetics and Molecular Research, v. 14, n. 4, p. 18713-18719, 2015. Web of Science Citations: 6.