Body composition and bone mineral density in users of the etonogestrel-releasing contraceptive implant

Author(s)

Modesto, Waleska ^{[1, 2]} ; DalAva, Natalia ^{[1, 2]} ; Monteiro, Ilza ^{[1, 2]} ; Bahamondes, Luis ^{[1, 2]}

Affiliation

^[1] Univ Estadual Campinas, UNICAMP, Human Reprod Unit, Dept Obstet & Gynaecol, Sch Med Sci, BR-13084971 Campinas, SP - Brazil

^[2] Univ Estadual Campinas, UNICAMP, Natl Inst Hormones & Womens Hlth, BR-13084971 Campinas, SP - Brazil

• Document type: Journal article
• Source: ARCHIVES OF GYNECOLOGY AND OBSTETRICS; v. 292, n. 6, p. 1387-1391, DEC 2015.
• Web of Science Citations: 9

Abstract

There is scarce information about bone mineral density (BMD) and body composition (BC) among users of the etonogestrel (ENG)-releasing implant. To evaluate BC and BMD in ENG-releasing implant users as compared to copper intrauterine device (Cu-IUD)-users. A prospective study was conducted on 75 users of both contraceptive methods. BMD was evaluated at femoral neck (FN) and lumbar spine (LS) (L1-L4) and BC at baseline and at 12 months after insertion. The mean (+/- SD) age was 30.4 +/- A 6.8 and 29.8 +/- A 8.4 years and body mass index (kg/m(2)) was 24.9 +/- A 4.1 and 24.6 +/- A 3.5 in ENG-releasing implant- and Cu-IUD-users, respectively. ENG-releasing implant users did not show significant differences on BMD at the LS and FN at 12 months of use. Furthermore, ENG-implant users had an increase in body weight at 12 months (p < 0.001) and an increase of 2 % in the percentage of body fat, when compared with Cu-IUD users. There was a significant increase in lean mass in ENG-implant users at 12 months (p = 0.020). No significant changes of BMD were seen after the first year of use among the ENG-releasing implant-users, albeit an increase of weight and fat mass was seen when compared to Cu-IUD users. (AU)

• FAPESP's process: 11/01554-4 - Body composition and bone mineral density in users of depot medroxyprogesterone acetate compared to CIU Tcu380A Intrauterine Device
• Grantee: Waleska Oliveira Modesto
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 12/12432-0 - Body composition and bone mineral density in userrs of the etonogestrel-releasing contraceptive implant (Implanon) compared to users of the intrauterine (IUD) TCu380A
• Grantee: Luis Guillermo Bahamondes
• Support Opportunities: Regular Research Grants