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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Absolute configuration assignment of an unusual homoisoflavanone from Polygonum ferrugineum using a combination of chiroptical methods

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Author(s):
Batista, Jr., Joao M. ; Wang, Bo [1] ; Castelli, Maria V. [2] ; Blanch, Ewan W. [3] ; Lopez, Silvia N. [2]
Total Authors: 5
Affiliation:
[1] BioTools Inc, Jupiter, FL 33458 - USA
[2] Univ Nacl Rosario, Farmacognosia, Fac Ciencias Bioquim & Farmaceut, RA-2000 Rosario, Santa Fe - Argentina
[3] RMIT Univ, Sch Appl Sci, Melbourne, Vic 3000 - Australia
Total Affiliations: 3
Document type: Journal article
Source: Tetrahedron Letters; v. 56, n. 44, p. 6142-6144, OCT 28 2015.
Web of Science Citations: 5
Abstract

The absolute configuration of the homoisoflavanone 5,7-dihydroxy-6-methoxy-3-(9-hydroxy-phenylmethyl)-chroman-4-one (1), found in Polygonum species, has been determined as 3R,9R by using a combination of electronic and vibrational chiroptical spectroscopic methods. The experimental spectra were interpreted with the aid of density functional theory calculations. The risks of relying upon a single method for stereochemical characterization of natural products are discussed. (C) 2015 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 14/25222-9 - Vibrational chiroptical spectroscopy for stereochemical characterization of small molecules and macromolecules
Grantee:João Marcos Batista Junior
Support Opportunities: Research Grants - Young Investigators Grants
FAPESP's process: 15/07089-2 - Vibrational chiroptical spectroscopy for stereochemical characterization of small molecules and macromolecules
Grantee:João Marcos Batista Junior
Support Opportunities: Scholarships in Brazil - Young Researchers