Zinc, Lithium and Magnesium Carbenoids: Chemical Properties and Relevant Applications in Organic Synthesis

Author(s)

Nishimura, Rodolfo H. V. ^{[1, 2]} ; Murie, Valter E. ^[1] ; Soldi, Rafael A. ^[1] ; Lopes, Joao L. C. ^[1] ; Clososki, Giuliano C. ^{[1, 2]}

Affiliation

^[1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Nucleo Pesquisa Prod Nat & Sintet, BR-14040903 Ribeirao Preto, SP - Brazil

^[2] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Quim, BR-14040901 Ribeirao Preto, SP - Brazil

• Document type: Journal article
• Source: Journal of the Brazilian Chemical Society; v. 26, n. 11, p. 2175-2188, NOV 2015.
• Web of Science Citations: 11

Abstract

Carbenoids are a class of highly reactive reagents that play an important role in modern organic synthesis. These species are very similar to singlet state carbenes since they have an ambiphilic character and react by a concerted mechanism allowing stereospecific transformations. Herein, we discuss these and other chemical aspects of zinc, lithium and magnesium carbenoids as well as relevant applications of these intermediates in organic synthesis. (AU)

• FAPESP's process: 14/20302-4 - Dinamics of the metabolism of the secondary metabolites from Asteraceae species biologically active through classical and recents mass spectrometric techniques and the poyencially developing of topical formulations for antinflammatory and analgesic use
• Grantee: João Luis Callegari Lopes
• Support Opportunities: BIOTA-FAPESP Program - Regular Research Grants
• FAPESP's process: 13/16972-1 - Application of green chemistry strategies for the preparation of tenofovir disoproxil fumarate
• Grantee: Rafael Augusto Soldi
• Support Opportunities: Scholarships in Brazil - Post-Doctoral