| Full text | |
| Author(s): Show less - |
Bernal, M. A.
[1]
;
Bordage, M. C.
[2, 3]
;
Brown, J. M. C.
[4, 5]
;
Davidkova, M.
[6]
;
Delage, E.
[7]
;
El Bitar, Z.
[8]
;
Enger, S. A.
[9]
;
Francis, Z.
[10]
;
Guatelli, S.
[11]
;
Ivanchenko, V. N.
[12, 13]
;
Karamitros, M.
[14]
;
Kyriakou, I.
[15]
;
Maigne, L.
[7]
;
Meylan, S.
[16]
;
Murakami, K.
[17]
;
Okada, S.
[17]
;
Payno, H.
[7]
;
Perrot, Y.
[7]
;
Petrovic, I.
[18]
;
Pham, Q. T.
[7]
;
Ristic-Fira, A.
[18]
;
Sasaki, T.
[17]
;
Stepan, V.
[6]
;
Tran, H. N.
[19, 20]
;
Villagrasa, C.
[16]
;
Incerti, S.
[19, 20, 21, 22]
Total Authors: 26
|
| Affiliation: Show less - | [1] Univ Estadual Campinas, Inst Fis Gleb Wataghin, BR-13081970 Campinas, SP - Brazil
[2] Univ Toulouse 3, CRCT, UMR 1037, INSERM, F-31062 Toulouse - France
[3] Univ Toulouse III Paul Sabatier, UMR 1037, CRCT, F-31000 Toulouse - France
[4] Monash Univ, Sch Phys & Astron, Melbourne, Vic 3004 - Australia
[5] Queens Univ Belfast, Sch Math & Phys, Belfast BT7 1NN, Antrim - North Ireland
[6] CAS, Dept Radiat Dosimetry, Inst Nucl Phys, Prague - Czech Republic
[7] Clermont Univ, CNRS, IN2P3, Lab Phys Corpusculaire, Aubiere - France
[8] Inst Pluridisciplinaire Hubert Curien, Strasbourg - France
[9] McGill Univ, Dept Oncol, Med Phys Unit, Montreal, PQ - Canada
[10] Uni St Jeseph, Dept Phys, Fac Sci, Beirut - Lebanon
[11] Univ Wollongong, Ctr Med Radiat Phys, Wollongong, NSW 2522 - Australia
[12] Ecoanalytica, Moscow 119899 - Russia
[13] Geant4 Associates Int Ltd, Hebden Bridge, W Yorkshire - England
[14] Univ Notre Dame, Notre Dame Radiat Lab, Notre Dame, IN 46556 - USA
[15] Univ Ioannina, Sch Med, Med Phys Lab, GR-45110 Ioannina - Greece
[16] IRSN, BP17, F-92962 Fontenay Aux Roses - France
[17] Natl Lab High Energy Phys, KEK, Tsukuba, Ibaraki 305 - Japan
[18] Univ Belgrade, Vinca Inst Nucl Sci, Belgrade - Serbia
[19] Ton Duc Thang Univ, Div Nucl Phys, Ho Chi Minh City - Vietnam
[20] Ton Duc Thang Univ, Fac Sci Appl, Ho Chi Minh City - Vietnam
[21] Univ Bordeaux, CENBG, UMR 5797, F-33170 Gradignan - France
[22] CNRS, IN2P3, CENBG, UMR 5797, F-33170 Gradignan - France
Total Affiliations: 22
|
| Document type: | Review article |
| Source: | PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS; v. 31, n. 8, p. 861-874, DEC 2015. |
| Web of Science Citations: | 105 |
| Abstract | |
Understanding the fundamental mechanisms involved in the induction of biological damage by ionizing radiation remains a major challenge of today's radiobiology research. The Monte Carlo simulation of physical, physicochemical and chemical processes involved may provide a powerful tool for the simulation of early damage induction. The Geant4-DNA extension of the general purpose Monte Carlo Geant4 simulation toolkit aims to provide the scientific community with an open source access platform for the mechanistic simulation of such early damage. This paper presents the most recent review of the Geant4-DNA extension, as available to Geant4 users since June 2015 (release 10.2 Beta). In particular, the review includes the description of new physical models for the description of electron elastic and inelastic interactions in liquid water, as well as new examples dedicated to the simulation of physicochemical and chemical stages of water radiolysis. Several implementations of geometrical models of biological targets are presented as well, and the list of Geant4-DNA examples is described. (C) 2015 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved. (AU) | |
| FAPESP's process: | 11/51594-2 - Development of a computational system for the simulation of the interaction of ionizing radiations with the human genetic material |
| Grantee: | Mario Antonio Bernal Rodriguez |
| Support Opportunities: | Research Grants - Young Investigators Grants |