Prediction of Cardiorespiratory Fitness by the Six-Minute Step Test and Its Association with Muscle Strength and Power in Sedentary Obese and Lean Young Women: A Cross-Sectional Study

Author(s):Show less -

Carvalho, Livia Pinheiro ^[1] ; Di Thommazo-Luporini, Luciana ^[1] ; Aubertin-Leheudre, Mylene ^[2] ; Bonjorno Junior, Jose Carlos ^[3] ; de Oliveira, Claudio Ricardo ^[3] ; Luporini, Rafael Luis ^[4] ; Mendes, Renata Goncalves ^[1] ; Lopes Zangrando, Katiany Thais ^[1] ; Trimer, Renata ^[1] ; Arena, Ross ^[5] ; Borghi-Silva, Audrey ^[1]

Affiliation

^[1] Univ Fed Sao Carlos, Physiotherapy Dept, Cardiopulm Physiotherapy Lab, Sao Paulo - Brazil

^[2] Univ Quebec, Kinanthropol Dept, Montreal, PQ H3C 3P8 - Canada

^[3] Univ Fed Sao Carlos, Dept Med, Sao Paulo - Brazil

^[4] Santa Casa Misericordia Sao Carlos, Sao Carlos, SP - Brazil

^[5] Univ Illinois, Coll Appl Hlth Sci, Phys Therapy Dept, Integrat Physiol Lab, Chicago, IL - USA

• Document type: Journal article
• Source: PLoS One; v. 10, n. 12 DEC 30 2015.
• Web of Science Citations: 9

Abstract

Impaired cardiorespiratory fitness (CRF) is a hallmark characteristic in obese and lean sedentary young women. Peak oxygen consumption (VO2peak) prediction from the six-minute step test (6MST) has not been established for sedentary females. It is recognized that lower-limb muscle strength and power play a key role during functional activities. The aim of this study was to investigate cardiorespiratory responses during the 6MST and CPX and to develop a predictive equation to estimate VO2peak in both lean and obese subjects. Additionally we aim to investigate how muscle function impacts functional performance. Lean (LN = 13) and obese (OB = 18) women, aged 20-45, underwent a CPX, two 6MSTs, and isokinetic and isometric knee extensor strength and power evaluations. Regression analysis assessed the ability to predict VO2peak from the 6MST, age and body mass index (BMI). CPX and 6MST main outcomes were compared between LN and OB and correlated with strength and power variables. CRF, functional capacity, and muscle strength and power were lower in the OB compared to LN (<0.05). During the 6MST, LN and OB reached similar to 90% of predicted maximal heart rate and similar to 80% of the VO2peak obtained during CPX. BMI, age and number of step cycles (NSC) explained 83% of the total variance in VO2peak. Moderate to strong correlations between VO2peak at CPX and VO2peak at 6MST (r = 0.86), VO2peak at CPX and NSC (r = 0.80), as well as between VO2peak, NSC and muscle strength and power variables were found (p<0.05). These findings indicate the 6MST, BMI and age accurately predict VO2peak in both lean and obese young sedentary women. Muscle strength and power were related to measures of aerobic and functional performance. (AU)

• FAPESP's process: 13/15681-3 - Relationship between peripheral muscle structure and function, inflammation and autonomic regulation in exercise capacity in obese adults
• Grantee: Lívia Pinheiro Carvalho
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• FAPESP's process: 09/01842-0 - Analysis of central and peripheral muscle metabolism and adjustments on dynamic versus resistance exercise in coronary arterial disease patients: effects of resistance physical training program based on anaerobic threshold by different methodologies
• Grantee: Audrey Borghi Silva
• Support Opportunities: Research Grants - Young Investigators Grants
• FAPESP's process: 15/12751-6 - Effects of a combined intervention of a nutritional supplementation associated with a walking exercise training to improve health in sarcopenic-obese elderly men: its influence on fatness and fitness
• Grantee: Lívia Pinheiro Carvalho
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate (Direct)