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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Modified Beer-Lambert law for blood flow

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Author(s):
Baker, Wesley B. [1] ; Parthasarathy, Ashwin B. [1] ; Busch, David R. [1, 2] ; Mesquita, Rickson C. [3] ; Greenberg, Joel H. [4] ; Yodh, A. G. [1]
Total Authors: 6
Affiliation:
[1] Univ Penn, Dept Phys & Astron, Philadelphia, PA 19104 - USA
[2] Childrens Hosp Philadelphia, Div Neurol, Philadelphia, PA 19104 - USA
[3] Univ Estadual Campinas, Inst Phys, BR-13083859 Campinas, SP - Brazil
[4] Univ Penn, Dept Neurol, Philadelphia, PA 19104 - USA
Total Affiliations: 4
Document type: Journal article
Source: BIOMEDICAL OPTICS EXPRESS; v. 5, n. 11, p. 4053-4075, NOV 1 2014.
Web of Science Citations: 59
Abstract

We develop and validate a Modified Beer-Lambert law for blood flow based on diffuse correlation spectroscopy (DCS) measurements. The new formulation enables blood flow monitoring from temporal intensity autocorrelation function data taken at single or multiple delay-times. Consequentially, the speed of the optical blood flow measurement can be substantially increased. The scheme facilitates blood flow monitoring of highly scattering tissues in geometries wherein light propagation is diffusive or non-diffusive, and it is particularly well-suited for utilization with pressure measurement paradigms that employ differential flow signals to reduce contributions of superficial tissues. (C) 2014 Optical Society of America (AU)

FAPESP's process: 13/07559-3 - BRAINN - The Brazilian Institute of Neuroscience and Neurotechnology
Grantee:Fernando Cendes
Support type: Research Grants - Research, Innovation and Dissemination Centers - RIDC
FAPESP's process: 12/02500-8 - Instrumentation and methodology development for cerebral oxygenation, blood flow and metabolic monitoring with diffuse optical spectroscopies
Grantee:Rickson Coelho Mesquita
Support type: Research Grants - Young Investigators Grants