| Full text | |
| Author(s): |
Yu, Da-Gang
[1]
;
de Azambuja, Francisco
[1]
;
Gensch, Tobias
[1]
;
Daniliuc, Constantin G.
[1]
;
Glorius, Frank
[1]
Total Authors: 5
|
| Affiliation: | [1] Univ Munster, Inst Organ Chem, D-48149 Munster - Germany
Total Affiliations: 1
|
| Document type: | Journal article |
| Source: | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION; v. 53, n. 36, p. 9650-9654, SEP 1 2014. |
| Web of Science Citations: | 82 |
| Abstract | |
The reactivity and selectivity of 1,3-diynes in transition-metal-catalyzed C-H activation is exploited to quickly assemble diverse polysubstituted bisheterocycles, which are highly important but difficult to access. By using the C-H activation/1,3-diyne strategy, we overcame the challenges of selectivity (chemo-, regio-, and mono-/diannulation) and constructed seven kinds of adjacent bisheterocycles through the formation of four strategic bonds with high efficiency and high selectivity. (AU) | |
| FAPESP's process: | 13/14209-9 - Development of a new intermolecular asymmetric Fujiwara-Moritani reaction: a new synthetic tool to obtain biologically active moieties |
| Grantee: | Francisco de Azambuja |
| Support Opportunities: | Scholarships abroad - Research Internship - Doctorate |