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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

RP-HPLC method for estimation of sesamin in two Zanthoxylum species

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Author(s):
Henrique, Camila Y. [1] ; Bertanha, Camila S. [1] ; Alvarenga, Tavane A. [1] ; Silva, Marcio L. A. [1] ; Cunha, Wilson R. [1] ; Januario, Ana H. [1] ; Pauletti, Patricia M. [1]
Total Authors: 7
Affiliation:
[1] Univ Franca, Nucleo Pesquisa Ciencias Exatase & Tecnol, Ave Dr Armando Salles de Oliveira 201, BR-14404600 Franca, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Journal of Liquid Chromatography & Related Technologies; v. 39, n. 2, p. 65-69, JAN 20 2016.
Web of Science Citations: 1
Abstract

Zanthoxylum naranjillo and Z. tingoassuiba (Rutaceae) are traditional herbal medicines with various biological activities including anti-inflammatory, analgesic, and antimalarial action. In this work, we have developed a simple HPLC-DAD method to quantify sesamin, a bioactive lignan present in Z. naranjillo and Z. tingoassuiba; egonol was the internal standard. According to the developed method, 11.07 +/- 1.66, 8.69 +/- 0.95, and 15.11 +/- 0.72 mu g/mL sesamin was present in the ethanol extract of Z. naranjillo leaves, in the methanol extract of Z. naranjillo leaves, and in the methanol extract of Z. tingoassuiba bark, respectively. The limits of detection and quantification were 0.32 and 1.06 mu g/mL, respectively. The developed method can be easily applied during routine analysis of sesamin in these medicinal plants. (AU)

FAPESP's process: 08/01268-9 - Phytochemical study and evaluation of the antimalarial, antimicrobial and acetylcholinesterase inhibition activities from the São Paulo State cerrado native species
Grantee:Ana Helena Januário
Support Opportunities: Regular Research Grants