| Full text | |
| Author(s): |
Paulino, Niraldo
[1, 2]
;
Paulino, Amarilis Scremin
[3]
;
Diniz, Susana N.
[1, 2]
;
de Mendonca, Sergio
[1, 2]
;
Goncalves, Ivair D.
[1, 2]
;
Flores, Fernanda Faiao
[4]
;
Santos, Reginaldo Pereira
[1, 2]
;
Rodrigues, Carina
[1, 2]
;
Pardi, Paulo Celso
[1, 2]
;
Quincoces Suarez, Jose Agustin
[1, 2]
Total Authors: 10
|
| Affiliation: | [1] Univ Anhanguera Sao Paulo UNIAN SP, Programa Posgrad Farm, Programa Mestrado Profiss Farm, Rua Maria Candida, 1813 Vila Guilherme, BR-02071013 Sao Paulo, SP - Brazil
[2] Programa Mestrado & Doutorado Biotecnol & Inovaca, Rua Maria Candida, 1813 Vila Guilherme, BR-02071013 Sao Paulo, SP - Brazil
[3] Univ Fed Santa Catarina, Dept Ciencias Farmaceut, Campus Univ Trindade, BR-88040400 Florianopolis, SC - Brazil
[4] Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Anal Clin & Toxicol, Cidade Univ, BR-05508900 Sao Paulo, SP - Brazil
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | Bioorganic & Medicinal Chemistry; v. 24, n. 8, p. 1927-1935, APR 15 2016. |
| Web of Science Citations: | 7 |
| Abstract | |
This work describes the anti-inflammatory effect of the curcumin-analog compound, sodium 4-{[}5-(4-hydroxy-3-methoxyphenyl)-3-oxo-penta-1,4-dienyl]-2-methoxy-phe nolate (DM1), and shows that DM1 modulates iNOS and COX-2 gene expression in cultured RAW 264.7 cells and induces autophagy on human melanoma cell line A375. (C) 2016 Elsevier Ltd. All rights reserved. (AU) | |
| FAPESP's process: | 11/50435-8 - Synthesis of biologically active phenols and derivatives |
| Grantee: | José Agustín Pablo Quincoces Suárez |
| Support Opportunities: | Regular Research Grants |